Patents by Inventor Sabrina Conoci

Sabrina Conoci has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210232901
    Abstract: An embodiment method includes segmenting at least one electrophysiological signal and producing a set of sampled waveforms, applying artificial neural network processing to the set of sampled waveforms and a set of randomly generated noise samples and producing at least one altered data pattern, the altered data pattern comprising the set of filtered waveforms altered as a function of the randomly generated noise samples, providing calibration data comprising expected waveforms for filtered waveforms in the set of filtered waveforms, applying classifier processing to the produced at least one altered data pattern to detect a degree of resemblance between the produced at least one altered data pattern and the calibration data patterns, the classifier processing producing classification signals having values above or below at least one threshold value as a function of the detected degree of resemblance, and triggering a user circuit as a function of the classification signal.
    Type: Application
    Filed: January 22, 2021
    Publication date: July 29, 2021
    Inventors: Francesco Rundo, Sabrina Conoci, Concetto Spampinato
  • Patent number: 10987007
    Abstract: A method of processing electrophysiological signals includes: receiving, over a limited time duration, sample electrocardiography (ECG) signals indicative of heart pulsatile activity occurring with a variable heart rate, wherein receiving the sample ECG signals is discontinued at an expiry of the limited time duration; receiving photoplethysmography (PPG) signals indicative of the heart pulsatile activity; determining a correlation between the sample ECG signals and the PPG signals; determining reconstructed ECG signals from the PPG signals as a function of the correlation between the sample ECG signals and the PPG signals; and estimating a heart rate variability of the variable heart rate as a function of the reconstructed ECG signals.
    Type: Grant
    Filed: October 23, 2018
    Date of Patent: April 27, 2021
    Assignee: STMicroelectronics S.R.L.
    Inventors: Francesco Rundo, Sabrina Conoci, Piero Fallica
  • Publication number: 20210068739
    Abstract: An embodiment method comprises collecting at least one electrophysiological signal of a human over a limited time duration, and computing a set of electrophysiological signal features. The computing comprises at least one of: providing at least one reference electrophysiological signal and applying dynamic time warping processing to the at least one collected and at least one reference electrophysiological signals, applying stacked-auto-encoder artificial neural network processing to the collected electrophysiological signal, or filtering the electrophysiological signal collected via joint low-pass and high-pass filtering. The method further comprises applying pattern recognition processing to the computed set of features, producing a virtual key signal indicative of an identity of the human, and applying the virtual key signal to a user circuit to switch it between a first state and a second state as a result of the virtual key signal matching an authorized key signal stored in the user circuit.
    Type: Application
    Filed: September 1, 2020
    Publication date: March 11, 2021
    Inventors: Francesco Rundo, Sabrina Conoci, Concetto Spampinato
  • Publication number: 20200330020
    Abstract: In an embodiment, a method of processing an electrophysiological signal includes collecting the electrophysiological signal that is indicative of a level of attention of a human; filtering the electrophysiological signal via joint low-pass and high-pass filtering using a set of filtering parameters including low-pass filters parameters and high-pass filters parameters having a set of low-pass cut-off frequencies and a set of high-pass cut-off frequencies respectively. The method further includes applying artificial neural network processing to the filtered electrophysiological signal to extract therefrom a set of features of the electrophysiological signal. The method further includes applying classifier processing to the set of features extracted from the filtered electrophysiological signal and producing a classification signal indicative of the level of attention of the human. The method further includes generating a trigger signal to trigger a user circuit based on the classification signal.
    Type: Application
    Filed: March 16, 2020
    Publication date: October 22, 2020
    Inventors: Francesco Rundo, Sabrina Conoci
  • Publication number: 20200214614
    Abstract: A method includes receiving a video signal that comprises a time series of images of a face of a human, wherein the images in the time series of images comprise a set of landmark points in the face, applying tracking processing to the video signal to reveal variations over time of at least one image parameter at the set of landmark points in the human face, generating a set of variation signals indicative of variations revealed at respective landmark points in the set of landmark points, applying processing to the set of variation signals, the processing comprising artificial neural network processing to produce a reconstructed PhotoPletysmoGraphy (PPG) signal, and estimating a heart rate variability of a variable heart rate of the human as a function of the reconstructed PPG signal.
    Type: Application
    Filed: December 30, 2019
    Publication date: July 9, 2020
    Inventors: Francesco Rundo, Francesca Trenta, Sabrina Conoci, Sebastiano Battiato
  • Publication number: 20200184648
    Abstract: A method includes receiving a time series of slice images of medical imaging. The images have a region of interest located at a lung lesion. The method also includes tracking over at least one subset of slice images in a time series of slice images variations over time of at least one image parameter at the set of points in the region of interest. Classifier processing is applied to set of signals indicative of tracked time variations of the at least one image parameter at respective points in the set of points. A classification signal is indicative of the tracked time variations of the at least one image parameter reaching or failing to reach at least one classification threshold.
    Type: Application
    Filed: November 18, 2019
    Publication date: June 11, 2020
    Inventors: Francesco Rundo, Sabrina Conoci, Giuseppe Luigi Banna
  • Patent number: 10518264
    Abstract: A microreactor includes: a substrate (2; 102; 202) made of semiconductor material; a plurality of wells (5; 105; 205) separated by walls (6; 106; 206) in the substrate (2; 102; 202); a dielectric structure (7; 107; 207a, 207b) coating at least the top of the walls (6; 106; 206); a cap (3; 103; 203), bonded to the substrate (2; 102; 202) and defining a chamber (10; 110; 210) above the wells (5; 105; 205); and a biasing structure (2, 8, 13; 102, 108, 113; 202, 208a, 208b, 213), configured for setting up a voltage (VB) between the substrate (2; 102; 202) and the chamber (10; 110; 210).
    Type: Grant
    Filed: March 20, 2014
    Date of Patent: December 31, 2019
    Assignee: DISTRETTO TECNOLOGICO SICILIA MICRO E NANO SISTEMI S.C.A.R.L.
    Inventors: Sabrina Conoci, Maria Eloisa Castagna, Massimo Orazio Spata
  • Publication number: 20190383834
    Abstract: The present invention relates to a method for obtaining protein mimotopes occurring in at least two distinct 3D conformations. In a further embodiment, a method for detecting antibodies with diagnostic relevance using said mimotopes is claimed. In a preferred embodiment, said methods are applied to Alzheimer's disease.
    Type: Application
    Filed: November 27, 2017
    Publication date: December 19, 2019
    Inventors: Salvatore GUGLIELMINO, Laura Maria DE PLANO, Santina CARNAZZA, Domenico FRANCO, Alessandra NICOLETTI, Mario ZAPPIA, Sabrina CONOCI, Salvo PETRALIA
  • Publication number: 20190233896
    Abstract: The present invention relates to a method for estimating the risk factor (HR) for the onset of macular degeneration in a subject, which method comprises the evaluation of a first series of genetic parameters comprising at least the genetic loci R1210C in CFH, variants in COL8A1 and RAD51 B, and the evaluation of a second series of environmental, individual and/or clinical parameters. This method is characterized in that said risk factor (HR) is calculated by assigning a greater importance to said evaluation of the first series of genetic parameters with respect to said evaluation of the second series of environmental, individual and/or clinical parameters. The method of the present invention thus allows to estimate the genetic risk of AMD more accurately than the methods known in the art.
    Type: Application
    Filed: September 29, 2017
    Publication date: August 1, 2019
    Inventors: Massimo SPATA, Anna Rita BLANCO, Sabrina CONOCI, Maria Cristina CURATOLO
  • Publication number: 20190159735
    Abstract: Blood pressure signals are reconstructed from PhotoPlethysmoGraphy (PPG) signals by: receiving PPG signals including systolic, diastolic and dicrotic phases; and determining first and second derivatives of the PPG signals and: a first set of values indicative of lengths of the signal paths of the PPG signal, the first derivative and the second derivative thereof in the systolic, diastolic and dicrotic phases; a second set of values indicative of relative durations of the PPG signal and the first and second derivatives thereof in the systolic, diastolic and dicrotic phases; and a third set of values indicative of the time separation of peaks and/or valleys in subsequent waveforms of the PPG signal. Reconstruction also includes applying artificial neural network processing to the first, second and third set of values. The artificial neural network processing includes artificial neural network training as a function of blood pressure signals to produce reconstructed blood pressure signals.
    Type: Application
    Filed: November 19, 2018
    Publication date: May 30, 2019
    Inventors: Francesco Rundo, Sabrina Conoci
  • Publication number: 20190117096
    Abstract: A method of processing electrophysiological signals includes: receiving, over a limited time duration, sample electrocardiography (ECG) signals indicative of heart pulsatile activity occurring with a variable heart rate, wherein receiving the sample ECG signals is discontinued at an expiry of the limited time duration; receiving photoplethysmography (PPG) signals indicative of the heart pulsatile activity; determining a correlation between the sample ECG signals and the PPG signals; determining reconstructed ECG signals from the PPG signals as a function of the correlation between the sample ECG signals and the PPG signals; and estimating a heart rate variability of the variable heart rate as a function of the reconstructed ECG signals.
    Type: Application
    Filed: October 23, 2018
    Publication date: April 25, 2019
    Inventors: Francesco Rundo, Sabrina Conoci, Piero Fallica
  • Patent number: 9527726
    Abstract: A microfluidic device, comprising: a semiconductor body, having a first side and a second side, opposite to one another in a first direction; and at least one well, configured for containing a fluid, extending in the semiconductor body starting from the first side and being delimited at the bottom by a bottom surface. The microfluidic device further comprises a stirring structure integrated in the well at the bottom surface, the stirring structure including a first stirring portion coupled to the semiconductor body and provided with at least one first suspended beam configured for being moved in a second direction so as to generate, in use, agitation of the fluid present in said well.
    Type: Grant
    Filed: December 8, 2015
    Date of Patent: December 27, 2016
    Assignee: STMICROELECTRONICS S.R.L.
    Inventors: Sabrina Conoci, Paolo Ferrari
  • Patent number: 9434987
    Abstract: A cartridge for an optical analysis, including a supporting body, having a first face and a second face opposite to one another; a plurality of wells adapted to receive a biological solution to be analyzed, the wells extending in the supporting body on the first face; at least one biocompatible layer extending inside each well; an anti-reflection layer extending on the first face outside the wells; and a reflection layer extending inside each well. Methods of using same are also provided.
    Type: Grant
    Filed: November 17, 2014
    Date of Patent: September 6, 2016
    Assignee: STMicroelectronics S.r.l.
    Inventors: Sabrina Conoci, Maria Eloisa Castagna, Massimo Orazio Spata, Dario Russo
  • Publication number: 20160244807
    Abstract: A chip for biological and/or biochemical analyses includes: a supporting body, including a substrate of semiconductor material and a structural layer of biocompatible material; and a plurality of wells, designed to contain a liquid solution for the biological and/or biochemical analyses. Each well is formed by: a bottom chamber, defining a first containment volume for containing the liquid solution, and a top chamber, extending at least partially vertically aligned to, and in fluid communication with, the bottom chamber and defining a second containment volume greater than the first containment volume. The bottom chamber is formed, at least in part, in the biocompatible structural layer.
    Type: Application
    Filed: January 6, 2016
    Publication date: August 25, 2016
    Inventors: Sabrina Conoci, Maria Eloisa Castagna, Andrea Lazzara, Roberta Giuffrida
  • Patent number: 9394160
    Abstract: A microfluidic device, comprising: a semiconductor body, having a first side and a second side, opposite to one another in a first direction; and at least one well, configured for containing a fluid, extending in the semiconductor body starting from the first side and being delimited at the bottom by a bottom surface. The microfluidic device further comprises a stirring structure integrated in the well at the bottom surface, the stirring structure including a first stirring portion coupled to the semiconductor body and provided with at least one first suspended beam configured for being moved in a second direction so as to generate, in use, agitation of the fluid present in said well.
    Type: Grant
    Filed: April 10, 2014
    Date of Patent: July 19, 2016
    Assignee: STMICROELECTRONICS S.R.L.
    Inventors: Sabrina Conoci, Paolo Ferrari
  • Publication number: 20160090302
    Abstract: A microfluidic device, comprising: a semiconductor body, having a first side and a second side, opposite to one another in a first direction; and at least one well, configured for containing a fluid, extending in the semiconductor body starting from the first side and being delimited at the bottom by a bottom surface. The microfluidic device further comprises a stirring structure integrated in the well at the bottom surface, the stirring structure including a first stirring portion coupled to the semiconductor body and provided with at least one first suspended beam configured for being moved in a second direction so as to generate, in use, agitation of the fluid present in said well.
    Type: Application
    Filed: December 8, 2015
    Publication date: March 31, 2016
    Inventors: Sabrina Conoci, Paolo Ferrari
  • Publication number: 20150140563
    Abstract: A cartridge for an optical analysis, including a supporting body, having a first face and a second face opposite to one another; a plurality of wells adapted to receive a biological solution to be analyzed, the wells extending in the supporting body on the first face; at least one biocompatible layer extending inside each well; an anti-reflection layer extending on the first face outside the wells; and a reflection layer extending inside each well. Methods of using same are also provided.
    Type: Application
    Filed: November 17, 2014
    Publication date: May 21, 2015
    Inventors: Sabrina CONOCI, Maria Eloisa CASTAGNA, Massimo Orazio SPATA, Dario RUSSO
  • Publication number: 20150140562
    Abstract: An optical analyzer, configured to receiving a cartridge for biochemical analyses including a plurality of wells, and carrying out fluorescence analysis of the cartridge, in particular of the wells. The analyzer comprises a control unit (microprocessor and memory) configured to: (a) acquiring an image associated to the fluorescence emitted by the cartridge; (b) identifying, in the image, pixels belonging to boundary lines of the wells by generating a black and white binary image; (c) recognizing, between the geometrical shapes identified in step (b), the ones that best approximate a reference geometrical shape identifying an ideal well; (d) acquiring, from the starting image, values of light intensity only in portions of the image itself that in turn correspond to the regions recognized in step (c); and (e) evaluating a state of advance and/or a result of the biochemical analysis on the basis of the values of light intensity acquired in step (d).
    Type: Application
    Filed: November 17, 2014
    Publication date: May 21, 2015
    Inventors: Sabrina CONOCI, Maria Eloisa CASTAGNA, Massimo Orazio SPATA, Dario RUSSO
  • Publication number: 20140308738
    Abstract: A microfluidic device, comprising: a semiconductor body, having a first side and a second side, opposite to one another in a first direction; and at least one well, configured for containing a fluid, extending in the semiconductor body starting from the first side and being delimited at the bottom by a bottom surface. The microfluidic device further comprises a stirring structure integrated in the well at the bottom surface, the stirring structure including a first stirring portion coupled to the semiconductor body and provided with at least one first suspended beam configured for being moved in a second direction so as to generate, in use, agitation of the fluid present in said well.
    Type: Application
    Filed: April 10, 2014
    Publication date: October 16, 2014
    Applicant: STMicroelectronics S.r.l.
    Inventors: Sabrina Conoci, Paolo Ferrari
  • Publication number: 20140291152
    Abstract: A microreactor includes: a substrate (2; 102; 202) made of semiconductor material; a plurality of wells (5; 105; 205) separated by walls (6; 106; 206) in the substrate (2; 102; 202); a dielectric structure (7; 107; 207a, 207b) coating at least the top of the walls (6; 106; 206); a cap (3; 103; 203), bonded to the substrate (2; 102; 202) and defining a chamber (10; 110; 210) above the wells (5; 105; 205); and a biasing structure (2, 8, 13; 102, 108, 113; 202, 208a, 208b, 213), configured for setting up a voltage (VB) between the substrate (2; 102; 202) and the chamber (10; 110; 210).
    Type: Application
    Filed: March 20, 2014
    Publication date: October 2, 2014
    Applicant: STMicroelectronics S.r.l.
    Inventors: Sabrina CONOCI, Maria Eloisa Castagna, Massimo Orazio Spata