Abstract: Systems and methods for identifying a likelihood that a reservoir of a geological formation received a secondary charge of hydrocarbons of relatively very different thermal maturity of composition are provided. One method includes positioning a downhole acquisition tool in a wellbore in a geological formation and testing one or more fluid properties of the formation fluid. Data processing circuitry may identify whether a relationship of the one or more fluid properties exceeds a first threshold that indicates likely asphaltene instability. When this is the case, data processing circuitry may be used to model the geological formation using a realization scenario in which multiple charges of hydrocarbons of substantially different thermal maturity or substantially different composition, or both, filled a reservoir of the geological formation over geologic time.

Abstract: The present technology provides compounds according to Formula I or Formula III as well as compositions including such compounds useful for the treatment of metastatic cancer and/or glaucoma.

Abstract: Provided herein are methods of tipifarnib in combination with a PI3K inhibitor, such as alpelisib, for treating, preventing or managing head and neck squamous cell carcinoma (HNSCC).

Abstract: In some implementations, a first network device may encode Internet protocol version 4 (IPv4) next hop of Internet protocol version 6 (IPv6) information. The first network device may advertise the IPv6 information to a second network device via an IPv4 border gateway protocol. The first network device may forward an IPv6 packet via an IPv4 interface associated with the first network device based on advertising the IPv6 information.

Abstract: Devices and techniques are generally described for generating customized invoice data. In some examples, first data describing invoice settings for a first entity may be received during a registration process. In various examples, a plurality of invoice customizations may be determined based on a similarity between the first data and historical invoice settings of other entities. In some examples, the customized invoice data comprising the plurality of invoice customizations may be generated. In at least some examples, the customized invoice data may be stored in non-transitory computer-readable memory.

Abstract: In some implementations, a first network device may encode Internet Protocol version 4 (IPv4) network layer reachability information (NLRI) using Internet Protocol version 6 (IPv6) next hop encoding to generate encoded IPv4 NLRI. The first network device may include information indicating border gateway protocol (BGP) labeled unicast (BGP-LU) in the encoded IPv4 NLRI. The first network device may advertise the encoded IPv4 NLRI. The first network device may establish a communication session with a second network device, wherein the communication session is established via an IPv6 core network. The first network device may forward, via the communication session, one or more IPv4 packets using the encoded IPv4 NLRI.

Abstract: A first network device associated with a network may establish an Internet protocol version 6 Multiprotocol BGP session with a second network device associated with the network. The first network device and second network device are both capable of forwarding both IPv4 and IPv6 packets with only an IPv6 address configured on the interface of both the first network device and second network device. The first network device may exchange Multiprotocol Reachability capability with second network device for corresponding 2-tuple Address Family Identifier/Subsequent Address Family Identifier. The first network device may advertise Internet protocol version 4 network layer reachability information and may advertise Internet protocol version 6 network layer reachability information with IPv6 extended next hop encoding using Internet Assigned Numbering Authority assigned capability code value 5 to second network device.

Abstract: A first network device associated with a network may establish an Internet protocol version 6 Multiprotocol BGP session with a second network device associated with the network. The first network device and second network device are both capable of forwarding both IPv4 and IPv6 packets with only an IPv6 address configured on the interface of both the first network device and second network device. The first network device may exchange Multiprotocol Reachability capability with second network device for corresponding 2-tuple Address Family Identifier/Subsequent Address Family Identifier. The first network device may advertise Internet protocol version 4 network layer reachability information and may advertise Internet protocol version 6 network layer reachability information with IPv6 extended next hop encoding using Internet Assigned Numbering Authority assigned capability code value 5 to second network device.

Abstract: A system is disclosed allowing a buyer to directly build a shopping cart(s) on a supplier's portal (such as website, applications) without initiating any shopping request from company's network or system (such as eProcurement system). A standard cXML document can be used to transmit a Punchout Order Message (POOM) address to a customer system where the POOM can be retrieved. Additionally, a buyer identifier (e.g., an email address) can be included in the cXML document so that the customer system can verify the buyer making purchases. An address is returned to the supplier's portal, which can be used by the buyer to complete the purchase. In one example, the address directs the buyer to log into the customer system to verify the purchase.

Abstract: A first network device associated with a network may establish an Internet protocol version 6 Multiprotocol BGP session with a second network device associated with the network. The first network device and second network device are both capable of forwarding both IPv4 and IPv6 packets with only an IPv6 address configured on the interface of both the first network device and second network device. The first network device may exchange Multiprotocol Reachability capability with second network device for corresponding 2-tuple Address Family Identifier/Subsequent Address Family Identifier. The first network device may advertise Internet protocol version 4 network layer reachability information and may advertise Internet protocol version 6 network layer reachability information with IPv6 extended next hop encoding using Internet Assigned Numbering Authority assigned capability code value 5 to second network device.

Abstract: Disclosed are various embodiments for self-service integration and feature testing. In one embodiment, a test mode service receives a request to test an integration of a third-party system with a production system. The test mode service enables at least one plugin to test at least one function of the production system. The test mode service executes at least one function using the plugin(s) and data provided by the integration of the third-party system. The test mode service then reports a result of how the production system performs the function(s) associated with the plugin(s) using test data.

Abstract: In B2B purchasing, ordering is proposed wherein a customer can buy directly from a supplier website without logging into their own E-procurement system. In one embodiment, the supplier website generates a customized purchase order (PO) for submission to a third-party's purchasing system based upon purchases made by the customer. The purchasing system sends an acknowledgement, and the supplier can proceed to fulfil the order.

Abstract: Disclosed are various embodiments for self-service integration and feature testing. In one embodiment, a test mode service receives a request to test an integration of a third-party system with a production system. The test mode service enables at least one plugin to test at least one function of the production system. The test mode service executes at least one function using the plugin(s) and data provided by the integration of the third-party system. The test mode service then reports a result of how the production system performs the function(s) associated with the plugin(s) using test data.

Abstract: The present invention relates to the field of cancer therapy. Specifically, provided are methods of neoadjuvant therapies or adjuvant therapies to treat squamous cell carcinoma in a subject with a farnesyltransferase inhibitor (FTI) that include determining whether the subject is likely to be responsive to the FTI treatment based on the H-Ras mutant allele frequency.

Abstract: A system is disclosed allowing a customer to directly build a shopping cart on a supplier's website without logging into a third-party eProcurement system for which the customer is making purchases. Various push and pull models are used for allowing the customer to request content of shopping cart. After the customer logs into the supplier's website, the customer can be identified as associated with the third-party eProcurement system. In such a case, the user is displayed a control allowing the shopping cart to be transmitted to the third-party system for approval.

Abstract: The method includes an IT custom-defined chargeback system which makes service consumer and revenue producing business unites aware of the costs of IT. This custom defined chargeback model allows to control escalating cost, improve decision-making, align behavior with organizational goals and lead to effective use of it. Service consumer selects the cloud plans based on cloud pricing and requirement of resources. User consumes all these resources under the supervision of cloud brain. If consumer crosses threshold value of resources consumption or cost, an alerts messages sent to managers and they take appropriate decision so that cloud resources should get used efficiently. Threshold validation and cloud bill assessment plays as very important role which gives clear cut idea about cloud resources consumption by each team. Admin analyze the monthly cloud bills and generates team wise chargeback reports.

Abstract: This invention will be used to determine how ready a user is to begin migrating their workload to a Cloud. Each client will provide some general information about the workload they wish to migrate. Based on the user's responses, a data visualization—in the form of a meter—will be formulated to determine the user's readiness score. Additionally, this tool will help the user better understand their unique challenges or issues that must be resolved before migration can occur. A cloud readiness report is generated at the end of this process, which will tell the user the specific issues that may hinder their migration process. With the help of invention, users can cut down their time and cost for checking their cloud readiness status. This tool will assist clients to identify any issues that would interfere with their migration to a cloud.

Abstract: Novel metallic systems and methods for their fabrication provide an extreme creep-resistant nano-crystalline metallic material. The material comprises a matrix formed of a solvent metal with crystalline grains having diameters of no more than about 500 nm, and a plurality of dispersed metallic particles formed on the basis of a solute metal in the solvent metal matrix and having diameters of no more than about 200 nm. The particle density along the grain boundary of the matrix is as high as about 2 nm2 of grain boundary area per particle so as to substantially block grain boundary motion and rotation and limit creep at temperatures above 35% of the melting point of the material.

Abstract: A multi-layer structure comprising: (a) a skin layer comprising at least 50% by weight of an ethylene/?-olefin interpolymer composition (LLDPE) having a Comonomer Distribution Constant (CDC) in the range of from 45 to 400, and wherein the skin layer does not contain any migratory additive; (b) a metal layer disposed on the skin layer to form a metalized film; and (c) at least one substrate layer laminated onto the metallized film; wherein the ethylene/?-olefin interpolymer composition comprises (i) less than or equal to 100 percent by weight of the units derived from ethylene; and (ii) less than 30 percent by weight of units derived from one or more ?-olefin comonomers is provided.

Abstract: Novel metallic systems and methods for their fabrication provide an extreme creep-resistant nano-crystalline metallic material. The material comprises a matrix formed of a solvent metal with crystalline grains having diameters of no more than about 500 nm, and a plurality of dispersed metallic particles formed on the basis of a solute metal in the solvent metal matrix and having diameters of no more than about 200 nm. The particle density along the grain boundary of the matrix is as high as about 2 nm2 of grain boundary area per particle so as to substantially block grain boundary motion and rotation and limit creep at temperatures above 35% of the melting point of the material.