Patents by Inventor Sándor Demkó

Sándor Demkó has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthesis of sialooligosaccharide derivatives
    Patent number: 9102966
    Abstract: The invention relates to a method for the synthesis of compounds of general formula (1A) and salts thereof wherein one of the R groups is an ?-sialyl moiety and the other is H, X1 represents a carbohydrate linker, A is a D-glucopyranosyl unit optionally substituted with fucosyl, R1 is a protecting group that is removable by hydrogenolysis, the integer m is 0 or 1, by a transsialidation reaction.
    Type: Grant
    Filed: July 15, 2011
    Date of Patent: August 11, 2015
    Assignee: GLYCOM A/S
    Inventors: Andreas Schroven, Elise Champion, Gyula Dekany, Christoph Röhrig, Ioannis Vrasidas, Ignacio Figueroa Pérez, Markus Hederos, Julien Boutet, Ágnes Ágoston, Piroska Kovács-Pénzes, Ferenc Horváth, Christian Risinger, Gergely Pipa, Sándor Demkó, Lars Kröger
  • Method for preparation of the tetrasaccharide lacto-N-neotetraose (LNnt) containing N-acetyllactosamine
    Patent number: 8993740
    Abstract: The present invention relates to a method for preparation of the tetrasaccharide lacto-N-neotetraose (LNnt, formula (I)) especially in large scale, as well as intermediates in the synthesis, a new crystal form (polymorph) of LNnt, and the use thereof in pharmaceutical or nutritional compositions.
    Type: Grant
    Filed: February 21, 2011
    Date of Patent: March 31, 2015
    Assignee: Glycom A/S
    Inventors: István Bajza, Gyula Dekany, Károly Ágoston, Ignacio Figuero-Pérez, Julien Boutet, Markus Hederos, Ferenc Horváth, Piroska Kovács-Pénzes, Lars Kröger, Christoph Röhrig, Andreas Schroven, Ioannis Vrasidas, Péter Trinka, László Kalmár, Irme Kovács, Sándor Demkó, Ágnes Ágoston, Christian Risinger
  • Synthesis of the Trisaccharide 3-O-Fucosyllactose and Intermediates Thereof
    Publication number: 20150065702
    Abstract: 3-O-Fucosyllactose is made by process which includes the hydrogenolysis of a new compound of the formula 1 wherein R1 and R2 are independently a group removable by hydrogenolysis, and R3 is a group removable by hydrogenolysis or H; or a hydrate or solvate thereof.
    Type: Application
    Filed: March 20, 2013
    Publication date: March 5, 2015
    Inventors: Christoph Röhrig, Gyula Dekany, Martin Matwiejuk, Sándor Demkó
  • Method for crystallization of fucose
    Patent number: 8901291
    Abstract: The present application discloses a method for the crystallization of fucose, characterized in that the crystallization is carried out from a mixture comprising fucose and at least one 6-deoxy sugar selected from 6-deoxy-talose and 6-deoxy-gulose. In one embodiment, the mixture comprises fucose and 6-deoxy-talose.
    Type: Grant
    Filed: May 19, 2011
    Date of Patent: December 2, 2014
    Assignee: Glycom A/S
    Inventors: Julien Boutet, Gyula Dekany, Ágnes Jànosi, Gergely Pipa, Ferenc Horvàth, Krisztián Kovàcs, Ignacio Pérez Figueroa, Markus Hederos, Andreas Schroven, Ioannis Vrasidas, Piroska Kovács-Pénzes, Christian Risinger, Sándor Demkò, Lars Kröger, Christoph Röhrig
  • Polymorphs of 2?-O-fucosyllactose and producing thereof
    Patent number: 8889637
    Abstract: The present invention relates to novel polymorphs of the trisaccharide 2?-O-fucosyllactose (2-FL) of formula (1), methods for producing said polymorphs and their use in pharmaceutical or nutritional compositions.
    Type: Grant
    Filed: June 1, 2011
    Date of Patent: November 18, 2014
    Assignee: Glycom A/S
    Inventors: Károly Ágoston, István Bajza, Gyula Dekany, Péter Trinka, Ágnes Ágoston, Gábor Kádár, Sándor Demkó, Ignacio Figueroa-Pérez, Markus Hederos, Ferenc Horváth, Andreas Schroven, Ioannis Vrasidas, Piroska Kovács-Pénzes, Christian Risinger, László Kalmár, Gergely Pipa, Julien Boutet, Lars Kröger, Christoph Röhrig
  • MANUFACTURE OF LACTO-N-TETRAOSE
    Publication number: 20140323705
    Abstract: The present invention relates to the synthesis of the tetrasaccharide of formula (I) and novel intermediates used in the synthesis.
    Type: Application
    Filed: May 14, 2012
    Publication date: October 30, 2014
    Inventors: Markus Hederos, Gyula Dekany, Sándor Demkó, Imre Kovács, István Bajza
  • SYNTHESIS OF HMO CORE STRUCTURES
    Publication number: 20140235850
    Abstract: The invention relates to a method for making precursors of HMO core structures comprising a step of reacting an N-acetyllactosamine or lacto-N-biose derivative donor with a lactose or N-acetyllactosamine derivative acceptor, wherein the donor is an oxazoline donor.
    Type: Application
    Filed: October 1, 2012
    Publication date: August 21, 2014
    Inventors: Imre Kovács, István Bajza, Markus Hederos, Gyula Dekany, Sándor Demkó, Nikolay Khanzhin
  • CATALYTIC HYDROGENOLYSIS OF A COMPOSITION OF A MIXTURE OF OLIGOSACCHARIDE PRECURSORS AND USES THEREOF
    Publication number: 20140057868
    Abstract: A method for the manufacture of a mixture of human milk oligosaccharides is disclosed. The method involves the catalytic hydrogenolysis of compounds of the general formula 1 and 2. The use of compounds of general formula 1 and 2 in the manufacture of human milk oligosaccharides is also disclosed.
    Type: Application
    Filed: February 21, 2012
    Publication date: February 27, 2014
    Applicant: GLYCOM A/S
    Inventors: Gyula Dekany, Sandor Demkó, Andreas Schroven, Elise Champion
  • SYNTHESIS OF NEW SIALOOLIGOSACCHARIDE DERIVATIVES
    Publication number: 20130171696
    Abstract: The invention relates to a method for the synthesis of compounds of general formula (1A) and salts thereof wherein one of the R groups is an ?-sialyl moiety and the other is H, X1 represents a carbohydrate linker, A is a D-glucopyranosyl unit optionally substituted with fucosyl, R1 is a protecting group that is removable by hydrogenolysis, the integer m is 0 or 1, by a transsialidation reaction.
    Type: Application
    Filed: July 15, 2011
    Publication date: July 4, 2013
    Applicant: Glycom A/S
    Inventors: Andreas Schroven, Elise Champion, Gyula Dekany, Christoph Röhrig, Ioannis Vrasidas, Ignacio Figueroa Pérez, Markus Hederos, Julien Boutet, Ágnes Ágoston, Piroska Kovács-Pénzes, Ferenc Horváth, Christian Risinger, Gergely Pipa, Sándor Demkó, Lars Kröger
  • DERIVATIZATION OF OLIGOSACCHARIDES
    Publication number: 20130172548
    Abstract: A method for purifying, separating and/or isolating an oligosaccharide or a salt thereof is presented. An embodiment of the invention is based upon the formation of anomeric O-benzyl/substituted O-benzyl derivatives in a selective anomeric alkylation reaction.
    Type: Application
    Filed: July 15, 2011
    Publication date: July 4, 2013
    Applicant: Glycom A/S, Kgs.
    Inventors: Gyula Dekany, Istvan Bajza, Károly Ágoston, Ignacio Figueroa Pérez, Markus Hedros, Andreas Schroven, Ioannis Vrasidas, Julien Boutet, Lars Kröger, Christoph Röhrig, Imre Kovacs, Péter Trinka, Ágnes Ágoston, Piroska Kovács-Pénzes, Ferenc Horváth, Christian Risinger, Gergely Pipa, Sándor Demkó, László Kalmár, Elise Champion
  • POLYMORPHS OF 2'-O-FUCOSYLLACTOSE AND PRODUCING THEREOF
    Publication number: 20130165406
    Abstract: The present invention relates to novel polymorphs of the trisaccharide 2?-O-fucosyllactose (2-FL) of formula (1), methods for producing said polymorphs and their use in pharmaceutical or nutritional compositions.
    Type: Application
    Filed: June 1, 2011
    Publication date: June 27, 2013
    Applicant: Glycom A/S
    Inventors: Károly Ágoston, István Bajza, Gyula Dekany, Péter Trinka, Ágnes Ágoston, Gábor Kádár, Sándor Demkó, Ignacio Figueroa Pérez, Markus Hederos, Ferenc Horváth, Andreas Schroven, Ioannis Vrasidas, Piroska Kovács-Pénzes, Christian Risinger, László Kalmár, Gergely Pipa, Julien Boutet, Lars Kröger, Christoph Röhrig
  • METHOD FOR CYRSTALLIZATION OF FUCOSE
    Publication number: 20130072675
    Abstract: The present application discloses a method for the crystallization of fucose, characterized in that the crystallization is carried out from a mixture comprising fucose and at least one 6-deoxy sugar selected from 6-deoxy-talose and 6-deoxy-gulose. In one embodiment, the mixture comprises fucose and 6-deoxy-talose.
    Type: Application
    Filed: May 19, 2011
    Publication date: March 21, 2013
    Applicant: GLYCOM A/S
    Inventors: Julien Boutet, Gyula Dekany, Ágnes Jánosi, Gergely Pipa, Ferenc Horváth, Krisztián Kovács, Ignacio Pérez Figueroa, Markus Hederos, Andreas Schroven, Ioannis Vrasidas, Piroska Kovács-Pénzes, Christian Risinger, Sándor Demkó, Lars Kröger, Christoph Röhrig
  • METHOD FOR PREPARATION OF THE TETRASACCHARIDE LACTO-N-NEOTETRAOSE (LNNT) CONTAINING N-ACETYLLACTOSAMINE
    Publication number: 20120309949
    Abstract: The present invention relates to a method for preparation of the tetrasaccharide lacto-N-neotetraose (LNnt, formula (I)) especially in large scale, as well as intermediates in the synthesis, a new crystal form (polymorph) of LNnt, and the use thereof in pharmaceutical or nutritional compositions.
    Type: Application
    Filed: February 21, 2011
    Publication date: December 6, 2012
    Applicant: GLYCOM A/S
    Inventors: István Bajza, Gyula Dekany, Károly Ágoston, Ignacio Pérez Figueroa, Julien Boutet, Markus Hederos, Ferenc Horváth, Piroska Kovács-Pénzes, Lars Kröger, Christoph Röhrig, Andreas Schroven, Ioannis Vrasidas, Péter Trinka, László Kalmár, Irme Kovács, Sándor Demkó, Ágnes Ágoston, Christian Risinger