Patents by Inventor Saad Z. Usmani

Saad Z. Usmani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of determining IMiDS resistance in plasma cell disorders
    Patent number: 10697024
    Abstract: The present invention provides methods for determining immunomodulatory derivatives (IMiDs) resistance in a subject having a plasma cell disorder.
    Type: Grant
    Filed: November 22, 2017
    Date of Patent: June 30, 2020
    Assignee: The Charlotte-Mecklenburg Hospital Authority
    Inventors: Saad Z. Usmani, Qing Zhang, Manisha Bhutani
  • Immune profiling and minimal residue disease following stem cell transplantation in multiple myeloma
    Patent number: 10656144
    Abstract: The present invention provides methods for determining the level or status of minimal residue disease (MRD) in a multiple myeloma (MM) patient including analyzing peripheral natural killer (NK), NK-T and T cell distribution and/or activation, and quantifying inflammatory cytokines, chemokines and growth factors in a biological sample obtained from an MM patient to provide a peripheral immune profile; and obtaining a level or status of MRD in the MM patient from the peripheral immune profile, wherein if the peripheral immune profile exceeds a pre-determined threshold, the MM patient is positive for MRD.
    Type: Grant
    Filed: December 1, 2017
    Date of Patent: May 19, 2020
    Assignee: The Charlotte Mecklenburg Hospital Authority
    Inventors: Saad Z. Usmani, Manisha Bhutani, Qing Zhang, David M. Foureau
  • IMMUNE PROFILING AND MINIMAL RESIDUE DISEASE FOLLOWING STEM CELL TRANSPLANATION IN MULTIPLE MYELOMA
    Publication number: 20180156784
    Abstract: The present invention provides methods for determining the level or status of minimal residue disease (MRD) in a multiple myeloma (MM) patient including analyzing peripheral NK, NK-T and T cell distribution and/or activation, and quantifying inflammatory cytokines, chemokines and growth factors in a biological sample obtained from an MM patient to provide a peripheral immune profile; and obtaining a level or status of MRD in the MM patient from the peripheral immune profile, wherein if the peripheral immune profile exceeds a pre-determined threshold, the MM patient is positive for MRD.
    Type: Application
    Filed: December 1, 2017
    Publication date: June 7, 2018
    Inventors: Saad Z. Usmani, Manisha Bhutani, Qing Zhang, David M. Foureau
  • METHODS OF DETERMINING IMIDS RESISTANCE IN PLASMA CELL DISORDERS
    Publication number: 20180148796
    Abstract: The present invention provides methods for determining immunomodulatory derivatives (IMiDs) resistance in a subject having a plasma cell disorder.
    Type: Application
    Filed: November 22, 2017
    Publication date: May 31, 2018
    Inventors: Saad Z. Usmani, Qing Zhang, Manisha Bhutani