Patents by Inventor Ryuichi Morishita

Ryuichi Morishita has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10695420
    Abstract: The present invention provides a combination preparation for inducing a specific immune response to an antigenic peptide, which contains (I) the antigenic peptide, and (II) an expression vector encoding a chimeric hepatitis B virus core antigen polypeptide, into which the antigenic peptide has been inserted or added, wherein said antigenic peptide is inserted in a region of amino acid residues 74-87 or 130-138 of the hepatitis B virus core antigen polypeptide, or added to the N-terminal or C-terminal of the hepatitis B virus core antigen polypeptide, wherein the antigenic peptide of (I) and the expression vector of (II) are substantially simultaneously administered to a subject.
    Type: Grant
    Filed: November 20, 2015
    Date of Patent: June 30, 2020
    Assignees: ANGES, INC., OSAKA UNIVERSITY, DS PHARMA ANIMAL HEALTH CO., LTD.
    Inventors: Hironori Nakagami, Ryuichi Morishita, Hiroshi Koriyama, Hideki Tomioka, Kenji Naohara
  • Patent number: 10637124
    Abstract: The present invention provides a window glass near which an electronic device is disposed, the window glass including a glass plate, an antenna disposed on the glass plate, an electronic device that is disposed near the glass plate, and at least one linear canceller that is disposed on the glass plate and is configured to inhibit noise produced from the electronic device from being received by the antenna.
    Type: Grant
    Filed: October 19, 2017
    Date of Patent: April 28, 2020
    Assignee: NIPPON SHEET GLASS COMPANY, LIMITED
    Inventors: Hideshi Nagata, Takahiro Asai, Ryuichi Tashiro, Hiromasa Morishita
  • Publication number: 20200052366
    Abstract: The present invention provides a window glass near which an electronic device is disposed, the window glass including a glass plate, an antenna disposed on the glass plate, an electronic device that is disposed near the glass plate, and at least one linear canceller that is disposed on the glass plate and is configured to inhibit noise produced from the electronic device from being received by the antenna.
    Type: Application
    Filed: October 19, 2017
    Publication date: February 13, 2020
    Applicant: NIPPON SHEET GLASS COMPANY, LIMITED
    Inventors: Hideshi NAGATA, Takahiro ASAI, Ryuichi TASHIRO, Hiromasa MORISHITA
  • Patent number: 10543261
    Abstract: The present invention provides a therapeutic or prophylactic agent for cancer, containing an expression vector encoding a chimeric Hepatitis B virus core antigen polypeptide inserted with an amino acid sequence containing a specific epitope of VEGF and/or a specific epitope of angiopoietin-2, wherein the amino acid sequence containing the specific epitope is inserted between the amino acid residues 80 and 81 of the hepatitis B virus core antigen polypeptide.
    Type: Grant
    Filed: August 28, 2013
    Date of Patent: January 28, 2020
    Assignees: Osaka University, AnGes, Inc.
    Inventors: Hironori Nakagami, Mariko Kyutoku, Ryuichi Morishita, Hideki Tomioka
  • Publication number: 20200023045
    Abstract: Provided is an immunogenic composition comprising an antigenic peptide capable of inducing production of a neutralizing antibody against S100A9 and a carrier protein. The immunogenic composition can be used as a highly safe antithrombotic vaccine having antithrombotic effect without a long-term bleeding risk and is useful for the prevention of a disease associated with thrombus formation in which platelet aggregation is involved, particularly for the prevention of recurrent ischemic stroke.
    Type: Application
    Filed: February 20, 2018
    Publication date: January 23, 2020
    Applicants: OSAKA UNIVERSITY, FUNPEP CO., LTD.
    Inventors: Munehisa SHIMAMURA, Tomohiro KAWANO, Hironori NAKAGAMI, Ryuichi MORISHITA, Hideki MOCHIZUKI, Akiko TENMA, Takako EHARA
  • Patent number: 10517926
    Abstract: Provided is an oligopeptide having preventive and therapeutic effects on infarction diseases. The oligopeptide contains a DE loop sequence of RANKL protein, and has inhibitory activity on proinflammatory cytokine secretion from cells.
    Type: Grant
    Filed: May 16, 2016
    Date of Patent: December 31, 2019
    Assignee: Osaka University
    Inventors: Munehisa Shimamura, Hironori Nakagami, Hitomi Kurinami, Ryuichi Morishita
  • Publication number: 20190365859
    Abstract: The present invention provides a preventive or therapeutic agent for an inflammatory skin disease, such as psoriasis, the agent comprising an oligopeptide as an active ingredient. More specifically, the invention provides a preventive or therapeutic agent for an inflammatory skin disease, the agent comprising an oligopeptide consisting of an amino acid sequence containing a DE loop sequence of RANKL protein and a ?-strand D sequence of RANKL protein placed adjacent to the N-terminal side of the DE loop sequence.
    Type: Application
    Filed: November 7, 2017
    Publication date: December 5, 2019
    Inventors: Munehisa Shimamura, Hironori Nakagami, Yuka Ikeda, Ryuichi Morishita, Hiroshi Koriyama
  • Patent number: 10463592
    Abstract: An object of the present invention to discover a short peptide having an anti-aging effect and to provide a novel anti-aging agent comprising the peptide as an active ingredient. The inventors have discovered that a peptide consisting of an amino acid sequence ELKLIFLHRLKRLRKRLKRK (SEQ ID NO: 1) or a partial sequence thereof and having one or more effects selected from the group consisting of promoting fibroblast growth, promoting hyaluronic acid production and contracting a collagen gel, or a derivative or salt of the peptide is useful as an active ingredient of an anti-aging agent.
    Type: Grant
    Filed: December 7, 2017
    Date of Patent: November 5, 2019
    Assignee: Osaka University
    Inventors: Hironori Nakagami, Ryuichi Morishita, Hideki Tomioka, Akiko Tenma
  • Publication number: 20190321444
    Abstract: Described herein is the discovery that HGFs activate the growth and migration of lymphatic endothelial cells and thereby promote lymphangiogenesis. The present invention is based on this finding, and provides lymphangiogenesis-promoting agents comprising as active ingredients HGFs, or proteins or compounds functionally equivalent thereto. Based on the finding described above, the present invention also provides methods for promoting lymphangiogenesis which comprise the step of locally administering HGFs or proteins functionally equivalent thereto to affected areas in patients with lymphedema.
    Type: Application
    Filed: January 3, 2019
    Publication date: October 24, 2019
    Applicant: AnGes, Inc.
    Inventors: RYUICHI MORISHITA, Yasufumi Kaneda, Hironori Nakagami, Yukihiro Saito
  • Publication number: 20190106484
    Abstract: The present invention provides a drug for preventing or treating inflammation-associated diseases in which a periostin isoform having cell adhesion activity is involved, and also provides an inhibitor of a periostin isoform having cell adhesion activity.
    Type: Application
    Filed: October 23, 2018
    Publication date: April 11, 2019
    Applicant: OSAKA UNIVERSITY
    Inventors: Yoshiaki TANIYAMA, Ryuichi MORISHITA, Junya AZUMA, Fumihiro SANADA, Naruto KATSURAGI
  • Publication number: 20190105388
    Abstract: The present invention provides a vaccine containing a complex of a peptide consisting of the amino acid sequence of SEQ ID NO: 1 and an epitope of a disease-causing biological protein such as DPP4, IL-17A, IgE, S100A9 or PCSK9, which vaccine uses a less antigenic carrier protein and is capable of inducing antibody production to serve as an effective vaccine.
    Type: Application
    Filed: March 24, 2017
    Publication date: April 11, 2019
    Applicants: OSAKA UNIVERSITY, FUNPEP CO., LTD.
    Inventors: Hironori NAKAGAMI, Ryuichi MORISHITA, Akiko TENMA
  • Patent number: 10233215
    Abstract: The invention provides a peptide and an immunostimulant or hair grower containing the peptide as an active ingredient, as well as a method for hair growth or regrowth promotion by administering an effective amount of the peptide to a mammal. The peptide has 23 or less amino acids and includes the amino acid sequence LHRLKRLRKRL (SEQ ID NO: 1), preferably the amino acid sequence LHRLKRLRKRLK (SEQ ID NO: 9).
    Type: Grant
    Filed: September 18, 2018
    Date of Patent: March 19, 2019
    Assignee: OSAKA UNIVERSITY
    Inventors: Hironori Nakagami, Ryuichi Morishita, Hiroshi Koriyama, Akiko Tenma
  • Patent number: 10227396
    Abstract: The present invention provides a drug for preventing or treating inflammation-associated diseases in which a periostin isoform having cell adhesion activity is involved, and also provides an inhibitor of a periostin isoform having cell adhesion activity.
    Type: Grant
    Filed: March 6, 2014
    Date of Patent: March 12, 2019
    Assignee: OSAKA UNIVERSITY
    Inventors: Yoshiaki Taniyama, Ryuichi Morishita, Junya Azuma, Fumihiro Sanada, Naruto Katsuragi
  • Publication number: 20190002505
    Abstract: The invention provides a peptide and an immunostimulant or hair grower containing the peptide as an active ingredient, as well as a method for hair growth or regrowth promotion by administering an effective amount of the peptide to a mammal. The peptide has 23 or less amino acids and includes the amino acid sequence LHRLKRLRKRL (SEQ ID NO: 1), preferably the amino acid sequence LHRLKRLRKRLK (SEQ ID NO: 9).
    Type: Application
    Filed: September 18, 2018
    Publication date: January 3, 2019
    Applicant: OSAKA UNIVERSITY
    Inventors: Hironori Nakagami, Ryuichi Morishita, Hiroshi Koriyama, Akiko Tenma
  • Patent number: 10112978
    Abstract: An object of the present invention is to provide a novel peptide and a novel immunostimulant or hair grower containing the peptide as an active ingredient. The present invention provides a peptide of 23 or less amino acids comprising the amino acid sequence LHRLKRLRKRL (SEQ ID NO: 1), preferably the amino acid sequence LHRLKRLRKRLK (SEQ ID NO: 9), and also provides an immunostimulant containing the peptide, a vaccine adjuvant containing the peptide, a vaccine composition containing the peptide, and a hair grower containing the peptide.
    Type: Grant
    Filed: September 25, 2015
    Date of Patent: October 30, 2018
    Assignee: Osaka University
    Inventors: Hironori Nakagami, Ryuichi Morishita, Hiroshi Koriyama, Akiko Tenma
  • Publication number: 20180298381
    Abstract: Disclosed is a double-stranded oligonucleotide decoy including two transcription factor-binding sites, while keeping its size small. The double-stranded oligonucleotide decoy showing binding affinities for two transcription factors includes a first binding site for a first transcription factor and a second binding site for a second transcription factor. A first strand including the sense strand of the first binding site and a second strand including the sense strand of the second binding site are hybridized to form a double strand in which the sense strand of the first binding site and the sense strand of the second binding site are at least partly hybridized.
    Type: Application
    Filed: September 9, 2016
    Publication date: October 18, 2018
    Applicants: AnGes, Inc., GeneDesign, Inc.
    Inventors: Ryuichi MORISHITA, Takashi MIYAKE, Tetsuo MIYAKE, Takahiro NAKAZAWA, Makoto SAKAGUCHI, Satoshi INOUE, Ryoji UEKI
  • Publication number: 20180147259
    Abstract: Provided is an oligopeptide having preventive and therapeutic effects on infarction diseases. The oligopeptide contains a DE loop sequence of RANKL protein, and has inhibitory activity on proinflammatory cytokine secretion from cells.
    Type: Application
    Filed: May 16, 2016
    Publication date: May 31, 2018
    Inventors: Munehisa Shimamura, Hironori Nakagami, Hitomi Kurinami, Ryuichi Morishita
  • Publication number: 20180110713
    Abstract: An object of the present invention to discover a short peptide having an anti-aging effect and to provide a novel anti-aging agent comprising the peptide as an active ingredient. The inventors have discovered that a peptide consisting of an amino acid sequence ELKLIFLHRLKRLRKRLKRK (SEQ ID NO: 1) or a partial sequence thereof and having one or more effects selected from the group consisting of promoting fibroblast growth, promoting hyaluronic acid production and contracting a collagen gel, or a derivative or salt of the peptide is useful as an active ingredient of an anti-aging agent.
    Type: Application
    Filed: December 7, 2017
    Publication date: April 26, 2018
    Applicant: Osaka University
    Inventors: Hironori Nakagami, Ryuichi Morishita, Hideki Tomioka, Akiko Tenma
  • Patent number: 9913886
    Abstract: The present invention provides an agent for the treatment or prophylaxis of arteriosclerosis comprising an expression vector encoding a chimeric Hepatitis B virus core antigen polypeptide inserted with an amino acid sequence containing a specific epitope of apolipoprotein (a), wherein the amino acid sequence containing the specific epitope is inserted between the amino acid residues 80 and 81 of the hepatitis B virus core antigen polypeptide.
    Type: Grant
    Filed: July 1, 2016
    Date of Patent: March 13, 2018
    Assignee: AnGes, Inc.
    Inventors: Mariko Kyutoku, Hironori Nakagami, Hiroshi Koriyama, Futoshi Nakagami, Ryuichi Morishita
  • Patent number: 9889186
    Abstract: An oral preparation for the prophylaxis or treatment of a disease with infection by a pathogen, containing a killed lactic acid bacterium expressing, on the surface, an antigen of the pathogen, or a microparticulated form thereof, which has an average particle size of 2.68-30 ?m. An oral preparation for inducing cellular immunity to a target antigen, containing a killed lactic acid bacterium expressing the target antigen on the surface or a microparticulated form thereof, which has a particle size of 2.68-30 ?m.
    Type: Grant
    Filed: April 18, 2014
    Date of Patent: February 13, 2018
    Assignees: MORISHITA JINTAN CO., LTD., BIOLEADERS CORPORATION
    Inventors: Takashi Nomura, Akiko Temma, Takahiro Nakazawa, Ryuichi Morishita, Il-Han Lee