Patents by Inventor S. Mbua Ngale Efange

S. Mbua Ngale Efange has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nicotine receptor ligands
    Patent number: 6846817
    Abstract: The invention provides nicotine receptor agonists of formula I: wherein R1, x, y, and n have any of the values given in the specification, or a pharmaceutically acceptable salt thereof, as well as pharmaceutical compositions comprising such a compound or salt, methods for preparing such a compound or salt, and methods for modulating (e.g. antagonizing or activating) nicotine receptors with such a compound or salt.
    Type: Grant
    Filed: November 30, 2001
    Date of Patent: January 25, 2005
    Assignee: Regents of the University of Minnesota
    Inventor: S. Mbua Ngale Efange
  • Nicotine receptor ligands
    Publication number: 20030027810
    Abstract: The invention provides nicotine receptor agonists of formula I: 1
    Type: Application
    Filed: November 30, 2001
    Publication date: February 6, 2003
    Applicant: Regents of the University of Minnesota
    Inventor: S. Mbua Ngale Efange
  • Spiroindanamines and Spiroindanimides
    Patent number: 5948807
    Abstract: Compounds of formula I: ##STR1## wherein R.sup.1, R.sup.2, W, X, Y and Z have any of the values defined in the specification, and their pharmaceutically acceptable salts, are inhibitors of monoamine re-uptake and are useful for treating diseases in mammals wherein insufficient synaptic levels of monoamine are implicated. Also disclosed are pharmaceutical compositions, processes for preparing compounds of formula I, and intermediates useful for the synthesis of compounds of formula I.
    Type: Grant
    Filed: September 3, 1997
    Date of Patent: September 7, 1999
    Assignee: Regents of the University of Minnesota
    Inventors: S. Mbua Ngale Efange, Deborah Carmen Mash
  • Decahydroquinoline-based anti-cholinergic agents
    Patent number: 5929087
    Abstract: Compounds of formula I or formula II: ##STR1## wherein R, J, and Q have any of the values defined in the specification, and their pharmaceutically acceptable salts and related radiopharmaceuticals, have anticholinergic activity, and are useful for modulating cholinergic function in mammals. Also disclosed are pharmaceutical compositions, processes for preparing compounds of formula (I) or (II) and intermediates.
    Type: Grant
    Filed: April 8, 1997
    Date of Patent: July 27, 1999
    Assignee: Regents of the University of Minnesota
    Inventors: S. Mbua Ngale Efange, Stanley M. Parsons