Abstract: A therapeutic method of treatment of hemoglobinopathy by administration of a drug capable of blocking the Ca.sup.+2 channel in and out of muscle cells. Drugs known to possess this capability are 1,4-dihydropyridines, .beta.-phenethylamines, benzothiazepines, ethylenediamines and diaryl alkyl amines. These drugs are known to block the influx of Ca.sup.+2 into the cardiac muscle and are known to be useful in treatment of such heart muscle conditions as angina. It has now been unexpectedly discovered that such drugs can be used to treat hemoglobinopathy.

Abstract: A method of inhibiting the growth of malaria parasites in red blood cells not by affecting the parasites themselves but by affecting the metabolism of red blood cells. The method involves introducing and maintaining beta-adrenergic blockers or calmodulin antagonists in the blood stream at a concentration enough to suppress the parasite growth.