Patents by Inventor Saadiq El-Amin

Saadiq El-Amin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Muscle-Polymer Constructs for Bone Tissue Engineering
    Publication number: 20070250165
    Abstract: Bone grafting materials containing a polymer scaffold loaded with bone morphogenetic proteins and populated with muscle cells induced by the bone morphogenetic proteins to exhibit an osteoblastic phenotype and to synthesize bone tissue are provided. Also provided are methods for using these polymer scaffolds in bone grafting procedures.
    Type: Application
    Filed: June 21, 2007
    Publication date: October 25, 2007
    Inventors: Cato Laurencin, Helen Lu, Michelle Kofron, Saadiq El-Amin, Mohamed Attawia
  • Muscle-polymer constructs for bone tissue engineering
    Publication number: 20040115238
    Abstract: Bone grafting materials containing a polymer scaffold loaded with bone morphogenetic proteins and populated with muscle cells induced by the bone morphogenetic proteins to exhibit an osteoblastic phenotype and to synthesize bone tissue are provided. Also provided are methods for using these polymer scaffolds in bone grafting procedures.
    Type: Application
    Filed: January 28, 2004
    Publication date: June 17, 2004
    Inventors: Cato T. Laurencin, Helen H. Lu, Michelle D. Kofron, Saadiq El-Amin, Mohamed A. Attawia
  • Poly(organophosphazene) matrices for bone replacement
    Patent number: 6235061
    Abstract: A highly porous three-dimensional biodegradable poly(organophosphazene) matrix with hydrolytically unstable side chains is prepared and used as a scaffold for the growth of osteoblast cells. In a preferred embodiment, the poly(organophosphazene) includes between 10 and 90% hydrolytically unstable side chains including glucosyl, glyceryl, glyceryl, imidazolyl or ethoxy units, for example, poly[(methylphenoxy)(ethyl glycinato) phosphazene]. The addition of the glucosyl, glycinyl or glyceryl side chains to the polymer can also be used generally to enhance growth rates of cells adhered to the polymer, presumably through uptake and metabolism of the simple sugar or alcohol units.
    Type: Grant
    Filed: April 4, 1994
    Date of Patent: May 22, 2001
    Assignees: The Penn State Research Foundation, Massachusetts Institute of Technology
    Inventors: Cato T. Laurencin, Saadiq El-Amin, Archel M. A. Ambrosio, Shawn R. Pucher, Harry R. Allcock