Patents by Inventor Sacha Nelson

Sacha Nelson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9518292
    Abstract: Provided herein are approaches for the detection, identification, and/or selective amplification of specific target species or target variants of nucleic acid sequences, even within an excess of unwanted similar sequences or variants. These approaches include methods, assays, and kits for suppression PCR that require, in part, DNA polymerase that lacks 5?-3? exonuclease activity, and a PCR primer, termed a forward selective primer or a nunchaku primer. The methods, assays, and kits provided herein are useful for a wide variety of applications, including cancer screening assays and kits, personalized screening assays, SNP (single nucleotide polymorphism) genotyping and identification, and downstream applications such as next generation high-throughput genomic sequencing and library construction.
    Type: Grant
    Filed: May 25, 2012
    Date of Patent: December 13, 2016
    Assignee: BRANDEIS UNIVERSITY
    Inventors: Ken Sugino, Serena David, Saori Kato, Sean O'Toole, Sacha Nelson
  • Publication number: 20140315211
    Abstract: Provided herein are approaches for the detection, identification, and/or selective amplification of specific target species or target variants of nucleic acid sequences, even within an excess of unwanted similar sequences or variants. These approaches include methods, assays, and kits for suppression PCR that require, in part, DNA polymerase that lacks 5?-3? exonuclease activity, and a PCR primer, termed a forward selective primer or a nunchaku primer. The methods, assays, and kits provided herein are useful for a wide variety of applications, including cancer screening assays and kits, personalized screening assays, SNP (single nucleotide polymorphism) genotyping and identification, and downstream applications such as next generation high-throughput genomic sequencing and library construction.
    Type: Application
    Filed: May 25, 2012
    Publication date: October 23, 2014
    Applicant: BRANDEIS UNIVERSITY
    Inventors: Ken Sugino, Serena David, Saori Kato, Sean O'Toole, Sacha Nelson