Patents by Inventor Ryoichi Kawamura

Ryoichi Kawamura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240133792
    Abstract: The present disclosure provides methods and systems for ghost cytometry (GC), which may be used to produce an image of an object without using a spatially resolving detector. This may be used to perform image-free ultrafast fluorescence “imaging” cytometry, based on, for example, a single pixel detector. Spatial information obtained from the motion of cells relative to a patterned optical structure may be compressively converted into signals that arrive sequentially at a single pixel detector. Combinatorial use of the temporal waveform with the intensity distribution of the random or pseudo-random pattern may permit computational reconstruction of cell morphology. Machine learning methods may be applied directly to the compressed waveforms without image reconstruction to enable efficient image-free morphology-based cytometry.
    Type: Application
    Filed: August 25, 2023
    Publication date: April 25, 2024
    Inventors: Sadao Ota, Ryoichi Horisaki, Yoko Kawamura, Masashi Ugawa, Issei Sato
  • Patent number: 11433160
    Abstract: A formed sheet product of a polymer composition comprising at least one protein selected from the group consisting of fibrinogen and thrombin and at least one polymer selected from the group consisting of an aliphatic polyester and a water-soluble polymer, and a laminated formed sheet product comprising a first polymer composition layer composed of fibrinogen and a water-soluble polymer and a second polymer composition layer composed of thrombin and an aliphatic polyester are provided. These formed products are applied onto a wound site and function as a hemostatic material.
    Type: Grant
    Filed: October 22, 2019
    Date of Patent: September 6, 2022
    Assignees: TEIJIN LIMITED, KM BIOLOGICS CO., LTD.
    Inventors: Yukako Kageyama, Kentaro Fujinaga, Ayuko Yamaguchi, Yusuke Akiyama, Akitoshi Oono, Susumu Honda, Makoto Satake, Hiroaki Kaneko, Takayuki Imamura, Ryoichi Kawamura, Masaki Hirashima
  • Publication number: 20200046877
    Abstract: A formed sheet product of a polymer composition comprising at least one protein selected from the group consisting of fibrinogen and thrombin and at least one polymer selected from the group consisting of an aliphatic polyester and a water-soluble polymer, and a laminated formed sheet product comprising a first polymer composition layer composed of fibrinogen and a water-soluble polymer and a second polymer composition layer composed of thrombin and an aliphatic polyester are provided. These formed products are applied onto a wound site and function as a hemostatic material.
    Type: Application
    Filed: October 22, 2019
    Publication date: February 13, 2020
    Applicants: TEIJIN LIMITED, Teijin Pharma Limited, KM BIOLOGICS CO., LTD.
    Inventors: Yukako KAGEYAMA, Kentaro Fujinaga, Ayuko Yamaguchi, Yusuke Aklyama, Akitoshi Oono, Susumu Honda, Makoto Satake, Hiroaki Kaneko, Takayuki Imamura, Ryoichi Kawamura, Masaki Hirashima
  • Patent number: 10485894
    Abstract: A formed sheet product of a polymer composition comprising at least one protein selected from the group consisting of fibrinogen and thrombin and at least one polymer selected from the group consisting of an aliphatic polyester and a water-soluble polymer, and a laminated formed sheet product comprising a first polymer composition layer composed of fibrinogen and a water-soluble polymer and a second polymer composition layer composed of thrombin and an aliphatic polyester are provided. These formed products are applied onto a wound site and function as a hemostatic material.
    Type: Grant
    Filed: May 13, 2013
    Date of Patent: November 26, 2019
    Assignees: TEIJIN LIMITED, Teijin Pharma Limited, KM BIOLOGICS CO., LTD.
    Inventors: Yukako Kageyama, Kentaro Fujinaga, Ayuko Yamaguchi, Yusuke Akiyama, Akitoshi Oono, Susumu Honda, Makoto Satake, Hiroaki Kaneko, Takayuki Imamura, Ryoichi Kawamura, Masaki Hirashima
  • Patent number: 9175295
    Abstract: A modified transposon vector and a method for introducing a foreign gene into a cell are provided.
    Type: Grant
    Filed: July 4, 2006
    Date of Patent: November 3, 2015
    Assignee: THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE
    Inventors: Kazuyoshi Kaminaka, Hiroaki Maeda, Masaki Hirashima, Ryoichi Kawamura, Junichi Matsuda, Takashi Kuwana
  • Patent number: 9149557
    Abstract: A process for preparing a bioabsorbable sheet preparation holding thrombin is provided. A process for preparing a bioabsorbable sheet preparation holding thrombin which comprises immersing a bioabsorbable sheet consisting of polyglycolic acid in a thrombin solution containing thrombin as an active ingredient, glycerol as a softening agent, Tween 80 as a permeating agent, and optionally histidine and trehalose as a stabilizing agent followed by drying to hold thrombin on said bioabsorbable sheet, and a bioabsorbable sheet preparation holding thrombin prepared by said process.
    Type: Grant
    Filed: April 15, 2009
    Date of Patent: October 6, 2015
    Assignee: THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE
    Inventors: Ryoichi Kawamura, Takayuki Imamura, Hitomi Owaki
  • Patent number: 9091587
    Abstract: A label printing scale device includes separable casings that are vertically overlaid in two levels, one on top of the other. Specifically, the label printing scale device includes an upper casing housing at least a load cell and a circuit part, and a lower casing housing at least power-generation circuit, a printer, and a control part.
    Type: Grant
    Filed: February 23, 2012
    Date of Patent: July 28, 2015
    Assignee: ISHIDA CO., LTD.
    Inventors: Ryoichi Kawamura, Kengo Aoyama
  • Publication number: 20150151020
    Abstract: A formed sheet product of a polymer composition comprising at least one protein selected from the group consisting of fibrinogen and thrombin and at least one polymer selected from the group consisting of an aliphatic polyester and a water-soluble polymer, and a laminated formed sheet product comprising a first polymer composition layer composed of fibrinogen and a water-soluble polymer and a second polymer composition layer composed of thrombin and an aliphatic polyester are provided. These formed products are applied onto a wound site and function as a hemostatic material.
    Type: Application
    Filed: May 13, 2013
    Publication date: June 4, 2015
    Applicants: TEIJIN LIMITED, TEIJIN PHARMA LIMITED, THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE
    Inventors: Yukako Kageyama, Kentaro Fujinaga, Ayuko Yamaguchi, Yusuke Akiyama, Akitoshi Oono, Susumu Honda, Makoto Satake, Hiroaki Kaneko, Takayuki Imamura, Ryoichi Kawamura, Masaki Hirashima
  • Patent number: 8679783
    Abstract: A Factor X (hereinafter referred to as “FX”) with a high activity is provided. The present invention relates to a method for efficiently preparing a recombinant, two-chain FX which comprises intervening glycosylation at such an amino acid sequence that is essential for glycosylation in FX to thereby allow for expression of a recombinant FX with no glycosylation, and the recombinant FX with no glycosylation obtained by said method.
    Type: Grant
    Filed: February 24, 2012
    Date of Patent: March 25, 2014
    Assignee: The Chemo-Sero-Therapeutic Research Institute
    Inventors: Kenji Soejima, Takayuki Imamura, Ryoichi Kawamura, Hiroshi Nakatake, Arisa Maeyashiki, Hitomi Togo
  • Patent number: 8293874
    Abstract: A Factor X (hereinafter referred to as “FX”) with a high activity is provided. The present invention relates to a method for efficiently preparing a recombinant, two-chain FX which comprises intervening glycosylation at such an amino acid sequence that is essential for glycosylation in FX to thereby allow for expression of a recombinant FX with no glycosylation, and the recombinant FX with no glycosylation obtained by said method.
    Type: Grant
    Filed: September 16, 2011
    Date of Patent: October 23, 2012
    Assignee: Juridical Foundation The Chemo-Sero-Therapeutic Research Institute
    Inventors: Kenji Soejima, Takayuki Imamura, Ryoichi Kawamura, Hiroshi Nakatake, Arisa Maeyashiki, Hitomi Togo
  • Publication number: 20120231523
    Abstract: A Factor X (hereinafter referred to as “FX”) with a high activity is provided. The present invention relates to a method for efficiently preparing a recombinant, two-chain FX which comprises intervening glycosylation at such an amino acid sequence that is essential for glycosylation in FX to thereby allow for expression of a recombinant FX with no glycosylation, and the recombinant FX with no glycosylation obtained by said method.
    Type: Application
    Filed: February 24, 2012
    Publication date: September 13, 2012
    Applicant: JURIDICAL FDN THE CHEMO-SERO-THERAPEUTIC RES INST
    Inventors: Kenji Soejima, Takayuki Imamura, Ryoichi Kawamura, Hiroshi Nakatake, Arisa Maeyashiki, Hitomi Togo
  • Publication number: 20120217069
    Abstract: A label printing scale device includes separable casings that are vertically overlaid in two levels, one on top of the other. Specifically, the label printing scale device includes an upper casing housing at least a load cell and a circuit part, and a lower casing housing at least power-generation circuit, a printer, and a control part.
    Type: Application
    Filed: February 23, 2012
    Publication date: August 30, 2012
    Applicant: ISHIDA CO., LTD.
    Inventors: Ryoichi KAWAMURA, Kengo AOYAMA
  • Patent number: 8173777
    Abstract: A Factor X (hereinafter referred to as “FX”) with a high activity is provided. The present invention relates to a method for efficiently preparing a recombinant, two-chain FX which comprises intervening glycosylation at such an amino acid sequence that is essential for glycosylation in FX to thereby allow for expression of a recombinant FX with no glycosylation, and the recombinant FX with no glycosylation obtained by said method.
    Type: Grant
    Filed: October 8, 2008
    Date of Patent: May 8, 2012
    Assignee: Juridical Foundation the Chemo-Sero-Therapeutic Research Institute
    Inventors: Kenji Soejima, Takayuki Imamura, Ryoichi Kawamura, Hiroshi Nakatake, Arisa Maeyashiki, Hitomi Togo
  • Publication number: 20120039863
    Abstract: A Factor X (hereinafter referred to as “FX”) with a high activity is provided. The present invention relates to a method for efficiently preparing a recombinant, two-chain FX which comprises intervening glycosylation at such an amino acid sequence that is essential for glycosylation in FX to thereby allow for expression of a recombinant FX with no glycosylation, and the recombinant FX with no glycosylation obtained by said method.
    Type: Application
    Filed: September 16, 2011
    Publication date: February 16, 2012
    Applicant: JURIDICAL FDN THE CHEMO-SERO-THERAPEUTIC RES INST
    Inventors: Kenji SOEJIMA, Takayuki Imamura, Ryoichi Kawamura, Hiroshi Nakatake, Arisa Maeyashiki, Hitomi Togo
  • Publication number: 20110183911
    Abstract: A novel medicament for ameliorating neurotransmission dysfunction diseases is provided. A medicament for ameliorating neurotransmission dysfunction diseases comprising as a main active ingredient preferably a selenocysteine-containing protein such as Selenoprotein P or a selenocysteine-containing peptide that consists of said protein or a series of said peptides. A medicament suited for ameliorating neurotransmission dysfunction diseases caused by various pathological conditions is provided.
    Type: Application
    Filed: January 24, 2011
    Publication date: July 28, 2011
    Applicant: JURIDICAL FOUNDATION THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTTITUTE
    Inventors: Ryoichi Kawamura, Takeshi Naruse, Masaki Hirashima, Kazuyoshi Kaminaka, Junichi Matsuda, Hiroaki Maeda, Mami Noda, Keiji Wada
  • Publication number: 20110038847
    Abstract: A process for preparing a bioabsorbable sheet preparation holding thrombin is provided. A process for preparing a bioabsorbable sheet preparation holding thrombin which comprises immersing a bioabsorbable sheet consisting of polyglycolic acid in a thrombin solution containing thrombin as an active ingredient, glycerol as a softening agent, Tween 80 as a permeating agent, and optionally histidine and trehalose as a stabilizing agent followed by drying to hold thrombin on said bioabsorbable sheet, and a bioabsorbable sheet preparation holding thrombin prepared by said process.
    Type: Application
    Filed: April 15, 2009
    Publication date: February 17, 2011
    Applicant: THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE
    Inventors: Ryoichi Kawamura, Takayuki Imamura, Hitomi Owaki
  • Publication number: 20110023413
    Abstract: A packaging apparatus includes a conveying unit that conveys a continuous film in a first direction with an article placed on a first portion of the film, and folds back in a second direction opposite to the first direction a second portion of the film ahead of the first portion with respect to the first direction, sealing parts that seal the first portion and the second portion to form a bag body containing the article, and a cutter that cuts the film.
    Type: Application
    Filed: July 26, 2010
    Publication date: February 3, 2011
    Applicant: ISHIDA CO., LTD.
    Inventors: Akihito SUZUKI, Ryoichi KAWAMURA, Yuuki TAI, Koji ARAKI, Tsuyoshi ONO, Tetsuya TSUDA
  • Publication number: 20100285568
    Abstract: A Factor X (hereinafter referred to as “FX”) with a high activity is provided. The present invention relates to a method for efficiently preparing a recombinant, two-chain FX which comprises intervening glycosylation at such an amino acid sequence that is essential for glycosylation in FX to thereby allow for expression of a recombinant FX with no glycosylation, and the recombinant FX with no glycosylation obtained by said method.
    Type: Application
    Filed: October 8, 2008
    Publication date: November 11, 2010
    Applicant: JURIDICAL FDN THE CHEMO-SERO-THERAPEUTIC RES INST
    Inventors: Kenji Soejima, Takayuki Imamura, Ryoichi Kawamura, Hiroshi Nakatake, Arisa Maeyashiki, Hitomi Togo
  • Publication number: 20100281551
    Abstract: A modified transposon vector and a method for introducing a foreign gene into a cell are provided.
    Type: Application
    Filed: July 4, 2006
    Publication date: November 4, 2010
    Inventors: Kazuyoshi Kaminaka, Hiroaki Maeda, Masaki Hirashima, Ryoichi Kawamura, Junichi Matsuda, Takashi Kuwana
  • Publication number: 20070293431
    Abstract: A novel medicament for ameliorating neurotransmission dysfunction diseases is provided. A medicament for ameliorating neurotransmission dysfunction diseases comprising as a main active ingredient preferably a selenocysteine-containing protein such as Selenoprotein P or a selenocysteine-containing peptide that consists of said protein or a series of said peptides. A medicament suited for ameliorating neurotransmission dysfunction diseases caused by various pathological conditions is provided.
    Type: Application
    Filed: July 24, 2007
    Publication date: December 20, 2007
    Applicant: Juridical Foundation the Chemo-Sero-Therapeutic Research Institute
    Inventors: Ryoichi Kawamura, Takeshi Naruse, Masaki Hirashima, Kazuyoshi Kaminaka, Junichi Matsuda, Hiroaki Maeda, Mami Noda, Keiji Wada