Patents by Inventor S. Esmail Tabibi

S. Esmail Tabibi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Water-insoluble drug delivery system
    Patent number: 6838090
    Abstract: The present invention provides a drug delivery system comprising a water-insoluble drug, a water-miscible organic solvent for the water-insoluble drug, a surfactant, and water, as well as a process for preparing the same. This invention further provides a pharmaceutical composition comprising a pharmaceutically acceptable carrier and such a drug delivery system. In addition, the present invention provides a method of delivering a drug to a host by administering to the host the drug delivery system of the present invention.
    Type: Grant
    Filed: June 5, 2003
    Date of Patent: January 4, 2005
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: S. Esmail Tabibi, Emmanuel I. Ezennia, B. Rao Vishnuvajjala, Shanker Gupta
  • Water-insoluble drug delivery system
    Patent number: 6682758
    Abstract: The present invention provides a drug delivery system comprising a water-insoluble drug, a water-miscible organic solvent for the water-insoluble drug, a surfactant, and water, as well as a process for preparing the same. This invention further provides a pharmaceutical composition comprising a pharmaceutically acceptable carrier and such a drug delivery system. In addition, the present invention provides a method of delivering a drug to a host by administering to the host the drug delivery system of the present invention.
    Type: Grant
    Filed: June 21, 2001
    Date of Patent: January 27, 2004
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: S. Esmail Tabibi, Emmanuel I. Ezennia, B. Rao Vishnuvajjala, Shanker Gupta
  • Water-insoluble drug delivery system
    Publication number: 20030211144
    Abstract: The present invention provides a drug delivery system comprising a water-insoluble drug, a water-miscible organic solvent for the water-insoluble drug, a surfactant, and water, as well as a process for preparing the same. This invention further provides a pharmaceutical composition comprising a pharmaceutically acceptable carrier and such a drug delivery system. In addition, the present invention provides a method of delivering a drug to a host by administering to the host the drug delivery system of the present invention.
    Type: Application
    Filed: June 5, 2003
    Publication date: November 13, 2003
    Applicant: Government of the U.S.A., represented by the Secretary, Department of Health and Human Services
    Inventors: S. Esmail Tabibi, Emmanuel I. Ezennia, B. Rao Vishnuvajjala, Shanker Gupta
  • Controlled release aqueous emulsion
    Patent number: 5672358
    Abstract: A controlled release aqueous emulsion is disclosed, as are its method of manufacture and use as a vehicle for delivering medicaments in liquid form. A contemplated emulsion comprises an oil-in-water emulsion having an average oil particle size of about 100 nm to about 250 nm, a pH value of about 4.5 to about 8.0 and a viscosity at 20.degree.-25.degree. C. of 1 to about 1000 cps. The water phase constitutes at least 25 weight percent of the total composition. The oil phase is a wax matrix that is a wax having a melting point of about 40.degree. to about 80.degree. C. and is present in an amount of about 3 to about 30 percent of the total composition. A pharmaceutically effective amount of a pharmacologically active compound that is free from decomposition at a temperature below about 90.degree. C. is dissolved or dispersed in the wax matrix. The oil and water phases are emulsified by an emulsifying agent that provides freedom from phase separation at a pH value of about 4.
    Type: Grant
    Filed: June 19, 1995
    Date of Patent: September 30, 1997
    Assignee: Ascent Pharmaceuticals, Inc.
    Inventors: S. Esmail Tabibi, Robert W. Mendes, Nitin P. Pathak
  • Lipid vesicles having an alkyd as a wall-forming material
    Patent number: 5164191
    Abstract: The present invention features a method of making lipid vesicles and the lipid vesicles themselves made from monomeric and dimeric alkyds. These alkyds are esters made as a condensation product of a first reactant having at least one free hydroxyl group and a C.sub.12 -C.sub.20 fatty acids chain and a second reactant which is an aromatic acid chloride or anhydride. Preferred first reactants are esters of polyols and C.sub.12 -C.sub.20 fatty acids, ethers of polyols and C.sub.12 -C.sub.20 fatty acids, and C.sub.12 -C.sub.20 fatty alcohols.
    Type: Grant
    Filed: February 12, 1991
    Date of Patent: November 17, 1992
    Assignee: Micro Vesicular Systems, Inc.
    Inventors: S. Esmail Tabibi, An-Cheng Chang, Rajiv Mathur, Donald F. H. Wallach