Patents by Inventor Ryusuke Aoyama
Ryusuke Aoyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10370684Abstract: The invention relates to a method for treating a solution containing a saccharide comprising a heat treatment step of heating the saccharide solution at a temperature of 100° C. or higher and 180° C. or lower and a reduction step of reacting a reducing agent with the saccharide solution heated in the heat treatment step, a method for producing a treated saccharide solution using the treatment method, a treated saccharide solution obtained through treatment by the treatment method, a method for producing an organic compound comprising an organic-matter production step of obtaining an organic compound by causing a microorganism capable of producing organic matter to act on an organic raw material containing the treated saccharide solution and a method for culturing a microorganism using the treated saccharide solution as a carbon source.Type: GrantFiled: September 13, 2016Date of Patent: August 6, 2019Assignee: Mitsubishi Chemical CorporationInventors: Kiminori Kawakami, Yasuyo Saito, Takanao Matsumoto, Ryusuke Aoyama, Shigeki Nitta, Masaru Utsunomiya
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Publication number: 20160376616Abstract: The invention relates to a method for treating a solution containing a saccharide comprising a heat treatment step of heating the saccharide solution at a temperature of 100° C. or higher and 180° C. or lower and a reduction step of reacting a reducing agent with the saccharide solution heated in the heat treatment step, a method for producing a treated saccharide solution using the treatment method, a treated saccharide solution obtained through treatment by the treatment method, a method for producing an organic compound comprising an organic-matter production step of obtaining an organic compound by causing a microorganism capable of producing organic matter to act on an organic raw material containing the treated saccharide solution and a method for culturing a microorganism using the treated saccharide solution as a carbon source.Type: ApplicationFiled: September 13, 2016Publication date: December 29, 2016Applicant: MITSUBISHI CHEMICAL CORPORATIONInventors: Kiminori KAWAKAMI, Yasuyo Saito, Takanao Matsumoto, Ryusuke Aoyama, Shigeki Nitta, Masaru Utsunomiya
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Publication number: 20140242652Abstract: A method for producing succinic acid comprising (A) a step of converting an organic raw material to succinic acid in the presence of a microorganism or a processed product thereof in an aqueous medium and (B) a step of recovering the succinic acid, the method being characterized in that (A) the step of converting an organic raw material to succinic acid comprises: (a1) a step of adjusting the concentration of a succinic acid alkali metal salt in the aqueous medium to 80 mM or more; and then, (a2) a step of adding ammonia and/or an ammonium salt in the aqueous medium.Type: ApplicationFiled: May 12, 2014Publication date: August 28, 2014Applicant: MITSUBISHI CHEMICAL CORPORATIONInventors: Shuichi YUNOMURA, Daisuke Kido, Ryusuke Aoyama, Makoto Murase
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Patent number: 7993888Abstract: Provided is a bacterium which is capable of producing an organic acid and is modified so as to have an enhanced 2-oxoglutarate dehydrogenase activity as compared with that of an unmodified strain. An organic acid such as succinic acid can be produced by culturing the bacterium.Type: GrantFiled: February 23, 2007Date of Patent: August 9, 2011Assignees: Mitsubishi Chemical Corporation, Ajinomoto Co., Inc.Inventors: Makoto Murase, Ryusuke Aoyama, Akiko Sakamoto, Sanae Sato, Madoka Yonekura, Shuichi Yunomura, Kenji Yamagishi, Keita Fukui, Chie Koseki, Jun Nakamura, Hiroyuki Kojima
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Patent number: 7763447Abstract: Succinic acid is produced by allowing a bacterium modified to enhance fumarate reductase activity or cell preparation thereof to react with an organic raw material in a reaction solution containing one of a carbonate ion, a bicarbonate ion, and carbon dioxide gas to generate succinic acid. More preferably, succinic acid is produced by allowing a bacterium modified to enhance activities of fumarate reductase and pyruvate carboxylase and decrease lactate dehydrogenase activity or cell preparation thereof to react with an organic raw material in a reaction solution containing one of a carbonate ion, a bicarbonate ion, and carbon dioxide gas to generate succinic acid. Succinic acid is obtained by collecting the produced succinic acid.Type: GrantFiled: February 28, 2006Date of Patent: July 27, 2010Assignee: Ajinomoto Co., Inc.Inventors: Makoto Murase, Ryusuke Aoyama, Miki Ikuta, Kenji Yamagishi, Mika Moriya, Jun Nakamura, Hiroyuki Kojima
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Patent number: 7563606Abstract: Non-amino organic acids such as succinic acid, malic acid and fumaric acid are produced by reacting bacterial cells or treated bacterial cells of a coryneform bacterium with an organic raw material in an aqueous medium containing magnesium carbonate and/or magnesium hydroxide, and a certain range of concentration of a monovalent cation, while maintaining the pH within a certain range without increasing the volume of the aqueous medium.Type: GrantFiled: March 16, 2006Date of Patent: July 21, 2009Assignees: Mitsubishi Chemical Corporation, Ajinomoto Co., Inc.Inventors: Ryusuke Aoyama, Makoto Murase, Kenji Yamagishi, Kiyohiko Nishi, Hiroyuki Kojima
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Publication number: 20090156779Abstract: Provided is a bacterium which is capable of producing an organic acid and is modified so as to have an enhanced 2-oxoglutarate dehydrogenase activity as compared with that of an unmodified strain. An organic acid such as succinic acid can be produced by culturing the bacterium.Type: ApplicationFiled: February 23, 2007Publication date: June 18, 2009Applicants: MITSUBISHI CHEMICAL CORPORATION, AJINOMOTO CO., INC.Inventors: Makoto Murase, Ryusuke Aoyama, Akiko Sakamoto, Sanae Sato, Madoka Yonekura, Shuichi Yunomura, Kenji Yamagishi, Keita Fukui, Chie Koseki, Jun Nakamura, Hiroyuki Kojima
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Publication number: 20070015264Abstract: Organic acid ammonium solution is produced by the steps of obtaining a fermentation broth containing organic acid magnesium by using an organic acid-producing microorganism in the presence of a magnesium compound, producing organic acid ammonium and a magnesium compound by subjecting the organic acid magnesium contained in the fermentation broth to salt-exchange using an ammonia compound, and separating the produced magnesium compound to obtain organic acid ammonium solution.Type: ApplicationFiled: May 8, 2006Publication date: January 18, 2007Applicants: MITSUBISHI CHEMICAL CORPORATION, AJINOMOTO CO., INCInventors: Atsushi Isotani, Hideo Ikeda, Kenji Yamagishi, Ryusuke Aoyama
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Publication number: 20060281156Abstract: Non-amino organic acids such as succinic acid, malic acid and fumaric acid are produced by reacting bacterial cells or treated bacterial cells of a coryneform bacterium with an organic raw material in an aqueous medium containing magnesium carbonate and/or magnesium hydroxide, and a certain range of concentration of a monovalent cation, while maintaining the pH within a certain range without increasing the volume of the aqueous medium.Type: ApplicationFiled: March 16, 2006Publication date: December 14, 2006Applicants: MITSUBISHI CHEMICAL CORPORATION, AJINOMOTO CO., INC.Inventors: Ryusuke Aoyama, Makoto Murase, Kenji Yamagishi, Kiyohiko Nishi, Hiroyuki Kojima
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Publication number: 20060205048Abstract: Succinic acid is produced by allowing a bacterium modified to enhance fumarate reductase activity or cell preparation thereof to react with an organic raw material in a reaction solution containing one of a carbonate ion, a bicarbonate ion, and carbon dioxide gas to generate succinic acid. More preferably, succinic acid is produced by allowing a bacterium modified to enhance activities of fumarate reductase and pyruvate carboxylase and decrease lactate dehydrogenase activity or cell preparation thereof to react with an organic raw material in a reaction solution containing one of a carbonate ion, a bicarbonate ion, and carbon dioxide gas to generate succinic acid. Succinic acid is obtained by collecting the produced succinic acid.Type: ApplicationFiled: February 28, 2006Publication date: September 14, 2006Applicants: Mitsubishi Chemical Corporation, Ajinomoto Co. Inc.,Inventors: Makoto Murase, Ryusuke Aoyama, Miki Ikuta, Kenji Yamagishi, Mika Moriya, Jun Nakamura, Hiroyuki Kojima
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Publication number: 20020195463Abstract: In order to be capable of handling quantitatively a liquid in a simple structure by only easy operations, a control mechanism comprises a first flow channel and a second flow channel each extending along a predetermined direction; and a third flow channel having a thinner thickness than that of the first flow channel and that of the second flow channel; the above-described third flow channel being opened on flow channel walls of the first flow channel and the second flow channel, respectively, whereby the third flow channel links the first flow channel to the second flow channel; a liquid introduced into the first flow channel being pulled in the third flow channel due to a capillary phenomenon through an opening of the third flow channel opened on the flow channel wall of the first flow channel, and then, the liquid remained in the first flow channel being removed to prepare a droplet having a volume corresponding to a capacity of the third flow channel.Type: ApplicationFiled: May 30, 2002Publication date: December 26, 2002Inventors: Minoru Seki, Ryusuke Aoyama, Jong Wook Hong, Teruo Fujii, Isao Endo