Abstract: A reactor provided with a fluidized chamber is characterized in that the fluidized chamber is connected with a column chamber, an inner tube movable in the fluidized chamber is provided, the inner tube is arranged to be brought into contact with the column chamber through the fluidized chamber and nets for preventing outflow of immobilized biocatalyst, gel, immobilized carrier or the like are provided at the head opening of the inner tube and the column chamber, respectively.

Abstract: The present invention relates to a method of disinfecting immobilized biocatalysts in which the extinguishing of microbes adhering to carriers without lowering the activity of immobilized biocatalysts by irradiating ultraviolet light to immobilized biocatalysts at the illuminating power of less than 0.5mW/cm.sup.2, and to a reactor provided with fluidized chamber wherein a column chamber with outflow-preventing net is connected with an end of fluidized chamber, and an inner tube with an outflow-preventing net at the head opening and at the same time movable in the fluidized chamber is connected with a column chamber, and at the other side of the fluidized chamber a washing gateway with an outflow-preventing net is connected so as to be able to be washing, disinfecting, adsorbing and eluting of reaction continuously.