Patents by Inventor S. Betty Yan

S. Betty Yan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vectors and compounds for expression of zymogen forms of human protein C
    Patent number: 5196322
    Abstract: A method for the recombinant production of zymogen forms of human protein C is described. These zymogen forms differ from native zymogen protein C in their increased sensitivity to activation by thrombin and thrombin/thrombomodulin. DNA compounds, vectors, and transformants useful in the method are also disclosed.
    Type: Grant
    Filed: October 4, 1991
    Date of Patent: March 23, 1993
    Assignee: Eli Lilly and Company
    Inventors: Nils U. Bang, Hartmut Ehrlich, Brian W. Grinnell, S. Betty Yan
  • Method for the purification of vitamin K-dependent proteins
    Patent number: 4981952
    Abstract: The recovery of vitamin K-dependent proteins produced by transformed microorganisms can be effected from the cell culture medium utilizing the changes in the protein which occur in the presence of divalent cations. The present process uses divalent cations to alter the binding affinity of the proteins and thereby selectively elute the proteins away from contaminants in the culture medium using standard chromatography.
    Type: Grant
    Filed: August 16, 1989
    Date of Patent: January 1, 1991
    Assignee: Eli Lilly and Company
    Inventor: S. Betty Yan