Patents by Inventor Ryuichi Kiyama

Ryuichi Kiyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIVIRAL AGENT
    Publication number: 20170066754
    Abstract: The present invention provides an integrase inhibitor. The inventors have found the following compound of formula (I) possessing an integrase inhibitory activity. (wherein, RC and RD taken together with the neighboring carbon atoms form a ring which may be a condensed ring, Y is hydroxyl, mercapto or amino; Z is O, S or NH; RA is a group shown by (wherein, C ring is N-containing aromatic heterocycle) or the like).
    Type: Application
    Filed: November 18, 2016
    Publication date: March 9, 2017
    Applicant: SHIONOGI & CO., LTD.
    Inventors: Ryuichi KIYAMA, Yasuhiko KANDA, Yukio TADA, Toshio FUJISHITA, Takashi KAWASUJI, Shozo TAKECHI, Masahiro FUJI
  • Antiviral agent
    Patent number: 9572813
    Abstract: The present invention provides an integrase inhibitor. The inventors have found the following compound of formula (I) possessing an integrase inhibitory activity. (wherein, RC and RD taken together with the neighboring carbon atoms form a ring which may be a condensed ring, Y is hydroxyl, mercapto or amino; Z is O, S or NH; RA is a group shown by (wherein, C ring is N-containing aromatic heterocycle) or the like).
    Type: Grant
    Filed: January 23, 2015
    Date of Patent: February 21, 2017
    Assignee: Shionogi & Co., Ltd.
    Inventors: Ryuichi Kiyama, Yasuhiko Kanda, Yukio Tada, Toshio Fujishita, Takashi Kawasuji, Shozo Takechi, Masahiro Fuji
  • ANTIVIRAL AGENT
    Publication number: 20150202208
    Abstract: The present invention provides an integrase inhibitor. The inventors have found the following compound of formula (I) possessing an integrase inhibitory activity. (wherein, RC and RD taken together with the neighboring carbon atoms form a ring which may be a condensed ring, Y is hydroxyl, mercapto or amino; Z is O, S or NH; RA is a group shown by (wherein, C ring is N-containing aromatic heterocycle) or the like).
    Type: Application
    Filed: January 23, 2015
    Publication date: July 23, 2015
    Inventors: Ryuichi KIYAMA, Yasuhiko KANDA, Yukio TADA, Toshio FUJISHITA, Takashi KAWASUJI, Shozo TAKECHI, Masahiro FUJI
  • Inhibitor for enzyme having two divalent metal ions as active center
    Publication number: 20100068695
    Abstract: A pharmaceutical composition for use as an inhibitor of an enzyme having two divalent metal ions as an active center was found. It is possible to inhibit the activity of an enzyme by a compound capable of chelating both of the two divalent metal ions.
    Type: Application
    Filed: July 27, 2009
    Publication date: March 18, 2010
    Inventors: Ryuichi Kiyama, Takashi Kawasuji
  • Antiviral agent
    Publication number: 20040229909
    Abstract: The present invention provides an integrase inhibitor. The inventors have have found the following compound of formula (I) possessing an integrase inhibitory activity.
    Type: Application
    Filed: January 30, 2004
    Publication date: November 18, 2004
    Inventors: Ryuichi Kiyama, Yasuhiko Kanda, Yukio Tada, Toshio Fujishita, Takashi Kawasuji, Shozo Takechi, Masahiro Fuji
  • Inhibitor for enzyme having two divalent metal ions as active centers
    Publication number: 20040039060
    Abstract: A pharmaceutical composition for use as an inhibitor of an enzyme having two divalent metal ions as an active center was found.
    Type: Application
    Filed: December 13, 2002
    Publication date: February 26, 2004
    Inventors: Ryuichi Kiyama, Takashi Kawasuji