Patents by Inventor S. Gnanakaran

S. Gnanakaran has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mosaic HIV envelope immunogenic polypeptides
    Patent number: 9855329
    Abstract: Disclosed herein are mosaic HIV envelope (Env) polypeptides that can elicit an immune response to HIV (such as cytotoxic T cell (CTL), helper T cell, and/or humoral responses). Also disclosed are sets of the disclosed mosaic Env polypeptides, which include two or more (for example, three) of the polypeptides. Also disclosed herein are methods for treating or inhibiting HIV in a subject including administering one or more of the disclosed immunogenic polypeptides or compositions to a subject infected with HIV or at risk of HIV infection. In some embodiments, the methods include inducing an immune response to HIV in a subject comprising administering to the subject at least one (such as two, three, or more) of the immunogenic polypeptides or at least one (such as two, three, or more) nucleic acids encoding at least one of the immunogenic polypeptides disclosed herein.
    Type: Grant
    Filed: September 30, 2014
    Date of Patent: January 2, 2018
    Assignees: Los Alamos National Security, LLC, Dana-Farber Cancer Institute, Duke University
    Inventors: Bette T. M. Korber, S. Gnanakaran, Simon Perkins, Joseph Sodroski, Barton Haynes
  • MOSAIC HIV ENVELOPE IMMUNOGENIC POLYPEPTIDES
    Publication number: 20160235836
    Abstract: Disclosed herein are mosaic HIV envelope (Env) polypeptides that can elicit an immune response to HIV (such as cytotoxic T cell (CTL), helper T cell, and/or humoral responses). Also disclosed are sets of the disclosed mosaic Env polypeptides, which include two or more (for example, three) of the polypeptides. Also disclosed herein are methods for treating or inhibiting HIV in a subject including administering one or more of the disclosed immunogenic polypeptides or compositions to a subject infected with HIV or at risk of HIV infection. In some embodiments, the methods include inducing an immune response to HIV in a subject comprising administering to the subject at least one (such as two, three, or more) of the immunogenic polypeptides or at least one (such as two, three, or more) nucleic acids encoding at least one of the immunogenic polypeptides disclosed herein.
    Type: Application
    Filed: September 30, 2014
    Publication date: August 18, 2016
    Applicants: Los Alamos National Security, LC/TAS, Duke University, Dana-Farber Cancer Institute
    Inventors: Bette T.M. Korber, S. Gnanakaran, Simon Perkins, Joseph Sodroski, Barton Haynes