Abstract: A method for manufacturing a can by deep drawing using a press machine, the can being a quadrilateral can having a rectangular opening, the method including controlling a temperature of a punch and/or a temperature of a die by supplying a heat medium as a fluid to a flow path provided inside the punch and/or the die.

Abstract: A drug or agent containing a compound having an agonistic activity to STING as an active ingredient, where the compound is represented by the following general formula (I-1): wherein all symbols represent the same meanings as described in the specification, and the compound can be used as an active ingredient of an agent for suppressing the progression of, suppressing the recurrence of and/or treating cancer or infectious disease.

Abstract: A square can manufacturing method and a square can manufacturing apparatus that suppress the occurrence of nonuniformity in thickness of a long side wall without increasing the manufacturing cost are provided. The square can manufacturing method includes drawing and ironing at a planned cylindrical part of an intermediate molded product. In the square can manufacturing method, a die and a punch are formed such that in a state where the punch is inserted into a die machining through hole in an unloaded state, a distance in a short side direction between a center portion of a punch long side wall machining part in a long side direction and a die long side wall machining part is smaller than a distance in the short side direction between both end portions of the punch long side wall machining part in the long side direction and the die long side wall machining part.

Abstract: Provided are a square can manufacturing method and a square can manufacturing apparatus. The square can manufacturing method includes a shape correction step of correcting the shape of an intermediate molded product, and in the shape correction step, a distance in a short side direction between planned long side wall parts of the intermediate molded product is expanded by pushing the planned long side wall parts outward in the short side direction by a long side wall pressing part of a shape correction punch inserted in the intermediate molded product, and a planned bottom wall part of the intermediate molded product is planarized by sandwiching the planned bottom wall part between a bottom wall pressing part of the shape correction punch inserted in the intermediate molded product and a bottom wall pressing member disposed on an outer surface side of the planned bottom wall part.

Abstract: A drug or agent containing a compound having an agonistic activity to STING as an active ingredient, where the compound is represented by the following general formula (I-1): wherein all symbols represent the same meanings as described in the specification, and the compound can be used as an active ingredient of an agent for suppressing the progression of, suppressing the recurrence of and/or treating cancer or infectious disease.

Abstract: A drug or agent containing a compound having an agonistic activity to STING as an active ingredient, where the compound is represented by the following general formula (I-1): wherein all symbols represent the same meanings as described in the specification, and the compound can be used as an active ingredient of an agent for suppressing the progression of, suppressing the recurrence of and/or treating cancer or infectious disease.

Abstract: A drug or agent containing a compound having an agonistic activity to STING as an active ingredient, where the compound is represented by the following general formula (I-1): wherein all symbols represent the same meanings as described in the specification, and the compound can be used as an active ingredient of an agent for suppressing the progression of, suppressing the recurrence of and/or treating cancer or infectious disease.

Abstract: The object of the present invention is to provide a drug containing a compound having an agonistic activity to STING as an active ingredient. As a result of intensive studies by the inventors of the present invention, the compound represented by the following general formula (I-1) [in the formula, all symbols represent the same meanings as described in the present specification.] or the like, having the agonistic activity to STING, as a substance capable of solving such objects, and this invention was completed. Since the compound represented by the general formula (I-1) or the like of the present invention has the agonistic activity to STING, it can be used as an active ingredient of an agent for suppressing the progression of, suppressing the recurrence of and/or treating cancer or infectious disease.

Abstract: A drug or agent containing a compound having an agonistic activity to STING as an active ingredient, where the compound is represented by the following general formula (I-1): wherein all symbols represent the same meanings as described in the specification, and the compound can be used as an active ingredient of an agent for suppressing the progression of, suppressing the recurrence of and/or treating cancer or infectious disease.

Abstract: A drug or agent containing a compound having an agonistic activity to STING as an active ingredient, where the compound is represented by the following general formula (I-1): wherein all symbols represent the same meanings as described in the specification, and the compound can be used as an active ingredient of an agent for suppressing the progression of, suppressing the recurrence of and/or treating cancer or infectious disease.

Abstract: A drug or agent containing a compound having an agonistic activity to STING as an active ingredient, where the compound is represented by the following general formula (I-1): wherein all symbols represent the same meanings as described in the specification, and the compound can be used as an active ingredient of an agent for suppressing the progression of, suppressing the recurrence of and/or treating cancer or infectious disease.