Patents by Inventor Ryotaro Nakaya

Ryotaro Nakaya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220041648
    Abstract: Peptides may be continuously produced by a method including the following steps (1), (A), (2), and (B): (1) performing a condensation reaction in a flow reactor to obtain an N-protected C-protected peptide in which an N-terminal amino group and C-terminal are protected by protecting groups, a side chain functional group is optionally further protected by a protecting group, and at least one of the C-terminal or the side chain functional group is protected by a pseudo-solid-phase protecting group (N-protected C-protected peptide), (A) washing a reaction mixture containing an N-protected C-protected peptide in a flow reactor and separating oil and water to separate an organic layer containing the N-protected C-protected peptide, (2) subjecting an organic layer containing an N-protected C-protected peptide to a reaction to remove a protecting group of an N-terminal amino group in a flow reactor to obtain a C-protected peptide in which an N-terminal amino group is not protected, C-terminal is protected by a pr
    Type: Application
    Filed: October 21, 2021
    Publication date: February 10, 2022
    Applicant: AJINOMOTO CO., INC.
    Inventors: Daisuke TAKAHASHI, Metten BERT, Kimio KAWAJIRI, Ryotaro NAKAYA
  • Patent number: 9458289
    Abstract: Polyester compounds obtained by reaction of a compound represented by formula (1): (defined herein) with a compound represented by formula (2): (defined herein) exhibit high thermal resistance.
    Type: Grant
    Filed: October 1, 2015
    Date of Patent: October 4, 2016
    Assignee: Ajinomoto Co., Inc.
    Inventors: Fumi Shozui, Ryotaro Nakaya, Takashi Ineyama, Keiichi Yokoyama
  • Patent number: 9458288
    Abstract: Polyester compounds obtained by reaction of a compound represented by formula (1): (defined herein) with a compound represented by formula (2): (defined herein) exhibit high thermal resistance.
    Type: Grant
    Filed: October 1, 2015
    Date of Patent: October 4, 2016
    Assignee: Ajinomoto Co., Inc.
    Inventors: Fumi Shozui, Ryotaro Nakaya, Takashi Ineyama, Keiichi Yokoyama
  • Publication number: 20160237215
    Abstract: Polyamide compounds obtained by reacting a compound represented by formula (1): with a compound represented by formula (2): where the variables are described herein exhibit excellent heat resistance.
    Type: Application
    Filed: April 22, 2016
    Publication date: August 18, 2016
    Applicant: Ajinomoto Co., Inc.
    Inventors: Ryotaro NAKAYA, Fumi OGATA, Takashi INEYAMA, Keiichi YOKOYAMA
  • Patent number: 9371353
    Abstract: The present invention provides a protected nucleotide for elongation, which can be purified efficiently and in a high yield by a liquid-liquid extraction operation, and can achieve an oligonucleotide production method by a phosphoramidite method. It has been found that the above-mentioned problem can be solved by a particular oligonucleotide comprising a protected base and/or particular oligonucleotide protected by a branched chain-containing aromatic group at 3?-position.
    Type: Grant
    Filed: September 19, 2014
    Date of Patent: June 21, 2016
    Assignee: AJINOMOTO CO., INC.
    Inventors: Kunihiro Hirai, Satoshi Katayama, Takayoshi Torii, Ryotaro Nakaya, Daisuke Takahashi
  • Publication number: 20160024248
    Abstract: Polyester compounds obtained by reaction of a compound represented by formula (1): (defined herein) with a compound represented by formula (2): (defined herein) exhibit high thermal resistance.
    Type: Application
    Filed: October 1, 2015
    Publication date: January 28, 2016
    Applicant: Ajinomoto Co., Inc.
    Inventors: Fumi SHOZUI, Ryotaro NAKAYA, Takashi INEYAMA, Keiichi YOKOYAMA
  • Publication number: 20160024247
    Abstract: Polyester compounds obtained by reaction of a compound represented by formula (1): (defined herein) with a compound represented by formula (2): (defined herein) exhibit high thermal resistance.
    Type: Application
    Filed: October 1, 2015
    Publication date: January 28, 2016
    Applicant: Ajinomoto Co., Inc.
    Inventors: Fumi SHOZUI, Ryotaro NAKAYA, Takashi INEYAMA, Keiichi YOKOYAMA
  • Publication number: 20150080565
    Abstract: The present invention provides a protected nucleotide for elongation, which can be purified efficiently and in a high yield by a liquid-liquid extraction operation, and can achieve an oligonucleotide production method by a phosphoramidite method. It has been found that the above-mentioned problem can be solved by a particular oligonucleotide comprising a protected base and/or particular oligonucleotide protected by a branched chain-containing aromatic group at 3?-position.
    Type: Application
    Filed: September 19, 2014
    Publication date: March 19, 2015
    Applicant: Ajinomoto Co., Inc.
    Inventors: Kunihiro HIRAI, Satoshi Katayama, Takayoshi Torii, Ryotaro Nakaya, Daisuke Takahashi
  • Patent number: 8846885
    Abstract: The present invention provides a protected nucleotide for elongation, which can be purified efficiently and in a high yield by a liquid-liquid extraction operation, and can achieve an oligonucleotide production method by a phosphoramidite method. It has been found that the above-mentioned problem can be solved by a particular oligonucleotide comprising a protected base and/or particular oligonucleotide protected by a branched chain-containing aromatic group at 3?-position.
    Type: Grant
    Filed: February 15, 2013
    Date of Patent: September 30, 2014
    Assignee: Ajinomoto Co., Inc.
    Inventors: Kunihiro Hirai, Satoshi Katayama, Takayoshi Torii, Ryotaro Nakaya, Daisuke Takahashi
  • Publication number: 20130267697
    Abstract: The present invention provides a protected nucleotide for elongation, which can be purified efficiently and in a high yield by a liquid-liquid extraction operation, and can achieve an oligonucleotide production method by a phosphoramidite method. It has been found that the above-mentioned problem can be solved by a particular oligonucleotide comprising a protected base and/or particular oligonucleotide protected by a branched chain-containing aromatic group at 3?-position.
    Type: Application
    Filed: February 15, 2013
    Publication date: October 10, 2013
    Inventors: Kunihiro Hirai, Satoshi Katayama, Takayoshi Torii, Ryotaro Nakaya, Daisuke Takahashi