Patents by Inventor S. David Gertz

S. David Gertz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PDGF receptor kinase inhibitory compounds, their preparation, purification and pharmaceutical compositions including same
    Patent number: 6358954
    Abstract: An isometric enriched tyrphostin of a general formula: wherein, for Compound I, the tyrphostin is enriched either for R6 at position 6 or for R6 at position 7, or, for Compound II, the tyrphostin is enriched either for R6 at position 6 or for R6 at position 8. Further disclosed are pharmaceutical compositons containing the isometric enriched tyrphostin and methods of using same to treat cell proliferative diseases.
    Type: Grant
    Filed: November 9, 1999
    Date of Patent: March 19, 2002
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Alexander Levitzki, Aviv Gazit, Shmuel Banai, S. David Gertz, Gershon Golomb, Frank D. Boehmer, Johannes Waltenberger
  • PDGF receptor kinase inhibitory compounds their preparation and compositions
    Patent number: 5932580
    Abstract: PDGF receptor kinase inhibitory compounds of the quinoxaline family, methods for their synthesis and containment is slow release pharmaceutical preparations, and their use for treatment of proliferative malignant and non-malignant diseases or disorders by local or systemic application. A compound according to the invention includes a tyrphostin of the general formula: ##STR1## wherein R1 and R2 are each independently selected from the group consisting of alkyl, alkoxy, halogen, nitro and amine and Ar is selected from the group consisting of phenyl, ferrocene, thiophene, furane, pyrrole, indole, thiazole, imidazole and pyridine.
    Type: Grant
    Filed: December 1, 1997
    Date of Patent: August 3, 1999
    Assignee: Yissum Research and Development Company of the Hebrew University of Jerusalem
    Inventors: Alexander Levitzki, Aviv Gazit, Shmuel Banai, S. David Gertz, Gershon Golomb