Patents by Inventor Sabine Borngraeber

Sabine Borngraeber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for creating specific, high affinity nuclear receptor pharmaceuticals
    Patent number: 7302347
    Abstract: This invention pertains to agonists that activate nuclear receptors. These agonists include an extension that contacts a region of the nuclear receptor outside the native ligand binding pocket. Methods for producing, identifying and designing such agonists are included along with nuclear receptor agonist complexes and libraries of agonists.
    Type: Grant
    Filed: December 10, 2002
    Date of Patent: November 27, 2007
    Assignee: The Regents of the University of California
    Inventors: John D. Baxter, Thomas S. Scanlan, Robert J. Fetterick, Sabine Borngraeber, Paul Webb
  • Method for creating nuclear receptor activity modulating pharmaceuticals
    Publication number: 20040253648
    Abstract: Methods for screening, identifying and/or designing agents that modulate nuclear receptors are provided. These agents contact a site on a nuclear receptor involved in dimer/heterodimer formation, cofactor molecule interactions, and/or folding, which is termed the nuclear receptor dimer/heterodimer regulatory site (DHRS). Methods employing the DHRS are included, along with nuclear receptor:agent complexes and libraries of agents.
    Type: Application
    Filed: December 9, 2003
    Publication date: December 16, 2004
    Applicant: The Regents of the University of California
    Inventors: Robert J. Fletterick, Sabine Borngraeber, John D. Baxter, Thomas S. Scanlan, Grazia Chiellini, Paul Webb
  • Method for creating specific, high affinity nuclear receptor pharmaceuticals
    Publication number: 20040110154
    Abstract: This invention pertains to agonists that activate nuclear receptors. These agonists include an extension that contacts a region of the nuclear receptor outside the native ligand binding pocket. Methods for producing, identifying and designing such agonists are included along with nuclear receptor agonist complexes and libraries of agonists.
    Type: Application
    Filed: December 10, 2002
    Publication date: June 10, 2004
    Applicant: The Regents of the University of California
    Inventors: John D. Baxter, Thomas S. Scanlan, Robert J. Fetterick, Sabine Borngraeber, Paul Webb