Abstract: A stent that can further reduce the incidence of repeated stenosis (restenosis) that has been experienced in conventional stents is provided. Onto the outer surface of a stent body, a structure for cutting body tissues and the like is disposed so that during stent expansion in the outward radial direction and placement, the body tissues, such as blood vessels, are cut. Thus, the stress and unrestricted damage applied to body tissues such as blood vessels can be reduced, and restenosis can be suppressed. By coating the stent with a drug, a stent having enhanced effects can be provided.

Abstract: As a therapy for angiostenosis, angioplasty (PTA, PTCA), in which a small balloon is inflated in a blood vessel to expand the vessel, has been widely practiced as a minimally invasive treatment. In this therapy, however, repeated stenosis (restenosis) occurs at a high incidence. In order to reduce the restenosis rate, procedures that use indwelling stents have gained popularity in recent years. However, restenosis has been reported in about 20% to 30% of stent placement cases. Although attempts have been made to coat the stent with a drug that regulates occlusion, stenosis still occurs at a high frequency. At least two layers including an immunosuppressant-containing layer and an antiinflammatory agent-containing layer are provided on the surface of an indwelling stent.