Abstract: The present invention relates to hAM15-52 analogues with improved amylin receptor (hAMY3R) potency (hAMY3R-EC50?250 pM) and which are largely based on the sequence of the human adrenomedullin fragment hAM15-52. The invention further relates to hAM15-52 analogues that are selective amylin receptor (hAMY3R) agonists (hAMY3R-EC50?250 pM and an hAM1R-EC50?25 nM) and which are largely based on the sequence of the human adrenomedullin fragment hAM15-52. The hAM15-52 analogues according to the invention maintain the good physical stability of hAM15-52. The invention further relates to pharmaceutical compositions comprising such polypeptides and their use in the treatment of a medical condition such as obesity, NASH and/or diabetes.

Abstract: A mixer includes a mixing chamber and a motor mechanically connected to the mixing chamber. The mixing chamber comprises a suspended elongate rigid tube section having a top end and an open bottom end, and a flexible tube section extending downwards from the open bottom end. The motor comprises a vibration motor mechanically coupled to the suspended elongate rigid tube section at the top end of the suspended elongate rigid tube section.

Abstract: A communication system, a communication device and related method, the communication device comprising a processor, a source interface comprising a first source interface for a first external source, and an output interface, wherein the processor is configured to obtain, e.g. receive, a first input signal via the first source interface, obtain a first complementing signal, combine the first input signal and the first complementing signal to a first combined signal, apply a first filter function to the first combined signal for provision of a first left output signal and a first right output signal, the first filter function comprising one or more head related transfer functions, and output a left output signal and a right output signal via the output interface, wherein the left output signal is based on the first left output signal and the right output signal is based on the first right output signal.

Abstract: A communication system, a communication device and related method, the communication device comprising a processor, a source interface comprising a first source interface for a first external source, and an output interface, wherein the processor is configured to obtain, e.g. receive, a first input signal via the first source interface, obtain a first complementing signal, combine the first input signal and the first complementing signal to a first combined signal, apply a first filter function to the first combined signal for provision of a first left output signal and a first right output signal, the first filter function comprising one or more head related transfer functions, and output a left output signal and a right output signal via the output interface, wherein the left output signal is based on the first left output signal and the right output signal is based on the first right output signal.

Abstract: The present invention relates to an on-line method and a flow system as well as a cuvette for carrying out IR spectrometry for analysis of liquid food products, possibly containing dissolved gases, in a process line in a liquid food product processing plant, especially a dairy processing milk and milk products. A liquid sample is extracted from the process line to a measuring branch, the sample is thermostated and passed to a measurement cuvette. The IR-absorbance spectrum is measured, e.g. in the MID-IR or NIR-range. In order to obtain an on-line monitoring of the process line the liquid food sample is extracted directly from the process line into the measurement branch, in which the pressure is maintaining at least as high as in the adjacent process line. The high pressure ensures that dissolved air will stay dissolved in the liquid food. Before each new sample the measurement branch and cuvette are flushed by high flow rates with a part of the new sample to clean the cuvette.