Patents by Inventor S. Alan Harrison

S. Alan Harrison has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and apparatus for automatically detecting malignancy-associated changes
    Patent number: 6493460
    Abstract: A method for detecting malignancy-associated changes. A sample of cells is obtained and stained to identify the nuclear DNA material. The sample is imaged with a digital microscope. Objects of interest are identified in the sample of cells based on the intensity of the pixels that comprise the object versus the average intensity of all pixels in the slide image. An exact edge is located for each object and variations in the illumination intensity of the microscope are compensated for. A computer system calculates feature values for each object and, based on the value of the features, a determination is made whether the cell exhibits malignancy-associated changes or not.
    Type: Grant
    Filed: March 26, 1999
    Date of Patent: December 10, 2002
    Assignee: MonoGen, Inc.
    Inventors: Calum E. MacAulay, Branko Palcic, David M. Garner, S. Alan Harrison, Bruno W. Jaggi
  • System and method for automatically detecting malignant cells and cells having malignancy-associated changes
    Patent number: 6026174
    Abstract: A system and method for detecting diagnostic cells and cells having malignancy-associated changes are disclosed. The system includes an automated classifier having a microscope, camera, image digitizer, a computer system for controlling and interfacing these components, a primary classifier for initial cell classification, and a secondary classifier for subsequent cell classification. The method utilizes the automated classifier to automatically detect diagnostic cells and cells having malignancy-associated changes. The system and method are particularly useful for detecting these cells in cell samples obtained from bronchial specimens such as lung sputum.
    Type: Grant
    Filed: August 8, 1997
    Date of Patent: February 15, 2000
    Assignee: AccuMed International, Inc.
    Inventors: Branko Palcic, Calum Eric MacAulay, S. Alan Harrison, Stephen Lam, Peter William Payne, David Michael Garner, Alexei Doudkine
  • Method and apparatus for automatically detecting malignancy-associated changes
    Patent number: 5889881
    Abstract: A method for detecting malignancy-associated changes. A sample of cells is obtained and stained to identify the nuclear DNA material. The sample is imaged with a digital microscope. Objects of interest are identified in the sample of cells based on the intensity of the pixels that comprise the object versus the average intensity of all pixels in the slide image. An exact edge is located for each object and variations in the illumination intensity of the microscope are compensated for. A computer system calculates feature values for each object and, based on the value of the features, a determination is made whether the cell exhibits malignancy-associated changes or not.
    Type: Grant
    Filed: May 10, 1996
    Date of Patent: March 30, 1999
    Assignee: Oncometrics Imaging Corp.
    Inventors: Calum E. MacAulay, Branko Palcic, David M. Garner, S. Alan Harrison, Bruno W. Jaggi