Patents by Inventor Sachin Arvind BADHE

Sachin Arvind BADHE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparation of isoproterenol hydrochloride
    Patent number: 10759738
    Abstract: The present invention provides a process for preparation of isoproterenol hydrochloride (1a) comprising catalytic hydrogenation of 3?,4?-dihydroxy-2-(isopropylamino)-acetophenone hydrochloride (5a) in presence of an ion exchange resin, to provide isoproterenol hydrochloride (1a).
    Type: Grant
    Filed: January 3, 2018
    Date of Patent: September 1, 2020
    Assignee: EMCURE PHARMACEUTICALS LIMITED
    Inventors: Mukund Keshav Gurjar, Shashikant Gangaram Joshi, Jagannath Tulsiram Jagtap, Sachin Arvind Badhe
  • PROCESS FOR PREPARATION OF ISOPROTERENOL HYDROCHLORIDE
    Publication number: 20190367443
    Abstract: The present invention provides a process for preparation of isoproterenol hydrochloride (1a) comprising catalytic hydrogenation of 3?,4?-dihydroxy-2-(isopropylamino)-acetophenone hydrochloride (5a) in presence of an ion exchange resin, to provide isoproterenol hydrochloride (1a).
    Type: Application
    Filed: January 3, 2018
    Publication date: December 5, 2019
    Inventors: Mukund Keshav GURJAR, Shashikant Gangaram JOSHI, Jagannath Tulsiram JAGTAP, Sachin Arvind Badhe
  • Process for preparation of acitrecin
    Patent number: 9919993
    Abstract: The present invention provides a process for preparation of {(2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethyl)phenyl-3,7-dimethyl-nona-2,4,6,8}tetraenoate, an acitretin intermediate of formula (VI) with trans isomer ?97%, comprising of reacting 3-formyl-crotonic acid butyl ester of formula (V), substantially free of impurities, with 5-(4-methoxy-2,3,6-trimethylphenyl)-3-methyl-penta-2,4-diene-1-triphenyl phosphonium bromide of formula (IV) and isolating resultant compound of formula (VI), treating the filtrate with iodine for isomerization of the undesired cis intermediate and finally obtaining acitretin (I), with desired trans isomer ?97%.
    Type: Grant
    Filed: September 8, 2015
    Date of Patent: March 20, 2018
    Assignee: Emcure Pharmaceuticals Limited
    Inventors: Mukund Keshav Gurjar, Shashikant Gangaram Joshi, Sachin Arvind Badhe, Mangesh Gorakhanath Kamble, Samit Satish Mehta
  • PROCESS FOR PREPARATION OF ACITRECIN
    Publication number: 20170275229
    Abstract: The present invention provides a process for preparation of {(2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethyl)phenyl-3,7-dimethyl-nona-2,4,6,8}tetraenoate, an acitretin intermediate of formula (VI) with trans isomer?97%, comprising of reacting 3-formyl-crotonic acid butyl ester of formula (V), substantially free of impurities, with 5-(4-methoxy-2,3,6-trimethylphenyl)-3-methyl-penta-2,4-diene-1-triphenyl phosphonium bromide of formula (IV) and isolating resultant compound of formula (VI), treating the filtrate with iodine for isomerization of the undesired cis intermediate and finally obtaining acitretin (I), with desired trans isomer?97%.
    Type: Application
    Filed: September 8, 2015
    Publication date: September 28, 2017
    Inventors: Gurjar Mukund KESHAV, Shashikant Gangaram JOSHI, Sachin Arvind BADHE, Mangesh GORAKHANATH KAMBLE, Samit Satish MEHTA