Abstract: To ensure that a biodegradable medical implement dissolves in vivo at an appropriate dissolution rate. The biodegradable medical implement of the present invention is formed of a magnesium material, and, at least in one transverse section, a layer of magnesium crystal grains in which a (0001) plane in a hexagonal crystal structure is oriented toward a surface side is continuous over an entire circumference.

Abstract: To ensure that a biodegradable medical implement dissolves in vivo at an appropriate dissolution rate. The biodegradable medical implement of the present invention is formed of a magnesium material, and, at least in one transverse section, a layer of magnesium crystal grains in which a (0001) plane in a hexagonal crystal structure is oriented toward a surface side is continuous over an entire circumference.

Abstract: Dentition three-dimensional data and jaw-bone three-dimensional data are collected from a patient and they are combined. According to the combined data, dental crown data for making up for data on a lost tooth and occlusion data on a dental crown represented by the dental crown data are created. When an occlusion force according to the occlusion data is exerted on the occlusion face of a dental crown, a mechanical evaluation factor is produced in a jaw bone. The mechanical evaluation factor produced near the place where an artificial tooth root supporting a dental crown is to be implanted is calculated. The implantation place is determined so that the mechanical evaluation factor may be smaller and the mechanical load on the jaw bone from the opposed tooth during mastication may be lighter.

Abstract: Dentition three-dimensional data and jaw-bone three-dimensional data are collected from a patient and they are combined. According to the combined data, dental crown data for making up for data on a lost tooth and occlusion data on a dental crown represented by the dental crown data are created. When an occlusion force according to the occlusion data is exerted on the occlusion face of a dental crown, a mechanical evaluation factor is produced in a jaw bone. The mechanical evaluation factor produced near the place where an artificial tooth root supporting a dental crown is to be implanted is calculated. The implantation place is determined so that the mechanical evaluation factor may be smaller and the mechanical load on the jaw bone from the opposed tooth during mastication may be lighter.

Abstract: A dental material primer and a dentin-regenerating pulp-capping agent which exhibit an excellent dentin-regenerating action, are disclosed. The dental material primer includes a hydrolyzed ethylene-vinyl acetate copolymer in which collagen is immobilized and the dentin-regenerating pulp-capping agent includes a hydrolyzed ethylene-vinyl acetate copolymer, in which collagen is immobilized, and a binder.

Abstract: According to the present invention, an early-phase release amount of cisplatin (CCDP) is reduced and a release of cisplatin is maintained over a long period of time, such that an anticancer effect against cancer cells is enhanced while side effects are reduced. In this manner, a life prolongation effect for patients is enhanced. A microparticle preparation contains cisplatin that is intercalated into double-helical DNA. The microparticle preparation stably retains cisplatin and exhibits an excellent slow-release property. Accordingly, even when cisplatin containing severe toxicity is used, the side effects can be suppressed and an excellent anticancer effect can be provided over a long period of time.

Abstract: A dental prosthetic appliance excellent in adhesion to the oral mucosa is provided. A saponified ethylene-vinyl ester copolymer is used as a material for the dental prosthetic appliance.

Abstract: It is to provide an implant with shock-absorbing property that is able to be strongly secured in a living body as well as a manufacturing method of such implant. The implant comprising: a substrate; a first film on the substrate, which is comprised of a polymer and has a functional group that enables adsorption of calcium ions; and a second film formed on the first film and being comprised of calcium phosphate. The manufacturing method of the implant comprising: forming said first film on a substrate; and subsequently, dipping the substrate in a calcium ion solution and in a phosphate ion solution alternately as to form the second film.

Abstract: A highly reliable vehicle driver's fatigue evaluating method is provided, which is capable of quantitatively calculating a degree of fatigue of a driver seated on a seat. The degree of fatigue of the driver seated on a seat is quantitatively calculated based on an amount of rearward deflection of a lower part of a backrest portion of the seat, a load applied downward to a front part of a seating portion of the seat, and a load applied rearward to an upper part of the backrest portion, in a state of the driver being seated on the seat.

Abstract: The present invention provides a dental material primer and a dentin-regenerating pulp-capping agent which exhibit excellent a dentin-regenerating action. The present invention relates to the dental material primer comprising a hydrolyzed ethylene-vinyl acetate copolymer in which collagen is immobilized and the dentin-regenerating pulp-capping agent comprising a hydrolyzed ethylene-vinyl acetate copolymer, in which collagen is immobilized, and a binder.

Abstract: Dentition three-dimensional data and jaw-bone three-dimensional data are collected from a patient and they are combined. According to the combined data, dental crown data for making up for data on a lost tooth and occlusion data on a dental crown represented by the dental crown data are created. When an occlusion force according to the occlusion data is exerted on the occlusion face of a dental crown, a mechanical evaluation factor is produced in a jaw bone. The mechanical evaluation factor produced near the place where an artificial tooth root supporting a dental crown is to be implanted is calculated. The implantation place is determined so that the mechanical evaluation factor may be smaller and the mechanical load on the jaw bone from the opposed tooth during mastication may be lighter.

Abstract: A highly reliable vehicle driver's fatigue evaluating method is provided, which is capable of quantitatively calculating a degree of fatigue of a driver seated on a seat. The degree of fatigue of the driver seated on a seat is quantitatively calculated based on an amount of rearward deflection of a lower part of a backrest portion of the seat, a load applied downward to a front part of a seating portion of the seat, and a load applied rearward to an upper part of the backrest portion, in a state of the driver being seated on the seat.

Abstract: The present invention provides a method of and a device for measuring bulk modulus of a fine specimen using a measurement chamber, a reference chamber for comparison, and a differential pressure measurement device for detecting the pressure difference between both chambers. The specimen is contained in the measurement chamber, and in a state where both chambers are set under the standard atmospheric pressure. Then both chambers are set under the compression atmospheric pressure higher than the standard atmospheric pressure and the pressure changes are periodically given to both chambers. The initial volume of the specimen is detected from the differential pressure signals of both chambers when it is under the standard atmospheric pressure and the compression volume of the specimen is detected from the differential pressure signals of both chambers when it is under the compression atmospheric pressure. The bulk modulus of the specimen is measured by computing and analyzing these detected signals.

Abstract: Bone-adherent implant with shock-absorbing property comprising: a substrate; a first film on the substrate, which is comprised of a polymer and has a functional group that enables adsorption of calcium ions; and a second film formed on the first film and being comprised of calcium phosphate. A manufacturing method of the implant comprising: forming said first film on a substrate; and subsequently, dipping the substrate in a calcium ion solution and in a phosphate ion solution alternately as to form the second film.

Abstract: The present invention provides a tough denture and a method for producing the denture, which includes solid PMMA as a main component, being added to polar elastomer selected from a group of polyacrylate rubber copolymer, methylmethacrylate-alkylacrylate-styrene terpolymer, and fluororubber, and is fabricated in a process of being mixed and injected into a denture mold. A PMMA denture of present invention shows improved safety to living organisms and increased productivity of molding because of excellent mechanical properties and remarkable elution volume decrease after polymerization in comparison with ordinary type dentures of heat-polymerized PMMA. Furthermore, it is possible to widely apply the denture clinically because of good adaptability in oral applications with economical advantages.

Abstract: The present invention provides a tough denture and a method for the production, which comprises solid PMMA as a main component, being added polar elastomer selected from a group of polyacrylate rubber co-polymer, methylmatacrylate-alkylacrylate-styrene ter-polymer, and fluororubber, and is fabricated in a process of being mixed and injected into a denture mold.

Abstract: A living tissue replacement of crystallized glass having bioaffinity and mechanical strength is briefly obtained simply by pressure molding or machining without using a special equipment. A glass material having a softening point below its crystallization temperature and exhibiting viscous flow at temperatures below its melting point is heated at a temperature above its Tg and pressed at the temperature to mold to a desired shape, thereby manufacturing a living tissue replacement such as a dental crown. Molding can be done under a pressure of up to 20 MPa.

Abstract: A living tissue replacement of crystallized glass having bioaffinity and mechanical strength is briefly obtained simply by pressure molding or machining without using a special equipment. A glass material having a softening point below its crystallization temperature and exhibiting viscous flow at temperatures below its melting point is heated at a temperature above its Tg and pressed at the temperature to mold to a desired shape, thereby manufacturing a living tissue replacement such as a dental crown. Molding can be done under a pressure of up to 20 MPa.