Patents by Inventor Ryozo Watanabe
Ryozo Watanabe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 6331324Abstract: A soybean curd puree which can be applied to various foods and are useful for expansion of applications of soybean milk, and a process and apparatus for preparing the same, and the apparatus includes a system in which a raw material tank, heating apparatus, a holding pipe, first emulsifying dispersion apparatus, cooling apparatus and second emulsifying dispersion apparatus are arranged in that order, and coagulant supply apparatus connected between the heating apparatus and the holding pipe, and the process includes adding the coagulant to the soy milk, holding the temperature thereof at 40 to 90° C. to form a coagulated product, pre-crushing the product by the first emulsifying dispersion apparatus, followed by cooling to 10 to 35° C., and crushing the product by the second emulsifying dispersion apparatus into particles having the average particle diameter of 2 to 15 &mgr;m and 90% particles diameter of not more than 35 &mgr;m.Type: GrantFiled: July 14, 2000Date of Patent: December 18, 2001Assignee: Morinaga Milk Industry Co., Ltd.Inventors: Mamoru Tomita, Kazuyoshi Sotoyama, Ryozo Watanabe, Kenji Mizuguchi, Hideo Shidara, Shoji Wakao, Masanori Hattori, Nobuyuki Motoyoshi
-
Patent number: 4476093Abstract: A method for preparing a sample for use in endotoxin test which comprises subjecting a sample of plasma or blood preparation to a contact with water-insoluble anti human .alpha..sub.2 -macroglobulin antibody and to a gel filtration by means of a gel of allyl dextran crosslinked with N,N'-methylenebis acrylamide or a gel of polyvinyl alcohol having many hydrophilic hydroxyl groups, and recovering the maximum molecular weight fraction.A kit for preparing a sample for use in the endotoxin test consisting of a set of a sample-developing column prepared by packing a water-insoluble anti-human .alpha..sub.2 -macroglobulin antibody and a gel of allyl dextran crosslinked with N,N'-methylenebis acrylamide or a gel of polyvinyl alcohol having many hydrophilic hydroxyl groups, both equilibrated with a buffer solution of pH 7.0-7.Type: GrantFiled: April 28, 1983Date of Patent: October 9, 1984Assignee: The Green Cross CorporationInventors: Ryozo Watanabe, Keiichi Kawasumi, Shoichi Maeda, Takashi Shoji
-
Patent number: 4414336Abstract: (1) A method for preparing a sample for use in the endotoxin test which comprises subjecting a sample of plasma or blood preparation to a contact with water-insoluble anti-human .alpha..sub.2 -macroglobulin antibody and to a gel filtration by means of a gel of allyl dextran crosslinked with N,N'-methylenebis acrylamide or a gel of polyvinyl alcohol having many hydrophilic hydroxyl groups, and recovering the maximum molecular weight fraction.(2) A kit for preparing a sample for use in the endotoxin test consisting of a set of a sample-developing column prepared by packing a water-insoluble anti-human .alpha..sub.2 -macroglobulin antibody and a gel of allyl dextran crosslinked with N,N'-methylenebis acrylamide or a gel of polyvinyl alcohol having many hydrophilic hydroxyl groups, both equilibrated with a buffer solution of pH 7.0-7.Type: GrantFiled: September 29, 1981Date of Patent: November 8, 1983Assignee: The Green Cross CorporationInventors: Ryozo Watanabe, Keiichi Kawasumi, Shoichi Maeda, Takashi Shoji
-
Patent number: 4361653Abstract: A plasminogen preparation comprising a plasminogen-containing aqueous solution or of plasminogen dry powder each admixed with at least one of lysine, phenylmethanesulfonyl fluoride, aprotinin, and soybean trypsin inhibitor in an effective amount for stabilizing plasminogen.Type: GrantFiled: January 16, 1981Date of Patent: November 30, 1982Assignee: The Green Cross CorporationInventors: Ryozo Watanabe, Mitsuomi Ohgaki
-
Patent number: 4265888Abstract: Acetylsalicylates with basic amino acids such as DL-lysine is stabilized in the form of solid preparation by admixing anhydrous calcium chloride therewith. The preparation containing calcium chloride is prevented from hydrolysis and can be stored for a long period of time even at a relatively high room temperature. The preparation is further prevented from discarolation when glycine is added thereto.Type: GrantFiled: January 8, 1980Date of Patent: May 5, 1981Assignee: The Green Cross CorporationInventors: Yoshio Kagitani, Takashi Imagawa, Hirohisa Inahara, Ryozo Watanabe
-
Patent number: 3993581Abstract: Oxygen-transferable perfluorocarbon compounds having 9 to 11 carbon atoms such as perfluorodecalin, perfluoro(C.sub.3.sub.-5 -alkylcyclohexanes), perfluoro(C.sub.4.sub.-6 -alkyl tetrahydropyrans), perfluoro(C.sub.5.sub.-7 -alkyltetrahydrofurans), perfluoro(C.sub.5.sub.-7 -alkylmorpholins) and perfluoro(C.sub.9.sub.-11 -trialkylamines) are emulsified in a physiologically acceptable aqueous solution such as Ringer's solution by the aid of a phospholipid as emulsifier and a fatty acid of 8 to 22 carbon atoms, alkali metal salt or monoglyceride thereof as emulsifying adjuvant. The emulsion is stable for a considerable period of time and contains particles having a particle size ranging from 0.05 to 0.3 .mu.. It is usable as a blood substitute or a perfurate for preservation of the internal organs.Type: GrantFiled: July 2, 1974Date of Patent: November 23, 1976Assignee: The Green Cross CorporationInventors: Kazumasa Yokoyama, Koichi Yamanouchi, Ryoichiro Murashima, Ryozo Watanabe
-
Patent number: 3962439Abstract: Oxygen-transferable perfluorocarbon compounds having 9 to 11 carbon atoms such as perfluorodecalin, perfluoro(C.sub.3-5 -alkylcyclohexanes), perfluoro(C.sub.4-6 -alkyl tetrahydropyrans), perfluoro(C.sub.5-7 -alkyltetrahydrofurans), perfluoro(C.sub.5-7 -alkylmorpholins) and perfluoro(C.sub.9-11 -trialkylamines) are emulsified in a physiologically acceptable aqueons solution such as Ringer's solution by the aid of a phospholipid as emulsifier and a fatty acid of 8 to 22 carbon atoms, alkali metal salt or monoglyceride thereof as emulsifying adjuvant. The emulsion is stable for a considerable period of time and contains particles having a particle size ranging from 0.05 to 0.3 .mu.. It is usable as a blood substitute or a perfusate for preservation of the internal organs.Type: GrantFiled: February 4, 1974Date of Patent: June 8, 1976Assignee: The Green Cross CorporationInventors: Kazumasa Yokoyama, Koichi Yamanouchi, Ryoichiro Murashima, Ryozo Watanabe
-
Patent number: 3958014Abstract: An injectable fluorocarbon emulsion capable of carrying oxygen, which can be used as artificial blood and organ perfusate, is prepared by emulsifying a fluorocarbon, having an ability to dissolve at least 30 V/V % of oxygen under a 100% oxygen atmosphere at an atmospheric pressure, in an aqueous salt solution with a surfactant, centrifuging the resulting aqueous emulsion thereby to reduce the fluorocarbon particles in the emulsion in size to particle sizes of the order of about 0.05 to 0.25 .mu., and then sterilizing the thus obtained emulsion under rotation. The resulting fluorocarbon emulsion can be used as an emergency blood substitute for transfusion.Type: GrantFiled: March 20, 1973Date of Patent: May 18, 1976Assignees: The Green Cross Corporation, Tanabe Seiyaku Co., Ltd.Inventors: Ryozo Watanabe, Tadakazu Suyama, Kazumasa Yokoyama, Yohei Odaka