Abstract: Biodegradable controlled release agent implants and methods of making and using thereof, are preferably formed of poly(?-pentadecalactone-co-p-dioxanone) [poly(PDL-co-DO)] or poly(ethylene brassylate-co-dioxanone), a family of polyester copolymers that degrade slowly in the presence of water. The material is suitable as the basis of a biodegradable controlled agent release implant that provides sustained release of a therapeutic such as an antiviral, thereby significantly increasing patent compliance and efficacy. Results show long term co-administration of agents having greater than additive efficacy. The implant may be inserted subcutaneously, allowing degradation over a period of up to about 18 or 24 months, eliminating the need for removal by a trained practitioner.

Abstract: A carrier system holds and facilitates access to implements usable with any one of a variety of tools. The carrier system includes a universal holder and a plurality of distinctive tool-attaching adapters. The universal holder defines implement-receiving openings, each of which is configured to receive a corresponding one of the implements therein. Each of the tools defines a distinctive carrier-receiving portion. Each of the tool-attaching adapters is engageable with and complementally corresponds to a respective one of the carrier-receiving portions. The universal holder is individually securable to the tool-attaching adapters. The universal holder is mountable to each the tools upon engagement of a selected one of the tool-attaching adapters with the respective one of the carrier-receiving portions, attachment of the selected one of the tool-attaching adapters to the respective one of the carrier-receiving portions, and securement of the universal holder to the selected one of the tool-attaching adapters.

Abstract: A support base for a child safety seat includes a pivotable support leg that is operable to retract and expand from the support base, the support leg including multiple segments connected with one another via a plurality of sliding connections, the sliding connections including a first and a second sliding connection. Moreover, the support base includes an actuating button operably coupled to a first and a second latch. The first latch is operable to lock and unlock the first sliding connection for preventing or allowing relative sliding between segments of the first sliding connection. The second latch is operable to lock and unlock the second sliding connection for preventing or allowing relative sliding between segments of the second sliding connection. When the actuating button is actuated, the first latch is urged to unlock the first sliding connection and the second latch is urged to unlock the second sliding connection.

Abstract: In some examples, an electronic device includes a network interface to connect to a computer network, a display port operating as a display input, an input/output port, memory having a plurality of profiles, and a processor coupled to the memory. In some examples, the processor is to change an operation of the input/output port based on a profile of the plurality of profiles. In some examples, the processor is to change the display port from the display input to a display output based on the profile of the plurality of profiles.

Abstract: A convertible child restraint includes a lower base to contact a vehicle seat, a seat shell to support a child, and a mid base between the lower base and the seat shell to facilitate recline and rotational adjustment of the seat shell relative to the lower base. The child restraint may be used as a rear-facing car seat, a forward-facing car seat, and a belt positioning booster seat. For the rear-facing car seat configuration, a belt is installed along a rear-facing belt path that passes through the child restraint. The portion of the belt in the child restraint is accessed via a belt access panel when the seat shell is at a rear-facing position. Additionally, the child restraint includes a rotation lockout that allows the seat shell to be rotated from a rear-facing position to a side-facing position, but not a forward-facing position when using the rear-facing configuration.

Abstract: A system and method are provided of minimizing network bandwidth used from an external network by client peers in a local network. The method can include the operation of organizing a plurality of clients each having media streamlets and a client parent in a structure within the local network. Mapping information propagates through the structure. The mapping information represents local streamlet locations as stored by the plurality of clients. Another operation is retrieving a local streamlet from a client identified in the mapping information as having the local streamlet for the requesting client.

Abstract: A diagnostic method, executable for example from remote computing devices or onboard control units for machines having various systems, each system having associated electronic controllers. For a specified machine and configuration, a hierarchical list is automatically generated comprising systems associated with the machine and one or more expected electronic controllers for each system. At least pursuant to initiation of a diagnostic program via an onboard control unit of the specified machine, respective input signals are obtained from present electronic controllers in functional communication with the onboard control unit.

Abstract: One example of an IP KVM device includes a USB port, a display port, a communication port, a network port, and a processor communicatively coupled to the USB port, display port, communication port, and network port. The USB port may be communicatively coupled to a host device to receive first USB signals from the host device. The display port may be communicatively coupled to the host device to receive first display signals from the host device. The communication port may be communicatively coupled to a secondary IP KVM device to receive second USB signals from the host device and second display signals from the host device. The network port may be communicatively coupled to a network. The processor is to aggregate the first and second USB signals and the first and second display signals and output the aggregated USB signals and display signals via the network port.

Abstract: An alert management system and technique is provided. Substantially any diagnostic trouble code generates an alert regardless of severity. The operator is given an option to dismiss or suppress re-alert for a class of diagnostic trouble codes, such as low severity codes. Future notification of such codes can be disabled in response to a selection of the option provided.

Abstract: A convertible child restraint includes a lower base to contact a vehicle seat, a seat shell to support a child, and a mid base between the lower base and the seat shell to facilitate recline and rotational adjustment of the seat shell relative to the lower base. The child restraint may be used as a rear-facing car seat, a forward-facing car seat, and a belt positioning booster seat. For the rear-facing car seat configuration, a belt is installed along a rear-facing belt path that passes through the child restraint. The portion of the belt in the child restraint is accessed via a belt access panel when the seat shell is at a rear-facing position. Additionally, the child restraint includes a rotation lockout that allows the seat shell to be rotated from a rear-facing position to a side-facing position, but not a forward-facing position when using the rear-facing configuration.

Abstract: Examples described herein relate to instructions to request performance of tanh and sigmoid instructions. For example, a compiler can generate native tanh instructions to perform tanh. In some examples, a tanh function can be compiled into instructions that include an instruction to perform either tanh(input) or tanh(input)/input depending on a value of the input to generate an intermediate output; an instruction to cause a performance of generation of scale factor based on the input; and an instruction to cause performance of a multiplication operation on the intermediate result with the scale factor. For example, a sigmoid function can be compiled to cause a math pipeline to perform a range check and performs operations based on a range.

Abstract: Embodiments are directed to systems and methods for reuse of FMA execution unit hardware logic to provide native support for execution of get exponent, get mantissa, and/or scale instructions within a GPU. These new instructions may be used to implement branch-free emulation algorithms for mathematical functions and analytic functions (e.g., transcendental functions) by detecting and handling various special case inputs within a pre-processing stage of the FMA execution unit, which allows the main dataflow of the FMA execution unit to be bypassed for such special cases. Since special cases are handled by the FMA execution unit, library functions emulating various functions, including, but not limited to logarithm, exponential, and division operations may be implemented with significantly fewer lines of machine-level code, thereby providing improved performance for HPC applications.

Abstract: A host device has a hardware-based remote control mode and a softwarebased remote control mode. The availability of each of the hardware- and software-based remote control modes is monitored. Client device remote control of the host device is selectively switched between the hardware- and softwarebased remote control modes, based on the monitored availability of each remote control mode.

Abstract: A rearview assembly includes an electrochromic element. The electrochromic element includes a first substrate including a first surface and a second surface. The electrochromic element further includes a second substrate comprising a third surface and a fourth surface. The first substrate and the second substrate form a cavity. The electrochromic element includes an electrochromic medium contained in the cavity. The rearview assembly includes an image sensor directed toward the fourth surface and configured to capture near-infrared light reflected from an object and projected through the electrochromic element. The rearview assembly includes a transflective film disposed adjacent to the fourth surface having a near-infrared light transmission level and a visible light reflectance level.

Abstract: A child restraint base adapted to a child restraint carrier is disclosed herein. The child restraint base includes a base body including a first pocket and a second pocket. The first pocket and the second pocket are disposed on front lateral sides of the base body. An anchor belt is included that comprises a first anchor attached to a first end of the anchor belt, and a second anchor attached to a second end of the anchor belt. The first pocket is configured to receive at least a portion of the first anchor, and the second pocket is configured to receive at least a portion of the second anchor. A panel is pivotable between an opened position and a closed position, and the panel pivots to the closed position to tension the anchor belt to remove slack from the anchor belt.

Abstract: The present invention provides compounds and methods for treating MKP-5 modulated disease. In certain embodiments, the MKP-5 modulated disease is a fibrotic disease.

Abstract: An electro-optic assembly includes a first substrate that has a first surface and a second surface opposite the first surface. A second substrate has a third surface and a fourth surface opposite the third surface. The second and third surfaces face each other to define a gap. A first electrode stack is coupled to the second surface, and a second electrode stack is coupled to the third surface. An electro-optic medium is located between the first electrode stack and the second electrode stack. At least one of the first and second electrode stacks includes a base layer, a conduction layer formed of a transparent conductive material, and a flexible conductive layer spaced from the base layer by the conduction layer. The flexible conductive layer is formed of an electrically conductive polymer.

Abstract: An electrochromic device, system using, and method for, which may pre-activate a buffer is disclosed. The electrochromic device may comprise a first substrate, a second substrate, a first electrode, a second electrode, and an electrochromic medium. The second substrate may be disposed in apart relationship with the first substrate. The first and second electrodes may be associated with the first and second substrates, respectively. The electrochromic medium may be disposed between the first and second electrodes. Further, the electrochromic medium may comprise electrochromic materials and a redox buffer. Each of the electrochromic materials and the buffer may be operable between activated and deactivated states. The electrochromic device may be configured to apply a voltage to substantially pre-activate the buffer and hold the buffer in this state prior to substantially activating the electrochromic materials, thereby decreasing the response time of the electrochromic device upon activation.

Abstract: A reflective member having transflective and substantially opaque regions is disclosed. The transflective region may serve as a sensor opening region. When viewing the member from a first direction, the difference between a total light reflectance of the member at the substantially opaque region and at the sensor opening region is less than five percent. Additionally, when viewing the member from the first direction, the difference between a color reflectance of the member at the substantially opaque region and at the sensor opening region is less than 5 delta C* units. A sensor disposed in a second direction of the sensor opening region of the member is operable to receive light through the member at the sensor opening region. The second direction is opposite the first direction.