Patents by Inventor Ryozo Sakoda

Ryozo Sakoda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antiatherosclerotic agent compositions
    Patent number: 4719209
    Abstract: 3,5-Dimethyl-4,6-diphenyl-tetrahydro-2H-1,3,5-thiadiazine-2-thione having the formula: ##STR1## for use as an active therapeutic agent.
    Type: Grant
    Filed: July 2, 1986
    Date of Patent: January 12, 1988
    Assignee: Nissan Chemical Industries Ltd.
    Inventors: Tadashi Sasaki, Yoshihiro Fujikawa, Ryozo Sakoda, Mitsuaki Sakashita, Morihide Hibi
  • Method for treating atherosclerosis hyperlipidema, lipid deposition on arterial walls, or raising the ratio of high density lipoprotein cholesterol to total cholesterol in serum
    Patent number: 4624950
    Abstract: 3,5-Dimethyl-4,6-diphenyl-tetrahydro-2H-1,3,5-thiadiazine-2-thione having the formula: ##STR1## as an antiatherosclerotic agent.
    Type: Grant
    Filed: August 13, 1984
    Date of Patent: November 25, 1986
    Assignee: Nissan Chemical Industries Ltd.
    Inventors: Tadashi Sasaki, Yoshihiro Fujikawa, Ryozo Sakoda, Mitsuaki Sakashita, Morihide Hibi
  • Antihypertensive dihydropyridine-5-phosphonic acid cyclic esters
    Patent number: 4576934
    Abstract: A compound of the formula: ##STR1## where X is hydrogen, nitro, trifluoromethyl, fluorine, chlorine, bromine or iodine; A is 1,3-propylene or 1,4-butylene which may be substituted by C.sub.1 -C.sub.3 alkyl, R is C.sub.1 -C.sub.4 alkyl, --Y--N(R.sup.1)(R.sup.2) or ##STR2## where each of R.sup.1, R.sup.2 and R.sup.3, which may be the same or different are hydrogen, C.sub.1 -C.sub.6 alkyl, or aralkyl, and Y is C.sub.2 -C.sub.6 alkylene, and Me is methyl, or its pharmaceutically acceptable salt. These compounds have utility as anti-hypertensive agents and coronary or peripheral vasodilators.
    Type: Grant
    Filed: September 26, 1984
    Date of Patent: March 18, 1986
    Assignee: Nissan Chemical Industries Ltd.
    Inventors: Kiyotomo Seto, Sakuya Tanaka, Ryozo Sakoda
  • O-(N-Allyl-2,6-dichloroanilino)phenylacetic acid derivative and a process for preparing the same
    Patent number: 4242522
    Abstract: An o-(N-allyl-2,6-dichloroanilino)phenylacetic acid derivative represented by the formula: ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3, which may be the same or different, individually represent a hydrogen atom, a halogen atom or an alkyl group; Y represents a hydroxyl group, an alkoxyl group, a --OM.sup.1 group in which M.sup.1 is an alkali metal atom, a --OM.sub.1/2.sup.2 group in which M.sup.2 is an alkaline earth metal atom, an amino group having the formula --NR.sup.5 R.sup.6 in which R.sup.5 and R.sup.6, which may be the same or different, individually represent a hydrogen atom or an alkyl group, or a hydroxylamino group,and processes for preparing the same.
    Type: Grant
    Filed: September 17, 1979
    Date of Patent: December 30, 1980
    Assignees: Nissan Chemical Industries, Ltd., Sagami Chemical Research Center
    Inventors: Genichi Tsuchihashi, Katsuyuki Ogura, Ryozo Sakoda, Isao Hashiba, Shuichi Fukushima
  • [N-benzyl-o-(2,6-dichloroanilino)phenyl]acetic acid derivatives
    Patent number: 4189595
    Abstract: Novel compounds of [N-benzyl-o-(2,6-dichloroanilino)phenyl]acetic acid derivatives having the formula ##STR1## wherein X represents H, Cl, Br or a C.sub.1 -C.sub.4 alkyl group and Y is OH, OR or SR and R represents a C.sub.1 -C.sub.4 alkyl group.
    Type: Grant
    Filed: August 30, 1978
    Date of Patent: February 19, 1980
    Assignees: Nissan Chemical Industries, Ltd., Sagami Chemical Research Center
    Inventors: Ryozo Sakoda, Kazuo Nagano, Yumiko Ando, Genichi Tsuchihashi, Katsuyuki Ogura
  • Process for preparing anthranylaldehyde derivatives
    Patent number: 4188343
    Abstract: Improved process for preparing anthranylaldehyde derivatives of formula: ##STR1## (Z.sup.1 and Z.sup.2 each represents hydrogen atom, a halogen atom, methyl group or trifluoromethyl group.) is provided.The process comprises steps of (1) protecting aldehyde group of a o-halogenobenzaldehyde with a specific alkylamine derivative, then (2) reacting the thus protected compound with a corresponding aniline derivative, and finally, (3) treating the thus obtained product with an acid.The anthranylaldehyde derivatives, i.a. N-(2,6-dichlorophenyl)anthranylaldehyde is useful as an intermediate for preparation of the corresponding anilinophenylacetic acids which are anti-inflammatory and analgesic agents.
    Type: Grant
    Filed: December 27, 1978
    Date of Patent: February 12, 1980
    Assignee: Nissan Chemical Industries, Ltd.
    Inventors: Ryozo Sakoda, Isao Hashiba, Kazuo Nagano