Patents by Inventor Sabine Merx

Sabine Merx has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds and methods for assessment of microsatellite instability (MSI) status
    Patent number: 7662595
    Abstract: The present invention provides a method for assessment of the Microsatellite Instability (MSI) status of medically relevant conditions associated with MSI phenotype such as e.g. neoplastic lesions. The method is based on the analysis of a monomorphic T25 (CAT25) mononucleotide repeat located in the 3?-UTR of the Caspase 2 (CASP2) gene. Based on the determination of the length of the named mononucleotide repeat the presence or absence of MSI may be assessed. Determination of the length is performed in a single PCR procedure. Alternatively an enhanced assessment could be performed by combining the CAT25 marker with further markers such as BAT25 and BAT26 in a single multiplex PCR process.
    Type: Grant
    Filed: October 19, 2005
    Date of Patent: February 16, 2010
    Assignee: MTM Laboratories, AG
    Inventors: Peter Findeisen, Sabine Merx, Matthias Kloor, Magnus Von Knebel Doeberitz
  • Compounds and Methods for Assessment of Microsatellite Instability (Msi) Status
    Publication number: 20080096197
    Abstract: The present invention provides a method for assessment of the Microsatellite Instability (MSI) status of medically relevant conditions associated with MSI phenotype such as e.g. neoplastic lesions. The method is based on the analysis of a monomorphic T25 (CAT25) mononucleotide repeat located in the 3?-UTR of the Caspase 2 (CASP2) gene. Based on the determination of the length of the named mononucleotide repeat the presence or absence of MSI may be assessed. Determination of the length is performed in a single PCR procedure. Alternatively an enhanced assessment could be performed by combining the CAT25 marker with further markers such as BAT25 and BAT26 in a single multiplex PCR process.
    Type: Application
    Filed: October 19, 2005
    Publication date: April 24, 2008
    Inventors: Peter Findeisen, Sabine Merx, Matthias Kloor, Magnus Von Knebel Doeberitz