Abstract: Systems and methods for asynchronous data communication are disclosed. The system includes one or more peripheral devices, a processing device, and one or more communication channels. Each peripheral device includes a peripheral clock and a quantizer. The processing device is remotely located from each peripheral device and includes a processor clock that is asynchronous with at least one peripheral clock, an analog continuous time filter, and an analog-to-digital converter. The analog continuous time filter filters one or more quantized signals generated by the one or more peripheral devices to generate one or more filtered signals. The analog continuous time filter has a filter bandwidth corresponding to a signal bandwidth of one or more analog time varying signals represented by the one or more quantized signals. The analog-to-digital converter generates one or more converted signals by sampling the one or more filtered signals based on a processor clock signal.

Abstract: The present invention relates to subtilase variants suitable for use in, e.g., cleaning or detergent compositions, such as laundry detergent compositions and dish wash compositions, including automatic dish wash compositions. The present invention also relates to isolated DNA sequences encoding the variants, expression vectors, host cells, and methods for producing and using the variants of the invention.

Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.

Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.

Abstract: Systems and methods for controlling heating of a hydrocarbon medium using a signal generator and a load having frequency and time dependent impedance. A desired heating life cycle is determined. A current state is determined using a model of the medium and the load. A desired operational state is determined from the current operational state and the desired heating life cycle. The desired operational state is selected to maximize a fit between the desired operational state and the desired heating life cycle. Desired signal generator control settings are determined for the signal generator in order to achieve the desired operational state. An output signal is generated using the signal generator by applying the at least one desired signal generator control setting to the signal generator. The output signal is defined to excite the load and thereby heat the hydrocarbon medium.

Abstract: A method of manufacturing a surgical device including providing a substrate having opposite first and second sides. The second side having a first section and a second section. Coupling a substrate to a fixture such that the first side faces the fixture and depositing a gel onto the second side such that the gel coats the first section without coating the second section.

Abstract: A signal generator, system, and method for electromagnetically heating of a hydrocarbon formation. The method involves determining a desired output signal having a desired power spectral density; generating a plurality of source signals, based on the desired output signal; modulating the plurality of source signals, based on the desired output signal, to provide a plurality of modulated signals capable of providing the desired power spectral density; combining one or more of the plurality of modulated signals into a combined signal; transforming the combined signal to have the desired power spectral density, thereby providing at least one output signal; and applying the at least one output signal to a load having a frequency-dependent impedance to produce at least one standing electromagnetic wave along a length of the load. The at least one standing electromagnetic wave includes at least a partial standing electromagnetic wave.

Abstract: Various embodiments of a hermetically-sealed package and a method of forming such package are disclosed. The package includes a housing that extends along a housing axis between a first end and a second end, where the housing includes first and second opaque portions and a transparent portion disposed between the first and second opaque portions. The first opaque portion is hermetically sealed to a first end of the transparent portion and the second opaque portion is hermetically sealed to a second end of the transparent portion. At least one of the first and second opaque portions is hermetically sealed to the transparent portion by a weld ring. The package further includes a power source disposed within the housing, and an inductive coil disposed at least partially within the transparent portion of the housing and electrically connected to the power source.

Abstract: Systems, devices and methods allow inductive recharging of a power source located within or coupled to an implantable medical device while the device is implanted in a patient. The implantable devices in some examples include a multi-axis antenna having a plurality of coil windings arranged orthogonal to one another. The multi-axis antenna configured to generate at least a minimum level of induced current for recharging a power source of the implanted medical device regardless of the orientation of a direction of a magnetic field imposed on the multi-axis antenna relative to an orientation of the implanted medical device and the multi-axis antenna for a given energy level of the imposed magnetic field.

Abstract: A door for an entryway includes an exterior-facing surface, an inner structure, and a latch mechanism. The latch mechanism is connected to the inner structure and configured to be fastened or released for controlling access to the entryway. The door also includes a key-cylinder accessible from the exterior-facing surface and configured to selectively lock and unlock the latch mechanism. The door additionally includes a pawl configured to be rotated by the key-cylinder about a pivot axis, connected to the latch mechanism, and defining a pass-through aperture distal from the pivot axis. The door also includes a shield defining a shield attachment aperture and connected to the inner structure. The door further includes a security fastener to fix the shield relative to the key-cylinder at the shield attachment aperture and extending through the pass-through aperture without impeding the pawl's rotation or contacting the pawl as the pawl operates the latch mechanism.

Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.

Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.

Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.

Abstract: A medical device system for delivering a neuromodulation therapy includes a delivery tool for deploying an implantable medical device at a neuromodulation therapy site. The implantable medical device includes a housing, an electronic circuit within the housing, and an electrical lead comprising a lead body extending between a proximal end coupled to the housing and a distal end extending away from the housing and at least one electrode carried by the lead body. The delivery tool includes a first cavity for receiving the housing and a second cavity for receiving the lead. The first cavity and the second cavity are in direct communication for receiving and deploying the housing and the lead coupled to the housing concomitantly as a single unit.

Abstract: A method of forming an implant includes positioning a first mesh component of the implant within a second mesh component of the implant to form an implant assembly. The implant assembly is manipulated to join the first mesh component with the second mesh component.

Abstract: Systems and methods for controlling heating of a hydrocarbon medium using a signal generator and a load having frequency and time dependent impedance. A desired heating life cycle is determined. A current state is determined using a model of the medium and the load. A desired operational state is determined from the current operational state and the desired heating life cycle. The desired operational state is selected to maximize a fit between the desired operational state and the desired heating life cycle. Desired signal generator control settings are determined for the signal generator in order to achieve the desired operational state. An output signal is generated using the signal generator by applying the at least one desired signal generator control setting to the signal generator. The output signal is defined to excite the load and thereby heat the hydrocarbon medium.

Abstract: Various embodiments of a sealed package and a method of forming such package are disclosed. The package includes a housing having an inner surface and an outer surface, a dielectric substrate having a first major surface and a second major surface, and a dielectric bonding ring disposed between the first major surface of the dielectric substrate and the housing, where the dielectric bonding ring is hermetically sealed to both the first major surface of the dielectric substrate and the housing. The package further includes an electronic device disposed on the first major surface of the dielectric substrate, and a power source disposed at least partially within the housing and electrically connected to the electronic device.

Abstract: Systems, devices and methods allow inductive recharging of a power source located within or coupled to an implantable medical device while the device is implanted in a patient. The recharging system/device in some examples includes a first electrical coil and a second electrical coil configured to generate opposing magnetic fields forming a resultant magnetic field within a recharging envelope located between the coils. A third coil of the implantable medical device may be positioned within the recharging envelope so that the resultant magnetic field is imposed on the third coil, causing electrical energy to be induced in the third coil, the induced electrical energy used to recharge a power source of an implantable medical device coupled to the third coil, and/or to power operation of the implantable medical device.

Abstract: An implantable medical device (IMD) has a housing enclosing an electronic circuit. The housing includes a first housing portion, a second housing portion and a joint coupling the first housing portion to the second housing portion. A polymer seal is positioned in the joint in various embodiments. Other embodiments of an IMD housing are disclosed.

Abstract: Separator and electrolyte composites include a porous self-supporting separator film between or adjacent one or two electrolyte films. The electrolyte films may contain a glyme or mixture of glymes, LiX salt and complexing agent, such as PEO. The porous self-supporting separator film may be used dry or wetted with a liquid electrolyte composition. Solid state batteries include the described separator and electrolyte composites in combination with an anode and a cathode.