Abstract: A cell preparation for treating brain tumors used in combination with a prodrug that is converted to 5-fluorouracil by cytosine deaminase, wherein the cell preparation comprises neural stem cells derived from pluripotent stem cells having a cytosine deaminase gene and a uracil phosphoribosyltransferase gene is provided to establish new means for treating brain tumors.

Abstract: A front suspension device comprises a suspension arm, one end of which has a front-wheel support portion to support a front wheel of a vehicle and the other end of which is positioned on an inward side, in a vehicle width direction, of the front-wheel support portion and has a vehicle-body attachment portion to be attached to a vehicle-body member of the vehicle and a damper supported at a damper support portion which is provided at a portion of the suspension arm which is positioned in the vicinity of the front-wheel support portion at a lower portion thereof and connected to the vehicle-body member at an upper portion thereof. The damper support portion of the suspension arm has a breakage ease portion to cause breakage of the suspension arm.

Abstract: A steering system includes a column jacket that can extend and contract in an axial direction as a result of relative movement between an inner jacket and an outer jacket that houses the inner jacket, a regulation member fixed to the outer jacket and passing through an insertion hole in the inner jacket, and an elastic member fixed to the outer jacket. At the time of vehicular collision, when the regulation member is sheared by a peripheral portion of the insertion hole in the inner jacket in conjunction with the relative movement between the inner jacket and the outer jacket, a tip portion of the elastic member is fitted in the insertion hole.

Abstract: A steering system includes an upper jacket that is movable in an axial direction, a first stopper member fixed to the upper jacket, and a second stopper member on a vehicle body. When a lock and unlock mechanism unlocks the upper jacket, the second stopper member moves to an advanced position where the second stopper member faces the first stopper member in the axial direction. When the lock and unlock mechanism locks the upper jacket, the second stopper member moves to a retracted position where the second stopper member retracts from the advanced position.

Abstract: An outer jacket externally fitted over an inner jacket so as to be slidable in an axial direction relative to the inner jacket has a slit extending straight from an opening formed at a jacket end. A recessed portion is formed at an inner edge of the slit such that a slit width at an inside diameter portion of the outer jacket is larger than a slit width at an outside diameter portion of the outer jacket. An amount of recess of the recessed portion in a circumferential direction of the outer jacket continuously decreases from the opening end to an area end.

Abstract: A steering system includes an outer jacket including a pair of clamped portions disposed on both sides of a slit, an inner jacket coated with an insulating coating layer all along an outer periphery of the inner jacket except for a predetermined area, an upper bracket that supports the clamped portions and that is fixed to a vehicle body, and a clamping mechanism including a clamping shaft that is supported in clamping shaft insertion holes in the clamped portions so as to be energized. The steering system further includes a conductive elastic member including a first portion engaged with one of a slit inside portion of the clamping shaft positioned in the slit and the predetermined area so as to be energized and a second portion that slide-contacts the other of the slit inside portion and the predetermined area.

Abstract: A steering device includes: a rotary shaft supported by an upper bracket; a plurality of engaged teeth fixed to an upper jacket; a lock member including engaging teeth to mesh with the engaged teeth; and a support shaft supported by a lower jacket at a position farther away from the engaged teeth than the rotary shaft 35. When the rotary shaft is rotated, a first rotary member is rotated in synchronization with the rotary shaft. A second rotary member moves the lock member to a disengaged position in conjunction with rotation of the first rotary member. The lock member is urged toward a meshing position by an urging member.

Abstract: A fulcrum formation member forming a fulcrum and a first spring engagement portion are provided in a bracket. A lever link that swings about the fulcrum includes a second spring engagement portion forming a point of load, and an elongated hole in which a fastening shaft is fitted so as to be movable in a longitudinal direction in association with tilt adjustment. A point of effort is located at the edge of the elongated hole. One end of a spring member (biasing member) engages with the first spring engagement portion, and the other end thereof engages with the second spring engagement portion. The spring member biases a column jacket toward the upper side in a tilt direction via the lever link and the fastening shaft.

Abstract: A steering system includes an outer jacket including a pair of clamped portions disposed on both sides of a slit, an inner jacket coated with an insulating coating layer all along an outer periphery of the inner jacket except for a predetermined area, an upper bracket that supports the clamped portions and that is fixed to a vehicle body, and a clamping mechanism including a clamping shaft that is supported in clamping shaft insertion holes in the clamped portions so as to be energized. The steering system further includes a conductive elastic member including a first portion engaged with one of a slit inside portion of the clamping shaft positioned in the slit and the predetermined area so as to be energized and a second portion that slide-contacts the other of the slit inside portion and the predetermined area.

Abstract: A steering apparatus includes a first member which rotates together with an operation lever which is operated to rotate and a third member which is supported rotatably via a friction reducing mechanism by a second member which is restricted from rotating. A cam mechanism which brings a fixed side plate into press contact with a column side plate includes an axially facing surface which is provided on the first member and on which a cam surface is formed, an axially facing surface which is provided on the third member, rolling elements which are interposed between both the axially facing surfaces, and a retainer which holds the rolling elements and which is restricted from rotating by the second member.

Abstract: An outer jacket externally fitted over an inner jacket so as to be slidable in an axial direction relative to the inner jacket has a slit extending straight from an opening formed at a jacket end. A recessed portion is formed at an inner edge of the slit such that a slit width at an inside diameter portion of the outer jacket is larger than a slit width at an outside diameter portion of the outer jacket. An amount of recess of the recessed portion in a circumferential direction of the outer jacket continuously decreases from the opening end to an area end.

Abstract: A movable teeth row formed member is supported so as not only to move together with an operation shaft in a position adjusting direction but also to rotate around a pivot shaft which is parallel to the operation shaft in a first rotating direction and a second rotating direction. A lock biasing mechanism causes the movable teeth row formed member in the first rotating direction via an elastic member as an operation lever is operated to rotate in a locking direction, so that a movable teeth row is caused to move towards a fixed teeth row for meshing engagement with the fixed teeth row.

Abstract: A steering system includes an upper jacket that is movable in an axial direction, a first stopper member fixed to the upper jacket, and a second stopper member on a vehicle body. When a lock and unlock mechanism unlocks the upper jacket, the second stopper member moves to an advanced position where the second stopper member faces the first stopper member in the axial direction. When the lock and unlock mechanism locks the upper jacket, the second stopper member moves to a retracted position where the second stopper member retracts from the advanced position.

Abstract: A steering system includes a column jacket that can extend and contract in an axial direction as a result of relative movement between an inner jacket and an outer jacket that houses the inner jacket, a regulation member fixed to the outer jacket and passing through an insertion hole in the inner jacket, and an elastic member fixed to the outer jacket. At the time of vehicular collision, when the regulation member is sheared by a peripheral portion of the insertion hole in the inner jacket in conjunction with the relative movement between the inner jacket and the outer jacket, a tip portion of the elastic member is fitted in the insertion hole.

Abstract: Provided is a steering device including a hollow upper jacket that accommodates a steering shaft, a first engagement member, a rotary shaft that extends in a direction intersecting an axial direction of the steering shaft, and a second engagement member that is a component independent from the rotary shaft. The first engagement member has an engagement hole and is attached to the upper jacket. The second engagement member has an engagement projection which is engageable with the engagement hole. The second engagement member is movable between a lock position where the engagement projection engages with the engagement hole and a release position where the engagement projection is disengaged from the engagement hole, in accordance with a rotation of the rotary shaft. A vertical direction of the second engagement member between the lock position and the release position is different from a rotating direction of the rotary shaft.

Abstract: A steering apparatus includes a first member which rotates together with an operation lever which is operated to rotate and a third member which is supported rotatably via a friction reducing mechanism by a second member which is restricted from rotating. A cam mechanism which brings a fixed side plate into press contact with a column side plate includes an axially facing surface which is provided on the first member and on which a cam surface is formed, an axially facing surface which is provided on the third member, rolling elements which are interposed between both the axially facing surfaces, and a retainer which holds the rolling elements and which is restricted from rotating by the second member.

Abstract: A steering device includes: a rotary shaft supported by an upper bracket; a plurality of engaged teeth fixed to an upper jacket; a lock member including engaging teeth to mesh with the engaged teeth; and a support shaft supported by a lower jacket at a position farther away from the engaged teeth than the rotary shaft 35. When the rotary shaft is rotated, a first rotary member is rotated in synchronization with the rotary shaft. A second rotary member moves the lock member to a disengaged position in conjunction with rotation of the first rotary member. The lock member is urged toward a meshing position by an urging member.

Abstract: A stationary tooth row is provided in a restricted member that is not displaced together with a steering wheel during tilt adjustment of a steering system. A movable tooth row is provided in a movable member that is displaced in a tilt direction) together with the steering wheel during tilt adjustment. The movable tooth row includes a first movable tooth and second movable teeth. A first curvature radius of a tooth tip of the first movable tooth is made smaller than a second curvature radius of a tooth tip of each of the second movable teeth to make a tooth depth of the first movable tooth greater than a tooth depth of each of the second movable teeth.

Abstract: A stationary tooth row is provided in a restricted member that is not displaced together with a steering wheel during tilt adjustment of a steering system. A movable tooth row is provided in a movable member that is displaced in a tilt direction) together with the steering wheel during tilt adjustment. The movable tooth row includes a first movable tooth and second movable teeth. A first curvature radius of a tooth tip of the first movable tooth is made smaller than a second curvature radius of a tooth tip of each of the second movable teeth to make a tooth depth of the first movable tooth greater than a tooth depth of each of the second movable teeth.

Abstract: It is an object of the present invention to provide a steering apparatus for a vehicle mounting a steering lock device to an upper tube by small numbers of constructing parts. A guide supporting mechanism guiding and supporting a upper tube in relation to a lower housing along an axial direction of the upper tube includes a guide bracket portion fixed to the upper tube, and a guide portion mounted in the lower housing to guide and support the guide bracket along the axial direction of the guide tube. A steering lock device locking and unlocking rotation of the upper shaft includes a lock housing guiding a cylinder in back and forth direction, and a lock bracket portion mounted in a shape of grasping the upper tube by the lock housing therewith. The guide bracket and the lock bracket portion are formed to one piece as a whole.