Abstract: A system and method for simulating injury treatment on a living body are provided. The system includes an embedded system configured to be placed on a living body and to simulate an injury of the living body in response to instructions received from a simulation system. Sensors detect a parameter corresponding to a treatment of said injury and transmit said parameter to said simulation system which transmit the instructions to the embedded system to cause it to simulate the injury. The simulation system is further configured to receive sensor data representing the parameter detected by the sensors and the treatment of the injury, and to execute a simulation scenario, which associates the detected parameter with a corresponding effect on the injury. Furthermore, the simulation system is configured to send instructions to the embedded system, which cause the embedded system to simulate the injury such that the simulation reflects the treatment.

Abstract: A system and method for simulating injury treatment on a living body are provided. The system includes an embedded system configured to be placed on a living body and to simulate an injury of the living body in response to instructions received from a simulation system. Sensors detect a parameter corresponding to a treatment of said injury and transmit said parameter to said simulation system which transmit the instructions to the embedded system to cause it to simulate the injury. The simulation system is further configured to receive sensor data representing the parameter detected by the sensors and the treatment of the injury, and to execute a simulation scenario, which associates the detected parameter with a corresponding effect on the injury. Furthermore, the simulation system is configured to send instructions to the embedded system, which cause the embedded system to simulate the injury such that the simulation reflects the treatment.

Abstract: The invention relates to a porous hydrogel matrix having substantially interconnected tunnel-shaped micropores with a three-dimensional configuration of an interconnected hollow tetrapod network. Such matrices may be used to entrap motile cells that migrate into the micropores of said matrix. The matrices of the invention are formed by a method comprising the steps of providing a solution of a hydrogel-forming material, providing a template material with a three-dimensional configuration corresponding to the negative configuration of the desired interconnected porous structure of the hydrogel material, said template material comprising interconnected zinc oxide tetrapod (t-ZnO) networks, casting the solution of hydrogel-forming material onto the template and removing the template material from the hydrogel material by acid hydrolysis of the template material.

Abstract: The invention relates to a porous hydrogel matrix having substantially interconnected tunnel-shaped micropores with a three-dimensional configuration of an interconnected hollow tetrapod network. Such matrices may be used to entrap motile cells that migrate into the micropores of said matrix. The matrices of the invention are formed by a method comprising the steps of providing a solution of a hydrogel-forming material, providing a template material with a three-dimensional configuration corresponding to the negative configuration of the desired interconnected porous structure of the hydrogel material, said template material comprising interconnected zinc oxide tetrapod (t-ZnO) networks, casting the solution of hydrogel-forming material onto the template and removing the template material from the hydrogel material by acid hydrolysis of the template material.

Abstract: The invention relates to aqueous pharmaceutical formulations comprising human growth hormone, histidine, poloxamer, phenol, and mannitol.

Abstract: This invention relates to novel compounds, methods for selective chemical conjugation of protractor molecules and the use thereof for diagnostic and/or therapeutic purposes.

Abstract: The present invention relates to novel coagulation Factor VII polypeptides, polynucleotide constructs encoding such polypeptides, as well as vectors and host cells comprising and expressing the polynucleotide, pharmaceutical compositions, uses and methods of treatment.

Abstract: The invention relates to aqueous pharmaceutical formulations comprising human growth hormone, histidine, poloxamer, phenol, and mannitol.

Abstract: A parenterally administrable, biodegradable microparticle preparation containing a biologically active substance which, during the first 24 hours after injection, exhibits a release of the active substance that is less than 25% of the total release, determined from a concentration-time curve in the form of the ratio between the area under the curve during the said first 24 hours and the total area under the curve in question

Abstract: The present invention relates to aprotinin variants having improved enzyme-inhibitory, immunological and pharmacokinetic properties and their preparation.