Abstract: The invention relates to an antibody which binds to chondroitin sulfate proteoglycan 5 (CSPG5) or an antibody fragment thereof, a hybridoma which produces the antibody or the antibody fragment thereof, a nucleic acid comprising a nucleotide sequence encoding the antibody or the antibody fragment thereof, a transformant cell comprising a vector comprising the nucleic acid, a method for producing the antibody or the antibody fragment thereof, a composition comprising the antibody or the antibody fragment thereof, and a method for detecting or measuring an antigen present in the brain, a method for diagnosing or treating a brain disease, a method for enhancing the property of accumulating in a brain of an antibody, and a method for increasing the amount of an antibody in the brain, each of which using the antibody or the antibody fragment thereof, and the like.

Abstract: The invention relates to an antibody which binds to myelin oligodendrocyte glycoprotein (MOG), an antibody fragment thereof, a hybridoma which produces the antibody or the antibody fragment, a nucleic acid containing a nucleotide sequence which encodes the antibody or the antibody fragment, a transformant cell containing a vector containing the nucleic acid, a method for producing the antibody or the antibody fragment, a composition containing the antibody or the antibody fragment and a method for detecting or measuring an antigen that is present in the brain, a method for diagnosing or treating a brain disease, a method for improving the property of an antibody of accumulating in the brain and a method for increasing the amount of an antibody in the brain which use the antibody or the antibody fragment.

Abstract: A power loss of a switching device is suppressed. Circuit for a switching device is used in switching device. Switching device includes first path and second path. First path includes first field effect transistor and first inductor. Second path includes second field effect transistor and second inductor. First path and second path are connected in parallel to power supply. A first maximum current that is a maximum current during conduction of first field effect transistor is smaller than a second maximum current that is a maximum current during conduction of second field effect transistor. Circuit for a switching device includes processing part. Processing part executes a specific operation according to a voltage difference between voltage across first inductor and voltage across second inductor.

Abstract: A control circuit controls a switching element including a gate and a source corresponding to the gate. The control circuit includes an inductor, a circuit element, and a resistor. The inductor is connected between the gate and the source of the switching element. The circuit element is connected in series to the inductor between the gate and the source. The circuit element allows an electric current to flow therethrough in response to generation of electromotive force in the inductor. The resistor is connected in parallel to the inductor and the circuit element between the gate and the source.

Abstract: In cooling/heating cycles of a heat exchanger, to prevent cracks that tend to occur in a brazed portion between an end portion of a horizontal cross-section of a tube and a header plate. An end portion cover body is provided for an end portion of a tank main body or a header to cover hereby an end portion in a longer side direction of an opening end portion of a flat tube.

Abstract: A work vehicle includes: a hydraulic pump driven by an engine; a hydraulic actuator that is driven by hydraulic oil supplied from the hydraulic pump; a switching valve configured to switch from one to the other of a first state in which the hydraulic oil supplied from the hydraulic pump is supplied to a first channel and a second state in which the hydraulic oil supplied from the hydraulic pump is supplied to a second channel; a restriction operation device configured to generate an operation signal that restricts the drive of the hydraulic actuator; and a controller that controls the switching valve. The controller includes: an operation signal acquisition unit configured to acquire the operation signal; and an instruction output unit configured to output, to the switching valve, a control instruction that restricts the drive of the hydraulic actuator with the engine driving, in response to the operation signal.

Abstract: A hemostatic device includes a band for wrapping around a puncture site of a wrist, a mechanism for securing the band to the wrist in a wrapped state, an inflatable portion connected to the band and inflated by being injected with air, a tube body that communicates between an inflatable space of the inflatable portion and an outside, and a cover portion that covers the tube body in the inflatable portion, in which the tube body has a hole portion that opens in the inflatable portion, the cover portion has a communication portion that is disposed to cover the hole portion and allows communication between the hole portion and the inflatable portion by being positioned to overlap the hole portion, and the tube body is movable relative to the cover portion so that a positional relation between the communication portion and the hole portion is controllable.

Abstract: A hemostatic device includes a band for wrapping around a puncture site of a wrist, a mechanism for securing the band to the wrist in a wrapped state, an inflatable portion connected to the band and inflated by being injected with gas, an injection part which is elastically transformable and is capable of injecting air into the inflatable portion, and a tube body that connects an inflatable space of the inflatable portion and a housing space of the injection part to each other, in which the tube body has a hole portion opening in the inflatable portion and a cover portion disposed on the tube body to cover the hole portion, and the cover portion has a communication portion that allows communication between the inflatable space and the housing space by air discharged from the hole portion when air is injected into the inflatable portion from the injection part.

Abstract: A work vehicle includes: a hydraulic pump driven by an engine; a hydraulic actuator that is driven by hydraulic oil supplied from the hydraulic pump; a switching valve configured to switch from one to the other of a first state in which the hydraulic oil supplied from the hydraulic pump is supplied to a first channel and a second state in which the hydraulic oil supplied from the hydraulic pump is supplied to a second channel; a restriction operation device configured to generate an operation signal that restricts the drive of the hydraulic actuator; and a controller that controls the switching valve. The controller includes: an operation signal acquisition unit configured to acquire the operation signal; and an instruction output unit configured to output, to the switching valve, a control instruction that restricts the drive of the hydraulic actuator with the engine driving, in response to the operation signal.

Abstract: A hemostatic device including a band that is wrapped around a limb of a living body at a site of the living body where bleeding is to be stopped and an inflatable portion which is inflated by injection of gas to cause the inflatable portion to press the site where bleeding is to be stopped. The hemostatic device includes an injection part that injects gas into the interior of the inflatable portion. The injection part includes a hole penetrating the injection part and communicating the housing space with outside environment. The hemostatic device includes a first support plate and a second support plate positioned adjacent one another along the longitudinal direction of the band. The second support plate is movably connected to the first support plate. The inflatable portion is on the first support plate and the injection part is on the second support plate.

Abstract: A puncture system that is configured to automatically puncture a radial artery of a hand of a patient includes: a grip to be gripped by the hand; a blood vessel detection unit that detects a position of an artery of the hand that grips the grip; an adjustment mechanism that adjusts a relative posture of the grip and a puncture needle a forward mechanism to move the puncture needle forward toward the grip; and a control unit that determines, in accordance with the position of the artery detected by the blood vessel detection unit, a relative posture of the grip and the puncture needle and a forward distance of the puncture needle, and controls operations of the adjustment mechanism and the forward mechanism on the basis of the posture and the forward distance having been determined.

Abstract: A hemostatic device has a band for being wrapped around a puncture site P of a wrist W, securing means for securing the band in a state where the band is wrapped around the wrist, an inflation portion that interlocks with the band, and that is inflated by injecting gas, and an injection portion that can inject gas into the inflation portion. The injection portion is disposed in the band, and is foldable so as to decrease a space formed inside the injection portion. The hemostatic device can thus inflate an inflation portion without using a separate dedicated instrument, which can prevent a hemostasis-requiring site from being unintentionally compressed more than necessary.

Abstract: A hemostatic device including a band that is wrapped around a limb of a living body at a site of the living body where bleeding is to be stopped and an inflatable portion which is inflated by injection of gas to cause the inflatable portion to press the site where bleeding is to be stopped. The hemostatic device includes an injection part that injects gas into the interior of the inflatable portion. The injection part includes a hole penetrating the injection part and communicating the housing space with outside environment. The hemostatic device includes a first support plate and a second support plate positioned adjacent one another along the longitudinal direction of the band. The second support plate is movably connected to the first support plate. The inflatable portion is on the first support plate and the injection part is on the second support plate.

Abstract: A hemostatic device includes a band for wrapping around a puncture site of a wrist , a mechanism for securing the band to the wrist in a wrapped state, an inflatable portion connected to the band and inflated by being injected with gas, an injection part which is elastically transformable and is capable of injecting air into the inflatable portion, and a tube body that connects an inflatable space of the inflatable portion and a housing space of the injection part to each other, in which the tube body has a hole portion opening in the inflatable portion and a cover portion disposed on the tube body to cover the hole portion, and the cover portion has a communication portion that allows communication between the inflatable space and the housing space by air discharged from the hole portion when air is injected into the inflatable portion from the injection part.

Abstract: A hemostatic device includes a band for wrapping around a puncture site of a wrist, a mechanism for securing the band to the wrist in a wrapped state, an inflatable portion connected to the band and inflated by being injected with air, a tube body that communicates between an inflatable space of the inflatable portion and an outside, and a cover portion that covers the tube body in the inflatable portion, in which the tube body has a hole portion that opens in the inflatable portion, the cover portion has a communication portion that is disposed to cover the hole portion and allows communication between the hole portion and the inflatable portion by being positioned to overlap the hole portion, and the tube body is movable relative to the cover portion so that a positional relation between the communication portion and the hole portion is controllable.

Abstract: A hemostatic device has a band for being wrapped around a puncture site P of a wrist W, securing means for securing the band in a state where the band is wrapped around the wrist, an inflation portion that interlocks with the band, and that is inflated by injecting gas, and an injection portion that can inject gas into the inflation portion. The injection portion is disposed in the band, and is foldable so as to decrease a space formed inside the injection portion. The hemostatic device can thus inflate an inflation portion without using a separate dedicated instrument, which can prevent a hemostasis-requiring site from being unintentionally compressed more than necessary.

Abstract: The present invention provides acetic anhydride, a method of purifying crude acetic anhydride, and a method of producing polyoxytetramethylene glycol using acetic anhydride. A method of producing polyoxytetramethylene glycol by ring-opening-polymerizing tetrahydrofuran in the presence of acetic anhydride and an acid catalyst, wherein said ring-opening polymerization is conducted using acetic anhydride having a diketene concentration of 10 ppm or less to produce polyoxytetramethylene glycol.

Abstract: The present invention provides acetic anhydride, a method of purifying crude acetic anhydride, and a method of producing polyoxytetramethylene glycol using acetic anhydride.