Abstract: The present disclosure provides methods for preparing MCL1 inhibitors or a salt thereof and related key intermediates.

Abstract: A diatomite product and method of using such is disclosed. The diatomite product may comprise sodium flux-calcined diatomite, wherein the diatomite product has a crystalline silica content of less than about 1 wt %, and the diatomite product has a permeability between 0.8 darcy and about 30 darcy. In some embodiments, the diatomite product may be in particulate or powdered form. This disclosure also concerns flux-calcined silica products containing low or non-detectable levels of crystalline silica. Some of these products can be further characterized by high permeabilities and a measurable content of opal-C, a hydrated form of silicon dioxide.

Abstract: A method of determining opal-C and cristobalite contents of a product that comprises diatomite is disclosed. The method may comprise performing thermal processing to determine a loss on ignition for a representative first portion of a sample of the product; identifying and quantifying primary and secondary peaks present in a first diffraction pattern that results from bulk powder X-ray Diffraction on a representative second portion of the sample; and using a known standard sample of cristobalite to determine whether the primary and secondary peaks present in the first diffraction pattern indicate the presence of opal-C or cristobalite in the product.

Abstract: A method of determining opal-C and cristobalite contents of a product that comprises diatomite is disclosed. The method may comprise performing thermal processing to determine a loss on ignition for a representative first portion of a sample of the product; identifying and quantifying primary and secondary peaks present in a first diffraction pattern that results from bulk powder X-ray Diffraction on a representative second portion of the sample; and using a known standard sample of cristobalite to determine whether the primary and secondary peaks present in the first diffraction pattern indicate the presence of opal-C or cristobalite in the product.

Abstract: Products (4) comprising a physical component (6) and Silica Documentation (8), and methods of preparing such products (4) are disclosed. In some embodiments, the physical component (6) may be powdered or in particulate form. The physical component (6) includes diatomite. In such products (4), a crystalline silica content of the physical component (6) by weight is greater as measured according to Traditional Methods than as measured according to a method that differentiates between opal-C and cristobalite. The Silica Documentation (8) discloses the crystalline silica content present in the physical component (6) as measured according to the method that differentiates between opal-C and cristobalite. The method of preparing the product (4) may include analyzing the physical component (6) for crystalline silica content using an LH Method to determine cristobalite content and preparing Silica Documentation (8) based on the results of the LH Method.

Abstract: A diatomite product and method of using such is disclosed. The diatomite product may comprise sodium flux-calcined diatomite, wherein the diatomite product has a crystalline silica content of less than about 1 wt %, and the diatomite product has a permeability between 0.8 darcy and about 30 darcy. In some embodiments, the diatomite product may be in particulate or powdered form. This disclosure also concerns flux-calcined silica products containing low or non-detectable levels of crystalline silica. Some of these products can be further characterized by high permeabilities and a measurable content of opal-C, a hydrated form of silicon dioxide.

Abstract: A modular sterilizable surgical table that obviates the need for sterile drapes is particularly adapted for use during surgery in hospital operating rooms or in a veterinary health care facility. The table may include a movable base to which a plurality of posts is fixedly attached. A plurality of sterilizable sleeves may be detachably coupled to the plurality of posts. A first sterilizable shelf structured to hold sterilized medical instruments and/or supplies during a medical procedure is detachably coupled to at least one of the sleeves. A second sterilizable shelf structured to hold sterilized medical instruments and/or supplies is detachably coupled to at least another one of the sleeves. Each of the sleeves and shelves is each removable from the table sterilization. The shelves may be adjustable and include one or more lips to retain items placed on the shelves.

Abstract: Magnetic stainless steel needles are detectable in processed meat. The previous non magnetic versions, made of 304 stainless steel, aren't. Disposable hypodermic needles made from martensitic and ferritic stainless steel are easily detectable at the smallest size. Needles are conveniently made from 420 martensitic stainless steel or 430 ferritic stainless steel.

Abstract: A method and apparatus for increasing peer-to-peer bandwidth between remote networks by combining multiple connections, which use arbitrary data paths, is disclosed. The apparatus is a gateway node, which can be a specifically designed computer, open computer platform or extensions to firmware resident in a router; gateway or remote access server. The method includes origin authentication and data confidentiality, packet fragmenting, sequencing directed-routing, buffering, fragment encapsulation, packet re-assembly, and additional encapsulation for traversal of firewalls. Packet fragments transferred using the method can travel along very diverse paths through intervening public or private networks before arriving at the peer, which reassembles them. This eliminates the problems present in current aggregation schemes used by prior art, which are sensitive to the limitations in the infrastructure in the service provider's points of presence.

Abstract: A portable sports shed is adaptable for resting on the ground or for residing within the bed of a pick-up truck. The shed has a lower section which is sized to fit within the truck bed, and a wider upper section that has side walls and a transversely arcuate roof. Laterally extending bench sections interconnect the lower and upper sections. Each end wall of the shed has a pair of doors providing access to the shed and the floor has at least three parallel grooves therein which define skids on the exterior bottom. The grooves will accept the skids of a snowmobile or the wheels of an ATV, a lawn and garden tractor or one or more bicycles or motorcycles. When the shed is mounted in the truck it can protect a vehicle housed therein from the elements or it can be used as a camper. When resting on the ground it acts as a garage, permitting a vehicle to be driven in via one set of doors and out via the other set of doors.

Abstract: A water soluble, thermally stable, solder flux for use in forming a water soluble, thermally stable, solder paste is provided. The water soluble, thermally stable, solder flux contains an acidic ester component having about 50% to about 60% monoesters by weight based on total weight, about 40% to about 50% diesters by weight based on total weight, and about 0% to about 1.5% phosphoric acid by weight based on total weight. This ester component is combined with triethanolamine to form a flux vehicle having a molar ratio of triethanolamine to the ester component of about 0.6 to about 1.2. This vehicle is present in the solder flux in an amount from about 68% to about 79% by weight based on total weight of solder flux. The flux also contains rheology adjusting components in an amount ranging from about 17% to about 26% by weight based on total weight of solder flux. Citric acid included in the flux in an amount ranging from about 4% to about 6% by weight based on total weight of solder flux.

Abstract: An automatic volume control system comprises a source for producing an audio signal; an amplifier responsive to a control signal for varying the amplitude of the audio signal, a transducer for converting the audio signal to sound energy, a detector for detecting the output of the transducer and ambient noise which interferes with comprehension of the sound energy, and a phase comparator connected to the detector and to the audio signal source for comparing the phases of the outputs thereof and for producing an output proportional to the level of detected ambient noise. The output of the phase comparator is connected as a control signal to the amplifier means so as to control the amplitude of the audio signal.

Abstract: A coated polycarbonate article comprising a polycarbonate substrate having (i) a primer layer comprising a UV cured reaction product of a polyfunctional acrylic ester monomer and an organic silicon compound of the formula R.sup.3.sub.c SiX.sub.(4-c) wherein R.sup.3 is an organic moiety containing olefinic unsaturation, X is an alkoxy, acyloxy and aryloxy group, and c is an integer of from 1 to 3; and (ii) a thermoset organopolysiloxane coating on said UV cured primer layer.A process for producing a coated polycarbonate article comprising (i) priming a polycarbonate substrate with a UV curable primer composition containing (a) a polyfunctional acrylic ester monomer, (b) an organic silicon compound of the formula R.sup.3.sub.c SiX.sub.(4-c), wherein R, X and c are as defined above; and (c) a UV photo initiator; (ii) UV curing said primer composition; (iii) applying an organopolysiloxane coating composition to the primed substrate; and (iv) curing the organopolysiloxane.

Abstract: A coated polycarbonate article comprising a polycarbonate substrate having (i) a primer layer containing a UV cured reaction product of (a) a polyfunctional acrylic ester monomer, (b) an organic silicon compound represented by the formula R.sup.4.sub.c SiX.sub.4-c wherein R.sup.4 is an organic group containing olefinic unsaturation, X is an alkoxy, acyloxy, and aryloxy group, and c is an integer of from 1 to 3, and (c) an acrylate modified polymer; and (ii) a thermoset organopolysiloxane coating on said UV cured primer layer.A process for producing a coated polycarbonate article comprising (i) priming a polycarbonate substrate with a UV curable primer composition containing (a) a polyfunctional acrylic acid ester monomer, (b) an organic silicon compound represented by the formula R.sup.4.sub.c SiX.sub.4-c, wherein R.sup.

Abstract: A coated polycarbonate article comprising a polycarbonate substrate having (i) a primer layer containing a UV cured reaction product of (a) a polyfunctional acrylic ester monomer, (b) an organic silicon compound represented by the formula R.sup.4.sub.c SiX.sub.4-c wherein R is an organic group containing olefinic unsaturation, X is an alkoxy, acyloxy, and aryloxy group, and c is an integer of from 1 to 3, and (c) an acrylate modified polymer; and (ii) a thermoset silica filled organopolysiloxane top coat on said UV cured primer layer.A process for producing a coated polycarbonate article comprising (i) priming a polycarbonate substrate with a UV curable primer composition containing (a) a polyfunctional acrylic acid ester monomer, (b) an organic silicon compound represented by the formula R.sup.4.sub.c SiX.sub.

Abstract: An abrasion, scratch, mar and solvent resistant glass coated non-opaque shaped polycarbonate article comprising a polycarbonate substrate having deposited on the surface thereof (i) an intermediate primer layer containing the photoreaction products of certain polyfunctional acrylic monomers; and (ii) a top layer of vapor deposited glass.

Abstract: Magnetic stainless steel needles are detectable in processed meat. The previous non magnetic versions, made of 304 stainless steel, aren't. Disposable hypodermic needles made from martensitic and ferritic stainless steel are easily detectable at the smallest size. Needles are conveniently made from 420 martensitic stainless steel or 430 ferritic stainless steel.