Abstract: The avionic system of an aircraft includes a set of avionic computers and a switch associated with each avionic computer. For each avionic computer of the set of avionic computers, the avionic system includes a communication link between the switch associated with this avionic computer and each of the switches associated with the other avionic computers. Each switch is configured such that it routes the data frames received on its input ports to its output ports in a manner predefined only on the basis of the input ports on which these data frames are received. The various switches are configured such that, when an avionic computer sends a data frame, this data frame is transmitted to all of the other avionic computers.

Abstract: The present disclosure provides a method for genetic analysis for disease diagnoses, as well as a system for implementing such analysis. Provided is a comprehensive, scalable, biotechnology solution that solves diagnostic and therapeutic complications in rapidly progressive childhood genetic diseases. As such, the invention provides Genome-to-Treatment (GTRx?), which is an automated, virtual system for genetic disease diagnosis and acute management guidance.

Abstract: The avionic system of an aircraft includes a set of avionic computers and a switch associated with each avionic computer. For each avionic computer of the set of avionic computers, the avionic system includes a communication link between the switch associated with this avionic computer and each of the switches associated with the other avionic computers. Each switch is configured such that it routes the data frames received on its input ports to its output ports in a manner predefined only on the basis of the input ports on which these data frames are received. The various switches are configured such that, when an avionic computer sends a data frame, this data frame is transmitted to all of the other avionic computers.

Abstract: A chromatography column design and a packing device, as well as a method for obtaining a column with a very compact and uniform bed are provided. The bed remains compact and uniform during operation of the column and during sanitization, storage and transportation of the column. The amount of hardware, particularly the hardware parts in contact with product, is minimized, especially with the implementation of an internal liner. With this internal liner, the packed bed can be separated from the column in intact form, or even prepared separately from, and outside of, the column.

Abstract: A chromatography column design and a packing device, as well as a method for obtaining a column with a very compact and uniform bed are provided. The bed remains compact and uniform during operation of the column and during sanitization, storage and transportation of the column. The amount of hardware, particularly the hardware parts in contact with product, is minimized, especially with the implementation of an internal liner. With this internal liner, the packed bed can be separated from the column in intact form, or even prepared separately from, and outside of, the column.

Abstract: A preparative chromatography column is equipped with one or more valves that can each be used to both inject a column packing into the column or withdraw used packing from the column, in addition to cleaning the supply and discharge lines associated with the valve itself, all by moving a movable plug within the valve body and all without protruding into the column interior. Each valve is mounted on the lateral wall of the column just above the filter plate at the column floor, and the plug is movable between a closed position in which the end surface of the plug is flush with the inner wall of the column and an open position in which the plug is recessed within the bore. Each valve has two additional ports in its valve body, positioned such that when the plug is closed, both ports are open to the valve bore, and when the plug is open, at least one of the ports is open to the bore. The position of the plug within the valve bore determines the valve function.

Abstract: System and method for calibrating a time constant R0Ci of an integrated electronic current-feedback continuous-time delta sigma analog/digital converter (modulator) having a variable-impedance filter coupled to input of the modulator, an analog input signal Vin of fixed frequency applied to the variable-impedance filter, wherein the analog input signal Vin attenuation engendered by the variable-impedance filter is measured, and the value of a time constant R0Ci in the modulator and value of the impedance of the variable-impedance filter are modified until an attenuation corresponding to the desired attenuation for the integrated electronic circuit modulator is obtained.

Abstract: The plunger used as the upper enclosure in a preparative chromatography column is suspended by one or more rods that are supported by a frame through coupling connections on the frame that can fix the position of the rod(s) relative to the frame, while the position of the rod(s) is controlled by a motorized drive system that is suspended above the column. The drive system is mounted either to the column lid or to a functional plate positioned a short distance above the column lid. These constructions allow the plunger to be raised and lowered so that the column and its parts can be exchanged, all without the need for a hoist or crane.

Abstract: A chromatography column design and a packing device, as well as a method for obtaining a column with a very compact and uniform bed are provided. The bed remains compact and uniform during operation of the column and during sanitization, storage and transportation of the column. The amount of hardware, particularly the hardware parts in contact with product, is minimized, especially with the implementation of an internal liner. With this internal liner, the packed bed can be separated from the column in intact form, or even prepared separately from, and outside of, the column.

Abstract: System and method for calibrating a time constant R0Ci of an integrated electronic current-feedback continuous-time delta sigma analog/digital converter (modulator) having a variable-impedance filter coupled to the input of the modulator, an analog input signal Vin of fixed frequency applied to the variable-impedance filter, wherein the analog input signal Vin attenuation engendered by the variable-impedance filter is measured, and the value of a time constant R0Ci in the modulator and the value of the impedance of the variable-impedance filter are modified until an attenuation corresponding to the desired attenuation for the integrated electronic circuit modulator is obtained.

Abstract: A preparative chromatography column is equipped with one or more valves that can each be used to both inject a column packing into the column or withdraw used packing from the column, in addition to cleaning the supply and discharge lines associated with the valve itself, all by moving a movable plug within the valve body and all without protruding into the column interior. Each valve is mounted on the lateral wall of the column just above the filter plate at the column floor, and the plug is movable between a closed position in which the end surface of the plug is flush with the inner wall of the column and an open position in which the plug is recessed within the bore. Each valve has two additional ports in its valve body, positioned such that when the plug is closed, both ports are open to the valve bore, and when the plug is open, at least one of the ports is open to the bore. The position of the plug within the valve bore determines the valve function.

Abstract: The plunger used as the upper enclosure in a preparative chromatography column is suspended by one or more rods that are supported by a frame through coupling connections on the frame that can fix the position of the rod(s) relative to the frame, while the position of the rod(s) is controlled by a motorized drive system that is suspended above the column. The drive system is mounted either to the column lid or to a functional plate positioned a short distance above the column lid. These constructions allow the plunger to be raised and lowered so that the column and its parts can be exchanged, all without the need for a hoist or crane.

Abstract: The plunger used as the upper enclosure in a preparative chromatography column is suspended by one or more rods that are supported by a frame through coupling connections on the frame that can fix the position of the rod(s) relative to the frame, while the position of the rod(s) is controlled by a motorized drive system that is suspended above the column. The drive system is mounted either to the column lid or to a functional plate positioned a short distance above the column lid. These constructions allow the plunger to be raised and lowered so that the column and its parts can be exchanged, all without the need for a hoist or crane.

Abstract: A preparative chromatography column is equipped with one or more valves that can each be used to both inject a column packing into the column or withdraw used packing from the column, in addition to cleaning the supply and discharge lines associated with the valve itself, all by moving a movable plug within the valve body and all without protruding into the column interior. Each valve is mounted on the lateral wall of the column just above the filter plate at the column floor, and the plug is movable between a closed position in which the end surface of the plug is flush with the inner wall of the column and an open position in which the plug is recessed within the bore. Each valve has two additional ports in its valve body, positioned such that when the plug is closed, both ports are open to the valve bore, and when the plug is open, at least one of the ports is open to the bore. The position of the plug within the valve bore determines the valve function.

Abstract: An embodiment of a device for memorization of a memory bit is provided, comprising a bistable circuit having complementary first and second read/write terminals, wherein the device comprises an initialization input connected to said bistable circuit, said input being designed to go into a first state controlling a pre-load phase of said bistable circuit and following said preload phase, to go into a second state controlling setting up of said memory bit and its complement at said read/write terminals.

Abstract: The plunger used as the upper enclosure in a preparative chromatography column is suspended by one or more rods that are supported by a frame through coupling connections on the frame that can fix the position of the rod(s) relative to the frame, while the position of the rod(s) is controlled by a motorized drive system that is suspended above the column. The drive system is mounted either to the column lid or to a functional plate positioned a short distance above the column lid. These constructions allow the plunger to be raised and lowered so that the column and its parts can be exchanged, all without the need for a hoist or crane.

Abstract: A non-volatile memory element includes a transistor for selecting the element and a capacitor for recording a binary value by electrical breakdown of an insulating layer of the capacitor. A structure of the memory element is modified in order to allow a higher degree of integration of the element within an electronic circuit of the MOS type. In addition, the memory element is made more robust with respect to a high electrical voltage (VDD) used for recording the binary value. The transistor includes a drain in the substrate with electric field drift in a longitudinal direction extending towards the capacitor. The electric field drift region for the drain includes a first extension underneath the gate of the transistor opposite the source and a second extension underneath the insulating layer of the capacitor. Doping of the substrate for the electric field drift region is limited to a region substantially corresponding to a distance between the gate and an electrode of the capacitor.

Abstract: A non-volatile memory element includes a transistor for selecting the element and a capacitor for recording a binary value by electrical breakdown of an insulating layer (13) of the capacitor. A structure of the memory element is modified in order to allow a higher degree of integration of the element within an electronic circuit of the MOS type. In addition, the memory element is made more robust with respect to a high electrical voltage (VDD) used for recording the binary value. The transistor includes a drain in the substrate with electric field drift in a longitudinal direction extending towards the capacitor. The electric field drift region for the drain includes a first extension underneath the gate of the transistor opposite the source and a second extension underneath the insulating layer of the capacitor. Doping of the substrate for the electric field drift region is limited to a region substantially corresponding to a distance between the gate and an electrode of the capacitor.

Abstract: The plunger used as the upper enclosure in a preparative chromatography column is suspended by one or more rods that are supported by a frame through coupling connections on the frame that can fix the position of the rod(s) relative to the frame, while the position of the rod(s) is controlled by a motorized drive system that is suspended above the column. The drive system is mounted either to the column lid or to a functional plate positioned a short distance above the column lid. These constructions allow the plunger to be raised and lowered so that the column and its parts can be exchanged, all without the need for a hoist or crane.

Abstract: A preparative chromatography column is equipped with one or more valves that can each be used to both inject a column packing into the column or withdraw used packing from the column, in addition to cleaning the supply and discharge lines associated with the valve itself, all by moving a movable plug within the valve body and all without protruding into the column interior. Each valve is mounted on the lateral wall of the column just above the filter plate at the column floor, and the plug is movable between a closed position in which the end surface of the plug is flush with the inner wall of the column and an open position in which the plug is recessed within the bore. Each valve has two additional ports in its valve body, positioned such that when the plug is closed, both ports are open to the valve bore, and when the plug is open, at least one of the ports is open to the bore. The position of the plug within the valve bore determines the valve function.