Patents by Inventor Ryoichi Kawamura
Ryoichi Kawamura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240133792Abstract: The present disclosure provides methods and systems for ghost cytometry (GC), which may be used to produce an image of an object without using a spatially resolving detector. This may be used to perform image-free ultrafast fluorescence “imaging” cytometry, based on, for example, a single pixel detector. Spatial information obtained from the motion of cells relative to a patterned optical structure may be compressively converted into signals that arrive sequentially at a single pixel detector. Combinatorial use of the temporal waveform with the intensity distribution of the random or pseudo-random pattern may permit computational reconstruction of cell morphology. Machine learning methods may be applied directly to the compressed waveforms without image reconstruction to enable efficient image-free morphology-based cytometry.Type: ApplicationFiled: August 25, 2023Publication date: April 25, 2024Inventors: Sadao Ota, Ryoichi Horisaki, Yoko Kawamura, Masashi Ugawa, Issei Sato
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Patent number: 11433160Abstract: A formed sheet product of a polymer composition comprising at least one protein selected from the group consisting of fibrinogen and thrombin and at least one polymer selected from the group consisting of an aliphatic polyester and a water-soluble polymer, and a laminated formed sheet product comprising a first polymer composition layer composed of fibrinogen and a water-soluble polymer and a second polymer composition layer composed of thrombin and an aliphatic polyester are provided. These formed products are applied onto a wound site and function as a hemostatic material.Type: GrantFiled: October 22, 2019Date of Patent: September 6, 2022Assignees: TEIJIN LIMITED, KM BIOLOGICS CO., LTD.Inventors: Yukako Kageyama, Kentaro Fujinaga, Ayuko Yamaguchi, Yusuke Akiyama, Akitoshi Oono, Susumu Honda, Makoto Satake, Hiroaki Kaneko, Takayuki Imamura, Ryoichi Kawamura, Masaki Hirashima
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Publication number: 20200046877Abstract: A formed sheet product of a polymer composition comprising at least one protein selected from the group consisting of fibrinogen and thrombin and at least one polymer selected from the group consisting of an aliphatic polyester and a water-soluble polymer, and a laminated formed sheet product comprising a first polymer composition layer composed of fibrinogen and a water-soluble polymer and a second polymer composition layer composed of thrombin and an aliphatic polyester are provided. These formed products are applied onto a wound site and function as a hemostatic material.Type: ApplicationFiled: October 22, 2019Publication date: February 13, 2020Applicants: TEIJIN LIMITED, Teijin Pharma Limited, KM BIOLOGICS CO., LTD.Inventors: Yukako KAGEYAMA, Kentaro Fujinaga, Ayuko Yamaguchi, Yusuke Aklyama, Akitoshi Oono, Susumu Honda, Makoto Satake, Hiroaki Kaneko, Takayuki Imamura, Ryoichi Kawamura, Masaki Hirashima
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Patent number: 10485894Abstract: A formed sheet product of a polymer composition comprising at least one protein selected from the group consisting of fibrinogen and thrombin and at least one polymer selected from the group consisting of an aliphatic polyester and a water-soluble polymer, and a laminated formed sheet product comprising a first polymer composition layer composed of fibrinogen and a water-soluble polymer and a second polymer composition layer composed of thrombin and an aliphatic polyester are provided. These formed products are applied onto a wound site and function as a hemostatic material.Type: GrantFiled: May 13, 2013Date of Patent: November 26, 2019Assignees: TEIJIN LIMITED, Teijin Pharma Limited, KM BIOLOGICS CO., LTD.Inventors: Yukako Kageyama, Kentaro Fujinaga, Ayuko Yamaguchi, Yusuke Akiyama, Akitoshi Oono, Susumu Honda, Makoto Satake, Hiroaki Kaneko, Takayuki Imamura, Ryoichi Kawamura, Masaki Hirashima
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Patent number: 9175295Abstract: A modified transposon vector and a method for introducing a foreign gene into a cell are provided.Type: GrantFiled: July 4, 2006Date of Patent: November 3, 2015Assignee: THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTEInventors: Kazuyoshi Kaminaka, Hiroaki Maeda, Masaki Hirashima, Ryoichi Kawamura, Junichi Matsuda, Takashi Kuwana
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Patent number: 9149557Abstract: A process for preparing a bioabsorbable sheet preparation holding thrombin is provided. A process for preparing a bioabsorbable sheet preparation holding thrombin which comprises immersing a bioabsorbable sheet consisting of polyglycolic acid in a thrombin solution containing thrombin as an active ingredient, glycerol as a softening agent, Tween 80 as a permeating agent, and optionally histidine and trehalose as a stabilizing agent followed by drying to hold thrombin on said bioabsorbable sheet, and a bioabsorbable sheet preparation holding thrombin prepared by said process.Type: GrantFiled: April 15, 2009Date of Patent: October 6, 2015Assignee: THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTEInventors: Ryoichi Kawamura, Takayuki Imamura, Hitomi Owaki
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Patent number: 9091587Abstract: A label printing scale device includes separable casings that are vertically overlaid in two levels, one on top of the other. Specifically, the label printing scale device includes an upper casing housing at least a load cell and a circuit part, and a lower casing housing at least power-generation circuit, a printer, and a control part.Type: GrantFiled: February 23, 2012Date of Patent: July 28, 2015Assignee: ISHIDA CO., LTD.Inventors: Ryoichi Kawamura, Kengo Aoyama
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Publication number: 20150151020Abstract: A formed sheet product of a polymer composition comprising at least one protein selected from the group consisting of fibrinogen and thrombin and at least one polymer selected from the group consisting of an aliphatic polyester and a water-soluble polymer, and a laminated formed sheet product comprising a first polymer composition layer composed of fibrinogen and a water-soluble polymer and a second polymer composition layer composed of thrombin and an aliphatic polyester are provided. These formed products are applied onto a wound site and function as a hemostatic material.Type: ApplicationFiled: May 13, 2013Publication date: June 4, 2015Applicants: TEIJIN LIMITED, TEIJIN PHARMA LIMITED, THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTEInventors: Yukako Kageyama, Kentaro Fujinaga, Ayuko Yamaguchi, Yusuke Akiyama, Akitoshi Oono, Susumu Honda, Makoto Satake, Hiroaki Kaneko, Takayuki Imamura, Ryoichi Kawamura, Masaki Hirashima
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Patent number: 8679783Abstract: A Factor X (hereinafter referred to as “FX”) with a high activity is provided. The present invention relates to a method for efficiently preparing a recombinant, two-chain FX which comprises intervening glycosylation at such an amino acid sequence that is essential for glycosylation in FX to thereby allow for expression of a recombinant FX with no glycosylation, and the recombinant FX with no glycosylation obtained by said method.Type: GrantFiled: February 24, 2012Date of Patent: March 25, 2014Assignee: The Chemo-Sero-Therapeutic Research InstituteInventors: Kenji Soejima, Takayuki Imamura, Ryoichi Kawamura, Hiroshi Nakatake, Arisa Maeyashiki, Hitomi Togo
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Patent number: 8293874Abstract: A Factor X (hereinafter referred to as “FX”) with a high activity is provided. The present invention relates to a method for efficiently preparing a recombinant, two-chain FX which comprises intervening glycosylation at such an amino acid sequence that is essential for glycosylation in FX to thereby allow for expression of a recombinant FX with no glycosylation, and the recombinant FX with no glycosylation obtained by said method.Type: GrantFiled: September 16, 2011Date of Patent: October 23, 2012Assignee: Juridical Foundation The Chemo-Sero-Therapeutic Research InstituteInventors: Kenji Soejima, Takayuki Imamura, Ryoichi Kawamura, Hiroshi Nakatake, Arisa Maeyashiki, Hitomi Togo
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Publication number: 20120231523Abstract: A Factor X (hereinafter referred to as “FX”) with a high activity is provided. The present invention relates to a method for efficiently preparing a recombinant, two-chain FX which comprises intervening glycosylation at such an amino acid sequence that is essential for glycosylation in FX to thereby allow for expression of a recombinant FX with no glycosylation, and the recombinant FX with no glycosylation obtained by said method.Type: ApplicationFiled: February 24, 2012Publication date: September 13, 2012Applicant: JURIDICAL FDN THE CHEMO-SERO-THERAPEUTIC RES INSTInventors: Kenji Soejima, Takayuki Imamura, Ryoichi Kawamura, Hiroshi Nakatake, Arisa Maeyashiki, Hitomi Togo
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Publication number: 20120217069Abstract: A label printing scale device includes separable casings that are vertically overlaid in two levels, one on top of the other. Specifically, the label printing scale device includes an upper casing housing at least a load cell and a circuit part, and a lower casing housing at least power-generation circuit, a printer, and a control part.Type: ApplicationFiled: February 23, 2012Publication date: August 30, 2012Applicant: ISHIDA CO., LTD.Inventors: Ryoichi KAWAMURA, Kengo AOYAMA
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Patent number: 8173777Abstract: A Factor X (hereinafter referred to as “FX”) with a high activity is provided. The present invention relates to a method for efficiently preparing a recombinant, two-chain FX which comprises intervening glycosylation at such an amino acid sequence that is essential for glycosylation in FX to thereby allow for expression of a recombinant FX with no glycosylation, and the recombinant FX with no glycosylation obtained by said method.Type: GrantFiled: October 8, 2008Date of Patent: May 8, 2012Assignee: Juridical Foundation the Chemo-Sero-Therapeutic Research InstituteInventors: Kenji Soejima, Takayuki Imamura, Ryoichi Kawamura, Hiroshi Nakatake, Arisa Maeyashiki, Hitomi Togo
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Publication number: 20120039863Abstract: A Factor X (hereinafter referred to as “FX”) with a high activity is provided. The present invention relates to a method for efficiently preparing a recombinant, two-chain FX which comprises intervening glycosylation at such an amino acid sequence that is essential for glycosylation in FX to thereby allow for expression of a recombinant FX with no glycosylation, and the recombinant FX with no glycosylation obtained by said method.Type: ApplicationFiled: September 16, 2011Publication date: February 16, 2012Applicant: JURIDICAL FDN THE CHEMO-SERO-THERAPEUTIC RES INSTInventors: Kenji SOEJIMA, Takayuki Imamura, Ryoichi Kawamura, Hiroshi Nakatake, Arisa Maeyashiki, Hitomi Togo
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Publication number: 20110183911Abstract: A novel medicament for ameliorating neurotransmission dysfunction diseases is provided. A medicament for ameliorating neurotransmission dysfunction diseases comprising as a main active ingredient preferably a selenocysteine-containing protein such as Selenoprotein P or a selenocysteine-containing peptide that consists of said protein or a series of said peptides. A medicament suited for ameliorating neurotransmission dysfunction diseases caused by various pathological conditions is provided.Type: ApplicationFiled: January 24, 2011Publication date: July 28, 2011Applicant: JURIDICAL FOUNDATION THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTTITUTEInventors: Ryoichi Kawamura, Takeshi Naruse, Masaki Hirashima, Kazuyoshi Kaminaka, Junichi Matsuda, Hiroaki Maeda, Mami Noda, Keiji Wada
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Publication number: 20110038847Abstract: A process for preparing a bioabsorbable sheet preparation holding thrombin is provided. A process for preparing a bioabsorbable sheet preparation holding thrombin which comprises immersing a bioabsorbable sheet consisting of polyglycolic acid in a thrombin solution containing thrombin as an active ingredient, glycerol as a softening agent, Tween 80 as a permeating agent, and optionally histidine and trehalose as a stabilizing agent followed by drying to hold thrombin on said bioabsorbable sheet, and a bioabsorbable sheet preparation holding thrombin prepared by said process.Type: ApplicationFiled: April 15, 2009Publication date: February 17, 2011Applicant: THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTEInventors: Ryoichi Kawamura, Takayuki Imamura, Hitomi Owaki
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Publication number: 20110023413Abstract: A packaging apparatus includes a conveying unit that conveys a continuous film in a first direction with an article placed on a first portion of the film, and folds back in a second direction opposite to the first direction a second portion of the film ahead of the first portion with respect to the first direction, sealing parts that seal the first portion and the second portion to form a bag body containing the article, and a cutter that cuts the film.Type: ApplicationFiled: July 26, 2010Publication date: February 3, 2011Applicant: ISHIDA CO., LTD.Inventors: Akihito SUZUKI, Ryoichi KAWAMURA, Yuuki TAI, Koji ARAKI, Tsuyoshi ONO, Tetsuya TSUDA
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Publication number: 20100285568Abstract: A Factor X (hereinafter referred to as “FX”) with a high activity is provided. The present invention relates to a method for efficiently preparing a recombinant, two-chain FX which comprises intervening glycosylation at such an amino acid sequence that is essential for glycosylation in FX to thereby allow for expression of a recombinant FX with no glycosylation, and the recombinant FX with no glycosylation obtained by said method.Type: ApplicationFiled: October 8, 2008Publication date: November 11, 2010Applicant: JURIDICAL FDN THE CHEMO-SERO-THERAPEUTIC RES INSTInventors: Kenji Soejima, Takayuki Imamura, Ryoichi Kawamura, Hiroshi Nakatake, Arisa Maeyashiki, Hitomi Togo
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Publication number: 20100281551Abstract: A modified transposon vector and a method for introducing a foreign gene into a cell are provided.Type: ApplicationFiled: July 4, 2006Publication date: November 4, 2010Inventors: Kazuyoshi Kaminaka, Hiroaki Maeda, Masaki Hirashima, Ryoichi Kawamura, Junichi Matsuda, Takashi Kuwana
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Publication number: 20070293431Abstract: A novel medicament for ameliorating neurotransmission dysfunction diseases is provided. A medicament for ameliorating neurotransmission dysfunction diseases comprising as a main active ingredient preferably a selenocysteine-containing protein such as Selenoprotein P or a selenocysteine-containing peptide that consists of said protein or a series of said peptides. A medicament suited for ameliorating neurotransmission dysfunction diseases caused by various pathological conditions is provided.Type: ApplicationFiled: July 24, 2007Publication date: December 20, 2007Applicant: Juridical Foundation the Chemo-Sero-Therapeutic Research InstituteInventors: Ryoichi Kawamura, Takeshi Naruse, Masaki Hirashima, Kazuyoshi Kaminaka, Junichi Matsuda, Hiroaki Maeda, Mami Noda, Keiji Wada