Patents by Inventor Ryuhei Shimizu

Ryuhei Shimizu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11422128
    Abstract: Regardless of the type of specimen, such as a serum or heparinized plasma containing different anticoagulants, which are widely used in general, when a substance to be measured (for example, sIL-2R) in a biological sample is immunologically detected, a measuring method and a kit capable of stably obtaining with high accuracy, unaffected by interfering substances in the specimen, are provided. An immunocomplex between the substance to be measured and an antibody that specifically binds to the substance to be measured is formed in the presence of a sulfated polysaccharide. The kit comprises an antibody that specifically binds to the substance to be measured, and a buffer containing a sulfated polysaccharide.
    Type: Grant
    Filed: April 12, 2017
    Date of Patent: August 23, 2022
    Assignee: LSI MEDIENCE CORPORATION
    Inventors: Ryuhei Shimizu, Keiichi Shoji, Xu Zhang
  • Publication number: 20190145965
    Abstract: Regardless of the type of specimen, such as a serum or heparinized plasma containing different anticoagulants, which are widely used in general, when a substance to be measured (for example, sIL-2R) in a biological sample is immunologically detected, a measuring method and a kit capable of stably obtaining with high accuracy, unaffected by interfering substances in the specimen, are provided. An immunocomplex between the substance to be measured and an antibody that specifically binds to the substance to be measured is formed in the presence of a sulfated polysaccharide. The kit comprises an antibody that specifically binds to the substance to be measured, and a buffer containing a sulfated polysaccharide.
    Type: Application
    Filed: April 12, 2017
    Publication date: May 16, 2019
    Applicant: LSI Medience Corporation
    Inventors: Ryuhei SHIMIZU, Keiichi SHOJI, Xu ZHANG
  • Patent number: 6689246
    Abstract: A box-structure airfoil is constructed of a composite material uppers skin, a composite material lower a skin 12 and a spar. Ribs and an elongate projection are formed integrally on the inner surface of each of the two skins. The upper and lower skins and the spar are simultaneously bonded by an adhesive to form a single structure. Since the ribs and the elongate projection are one-piece formed with each skin, it is possible to reduce the number of principal constituent components. Furthermore, since assembly operation is made by using the adhesive, there is no need for fasteners or the like for assembling. Moreover, the flanges on both sides of the spar can also be bonded to the respective skins. According to the invention, it is possible to reduce the number of principal constituent components and that of assembling components of an airfoil, thereby achieving its cost reduction.
    Type: Grant
    Filed: April 4, 2001
    Date of Patent: February 10, 2004
    Assignee: Japan Aircraft Development Corporation
    Inventors: Makoto Hirahara, Yasuo Isano, Ryuhei Shimizu, Kazuaki Amaoka
  • Publication number: 20010017336
    Abstract: A box-structure airfoil is constructed of a composite material upper skin, a composite material lower skin 12 and a spar. Ribs and an elongate projection are formed integrally on the inner surface of each of the two skins. The upper and lower skins and the spar are simultaneously bonded by an adhesive to form a single structure. Since the ribs and the elongate projection are one-piece formed with each skin, it is possible to reduce the number of principal constituent components. Furthermore, since assembly operation is made by using the adhesive, there is no need for fasteners or the like for assembling. Moreover, the spar is bonded not only to Moreover, because not only a web but also flanges on both sides of the spar are bonded to the respective skins, it is possible to obtain a large strength. According to the invention, it is possible to reduce the number of principal constituent components and that of assembling components of an airfoil, thereby achieving its cost reduction.
    Type: Application
    Filed: April 4, 2001
    Publication date: August 30, 2001
    Inventors: Makoto Hirahara, Yasuo Isano, Ryuhei Shimizu, Kazuaki Amaoka
  • Patent number: 6234423
    Abstract: A box-structure airfoil is constructed of a composite material upper skin, a composite material lower skin 12 and a spar. Ribs and an elongate projection are formed integrally on the inner surface of each of the two skins. The upper and lower skins and the spar are simultaneously bonded by an adhesive to form a single structure. Since the ribs and the elongate projection are one-piece formed with each skin, it is possible to reduce the number of principal constituent components. Furthermore, since assembly operation is made by using the adhesive, there is no need for fasteners or the like for assembling. Moreover, the spar is bonded not only to Moreover, because not only a web but also flanges on both sides of the spar are bonded to the respective skins, it is possible to obtain a large strength. According to the invention, it is possible to reduce the number of principal constituent components and that of assembling components of an airfoil, thereby achieving its cost reduction.
    Type: Grant
    Filed: July 29, 1999
    Date of Patent: May 22, 2001
    Assignee: Japan Aircraft Development Corporation
    Inventors: Makoto Hirahara, Yasuo Isano, Ryuhei Shimizu, Kazuaki Amaoka