Abstract: Provided herein are compounds of Formulas (la), (lb), (II) to (VIII), and salts thereof, and methods of making the same. Also provided herein are recombinant proteins useful in the production of compounds disclosed herein, polynucleotides encoding the same, and cells comprising the same.

Abstract: An orthopaedic surgical system includes a sensor module for determining the joint force of a patient's knee joint and an adaptor for coupling various tibial trialing components to the sensor module. The sensor module includes a tibial paddle to which the adaptor is configured to couple. The adaptor and tibial paddle include structures that control the orientation at which the adaptor is attachable to the tibial paddle. Some tibial trialing components may be positioned over the adaptor in a mobile orientation that facilities rotation of the tibial trialing component relative to the tibial paddle or a fixed orientation that restricts the rotation of the tibial trialing component.

Abstract: A method for detecting computer issues includes identifying a target computer system. A first set of data for a first time period relating an operating metric from the target computer system are received. The operating metric is stored. A second set of data for a second time period relating to the operating metric is received. The first and second sets of data are compared. A difference between the two sets of data is identified. If the difference between the two sets of data is within a range a warning notification is displayed in a graphical user interface. An input is received in the graphical user interface in response to the warning notification being displayed.

Abstract: The disclosure relates to a method of making at least one cannabinoid comprising contacting at least one berberine bridge enzyme like (BBE-like) oxidase with at least one substrate, wherein the substrate comprises a cannabinoid precursor. The cannabinoid precursor can include cannabigerolic acid dihydrotetrachlorizine, prechlorizidine, cannabigerorcinic acid, grifolic acid, or a combination thereof.

Abstract: Provided herein are compositions and methods for mechanochemical dynamic therapy.

Abstract: Provided herein are compositions and methods for remotely and non-invasively subjecting targeted biological structures with light emissions or chromogenic changes.

Abstract: This disclosure provides for compositions and methods that can be used to predict an individual's risk for experiencing a cardiovascular event following a surgical procedure (e.g., a non-cardiac surgical procedure).

Abstract: Embodiments include a method of using inactivated human cold coronaviruses (HCoVs) particularly HCoV-299E, HCoV-OC43, HCoV-NL63 and HCoV-HKU1 as a booster, for the immunization against SARS-CoV-2 infections.

Abstract: A coupling for interconnecting a first pipe element and a second pipe element. The coupling comprises a first coupling member on the first pipe element, and a second coupling member on the second pipe element. The second coupling member is dimensioned to receive therein the first coupling member. The coupling also includes a retainer element having threads to engage the first coupling member to retain the first and second coupling members in a coupled state. The retainer element includes a lock feature to prevent inadvertent loosening rotation.

Abstract: Provided herein are compositions and methods for remotely and non-invasively subjecting targeted biological structures with light emissions or chromogenic changes.

Abstract: Provided herein are compounds of Formulas (la), (lb), (II) to (VIII), and salts thereof, and methods of making the same. Also provided herein are recombinant proteins useful in the production of compounds disclosed herein, polynucleotides encoding the same, and cells comprising the same.

Abstract: Disclosed are methods, systems, components, and compositions for synthesis of sequence defined polymers. The methods, systems, components, and compositions may be utilized for incorporating novel substrates that include non-standard amino acid monomers and non-amino acid monomers into sequence defined polymers. As disclosed herein, the novel substrates may be utilized for acylation of tRNA via flexizyme catalyzed reactions. The tRNAs thus acylated with the novel substrates may be utilized in synthesis platforms for incorporating the novel substrates into a sequence defined polymer.

Abstract: A battery module for construction of a battery pack includes a battery sealed in a rectangular housing with front and rear open ends closed by front and rear plates, respectively. The rear plate includes a plurality of rear plate bores in axial alignment with a plurality of housing bores proximal the rear open end of the housing. The front plate includes a plurality of front plate bores in axial alignment with a plurality of housing bores proximal the front open end of the housing. The front plate additionally includes positive and negative terminals electrically connected to the battery.

Abstract: The present invention in an embodiment relates generally to mask/respirator having a filter assembly detachable therefrom.

Abstract: A method of spontaneously patterning a polymer during frontal polymerization includes activating an initiation region of a monomer solution to reaction to initiate a polymerization reaction. A polymerization front is generated and propagates through the monomer solution in a radial or longitudinal direction away from the initiation region. The monomer solution is spontaneously heated downstream of the polymerization front by thermal transport away from the polymerization reaction. Once a localized region of the monomer solution reaches a temperature sufficient for spontaneous initiation of another polymerization reaction, a new polymerization front is generated and propagates through the monomer solution in a circumferential or transverse direction.

Abstract: A large-scale radio frequency signal collection and processing system comprising a plurality of sensor systems mounted on a plurality of collection platforms that integrates a plurality of overlapping datasets with differing characteristics (e.g., different resolutions, different view angles, different heights, different time periods, unrelated types of data) to generate an enriched dataset or datasets using a variety of processing techniques (e.g., statistical analysis, signal processing, image processing) that allows for more comprehensive analysis of the radio frequency signal landscape than would be possible using any of the datasets individually, or in combination but without such integration.

Abstract: A method for detecting computer issues includes identifying a target computer system. A first set of data for a first time period relating an operating metric from the target computer system are received. The operating metric is stored. A second set of data for a second time period relating to the operating metric is received. The first and second sets of data are compared. A difference between the two sets of data is identified. If the difference between the two sets of data is within a range a warning notification is displayed in a graphical user interface. An input is received in the graphical user interface in response to the warning notification being displayed.

Abstract: An energetic composition and a method of unzipping polymer binders are disclosed, which includes localizing a heat feedback just near the reaction front by unzipping polymer binders employed to a nanothermite. The energetic composition includes an unzipping polymer binder employed to high load fuel and oxidizer particles.