Abstract: Embodiments discussed herein facilitate determination of a likelihood of biochemical recurrence (BCR) of cancer (e.g., prostate cancer, etc.). One example embodiment is a method, comprising: accessing at least a portion of a digitized stained histology slide comprising a tumor; automatically segmenting, via a trained deep learning (DL) model, cribriform morphology in connection with the tumor on the at least the portion of the digitized stained histology slide; determining a cribriform-to-tumor area ratio (CAR) based at least in part on an area of the segmented cribriform morphology and an area of the tumor; and determining a risk of biochemical recurrence (BCR) of a cancer associated with the tumor based at least in part on the CAR.