Patents by Inventor Sadamitsu Aso
Sadamitsu Aso has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11972560Abstract: A machine learning device with a processor and a memory, in which the processor receives an image and calculates a feature amount of an object included in the image, the processor identifies a local part from the feature amount and calculates a local identification value, the processor calculates an overall identification value using the local identification value, and the processor generates a classifier using the local identification value and the overall identification value and stores it in the memory.Type: GrantFiled: June 24, 2019Date of Patent: April 30, 2024Assignee: HITACHI HIGH-TECH CORPORATIONInventors: Hideharu Hattori, Yasuki Kakishita, Kenko Uchida, Sadamitsu Aso, Toshinari Sakurai
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Patent number: 11676268Abstract: An image diagnosis assisting apparatus according to the present invention executes: processing of inputting an image of a tissue or cell; processing of extracting a feature amount of a tissue or cell from a processing target image; processing of extracting a feature amount of a tissue or cell from an image having a component different from that of the target image; and processing of determining presence or absence of a lesion and lesion probability for each of the target images by using a plurality of the feature amounts.Type: GrantFiled: February 26, 2018Date of Patent: June 13, 2023Assignee: HITACHI HIGH-TECH CORPORATIONInventors: Hideharu Hattori, Yasuki Kakishita, Kenko Uchida, Sadamitsu Aso, Toshinari Sakurai
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Publication number: 20220351078Abstract: An appropriate learning database and an appropriate classifier are to be created and used. A machine learning device includes: a processor configured to process a data sample; and a storage device configured to store a result of the process. The processor is configured to create a plurality of classifiers based on a plurality of learning databases. Each of the plurality of learning databases stores a plurality of learning data samples. The processor is configured to create an evaluation result on identification performance of each of the plurality of classifiers, and determine, based on the evaluation result, one learning database among the plurality of learning databases and a classifier to be generated based on the one learning database as a learning database and a classifier that are to be used.Type: ApplicationFiled: September 29, 2020Publication date: November 3, 2022Applicant: Hitachi High-Tech CorporationInventors: Hideharu HATTORI, Yasuki KAKISHITA, Kenko UCHIDA, Sadamitsu ASO, Toshinari SAKURAI
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Patent number: 11176668Abstract: Reaction values indicating based on which areas in an input image a plurality of identification results representing the states of cells or tissues are judged are calculated, and differences between a plurality of reaction values are obtained to thereby calculate the degree to which cells or tissues in an area of interest likely are in each state. Thereby, each state of cells or tissues can be visualized at an accurate position in an area of interest; therefore, diagnostic assistance to pathologist becomes possible.Type: GrantFiled: August 28, 2017Date of Patent: November 16, 2021Assignee: Hitachi High-Tech CorporationInventors: Yasuki Kakishita, Hideharu Hattori, Kenko Uchida, Sadamitsu Aso, Toshinari Sakurai
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Publication number: 20210271929Abstract: A machine learning device with a processor and a memory, in which the processor receives an image and calculates a feature amount of an object included in the image, the processor identifies a local part from the feature amount and calculates a local identification value, the processor calculates an overall identification value using the local identification value, and the processor generates a classifier using the local identification value and the overall identification value and stores it in the memory.Type: ApplicationFiled: June 24, 2019Publication date: September 2, 2021Applicant: HITACHI HIGH-TECH CORPORATIONInventors: Hideharu HATTORI, Yasuki KAKISHITA, Kenko UCHIDA, Sadamitsu ASO, Toshinari SAKURAI
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Publication number: 20210253949Abstract: The present invention improves the performance of an analyzer and facilitates the maintenance of the analyzer. This fluorescent body is produced by firing a raw material which contains: an alumina; and at least one among Fe, Cr, Bi, Tl, Ce, Tb, Eu, and Mn, wherein the raw material contains 6.1-15.9 wt % of sodium with respect to the total amount of the raw material.Type: ApplicationFiled: April 8, 2019Publication date: August 19, 2021Applicant: Hitachi High-Tech CorporationInventors: Masaaki KOMATSU, Shin IMAMURA, Takeshi ISHIDA, Isao YAMAZAKI, Sadamitsu ASO
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Patent number: 10872411Abstract: A diagnostic imaging assistance apparatus according to the present invention performs a process of inputting images of a tissue and a cell, a process of extracting feature amounts of a wide view and a narrow view from a target image to be processed, a process of classifying whether the target images having different views are normal or abnormal from the feature amounts, and a process of classifying a lesion likelihood using a classification result.Type: GrantFiled: October 26, 2017Date of Patent: December 22, 2020Assignee: HITACHI HIGH-TECH CORPORATIONInventors: Hideharu Hattori, Kenko Uchida, Sadamitsu Aso, Toshinari Sakurai, Yasuki Kakishita
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Patent number: 10858621Abstract: The present invention addresses the problem of providing: a cell dispersion measurement mechanism whereby it becomes possible to fully disperse cells regardless of the experiences of operators skilled in cell culture and it also becomes possible to determine the number or concentration of cells accurately; a cell culture apparatus equipped with the cell dispersion measurement mechanism; and a cell dispersion measurement method. The problem can be solved by circulating a cell suspension in a flow path to disperse cell masses contained in the cell suspension, and then determining over time the number or concentration of cells and/or the degree of dispersion of cells in the cell suspension that is flowing in the circulation flow path.Type: GrantFiled: July 8, 2015Date of Patent: December 8, 2020Assignee: Hitachi High-Tech CorporationInventors: Masako Kawarai, Akihiro Shimase, Sadamitsu Aso, Toshinari Sakurai, Eiichiro Takada, Kazumichi Imai
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Publication number: 20200151877Abstract: An image diagnosis assisting apparatus according to the present invention executes: processing of inputting an image of a tissue or cell; processing of extracting a feature amount of a tissue or cell from a processing target image; processing of extracting a feature amount of a tissue or cell from an image having a component different from that of the target image; and processing of determining presence or absence of a lesion and lesion probability for each of the target images by using a plurality of the feature amounts.Type: ApplicationFiled: February 26, 2018Publication date: May 14, 2020Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATIONInventors: Hideharu HATTORI, Yasuki KAKISHITA, Kenko UCHIDA, Sadamitsu ASO, Toshinari SAKURAI
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Patent number: 10453192Abstract: The present invention realizes determination of tissues and cells from an image by calculating feature values of a deformed degree of the cells even in a case where the tissues or the cells have various shapes. An image diagnosis support apparatus according to the present invention executes processing of inputting an image of cells, processing of extracting the feature values of a plurality of direction components from a target image of the processing, processing of determining whether or not the image corresponds to one-classification by using the plurality of feature values, and processing of determining whether or not the determination processing is finished with respect to all of the classifications set in advance (FIG. 1).Type: GrantFiled: January 28, 2016Date of Patent: October 22, 2019Assignee: HITACHI HIGH-TECHNOLOGIES CORPORATIONInventors: Hideharu Hattori, Yasuki Kakishita, Kenko Uchida, Sadamitsu Aso, Fumiaki Hamazato
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Publication number: 20190236779Abstract: A diagnostic imaging assistance apparatus according to the present invention performs a process of inputting images of a tissue and a cell, a process of extracting feature amounts of a wide view and a narrow view from a target image to be processed, a process of classifying whether the target images having different views are normal or abnormal from the feature amounts, and a process of classifying a lesion likelihood using a classification result.Type: ApplicationFiled: October 26, 2017Publication date: August 1, 2019Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATIONInventors: Hideharu HATTORI, Kenko UCHIDA, Sadamitsu ASO, Toshinari SAKURAI, Yasuki KAKISHITA
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Publication number: 20190172206Abstract: Reaction values indicating based on which areas in an input image a plurality of identification results representing the states of cells or tissues are judged are calculated, and differences between a plurality of reaction values are obtained to thereby calculate the degree to which cells or tissues in an area of interest likely are in each state. Thereby, each state of cells or tissues can be visualized at an accurate position in an area of interest; therefore, diagnostic assistance to pathologist becomes possible.Type: ApplicationFiled: August 28, 2017Publication date: June 6, 2019Inventors: Yasuki KAKISHITA, Hideharu HATTORI, Kenko UCHIDA, Sadamitsu ASO, Toshinari SAKURAI
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Patent number: 10266801Abstract: According to the present invention, a simple structure can be used to achieve reliable liquid delivery with no residual air, and simple attachment/detachment of a culture vessel, and thus a closed-system cell culture device exhibiting high reliability can be constructed at low cost. In the present invention, a liquid is supplied or discharged while a culture vessel is in an inclined state. The culture vessel is provided with two flow paths, namely an intake flow path and a discharge flow path, which connect a culture chamber and a connection member. Points where the flow paths join with the culture chamber are respectively configured as an intake port and a discharge port. The discharge port is provided in the position nearest to the axis of inclination of the culture vessel. The intake port is provided in a plane projected from a vertical plane including the aforementioned axis of inclination.Type: GrantFiled: December 24, 2014Date of Patent: April 23, 2019Assignee: Hitachi High-Technologies CorporationInventors: Akihiro Shimase, Kazumichi Imai, Eiichiro Takada, Sadamitsu Aso
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Patent number: 10241062Abstract: The purpose of the present invention is to eliminate the effort in placement and extraction of samples in observations using transmitted charged particles. A charged particle beam device (601) is characterized by having: a charged particle optical lens tube that irradiates a sample (6) with a primary charged particle beam; a sample stage on which a light emitting member (500) that emits light because of charged particles that have come by transmission internally in the sample (6) or scattering therefrom or a sample platform (600) having the light emitting member (500) is attachably and detachably disposed; and a detector (503) that detects the light emitted by the light emitting member.Type: GrantFiled: January 22, 2014Date of Patent: March 26, 2019Assignee: Hitachi High-Technologies CorporationInventors: Yusuke Ominami, Mitsugu Sato, Kenko Uchida, Sadamitsu Aso, Taku Sakazume, Hideo Morishita, Sukehiro Ito, Takashi Ohshima
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Patent number: 10208277Abstract: According to the present invention, a problem of closed systems, namely minimizing the number of electromagnetic valves required to control a plurality of flow paths, can be addressed, and thus a low-cost cell culture device can be achieved. In this flow-path control method for X number of flow paths satisfying X?2N, the X number of flow paths are selected by using N number of valves to simultaneously and selectively control the opening and closing of the plurality of flow paths.Type: GrantFiled: December 24, 2014Date of Patent: February 19, 2019Assignee: Hitachi High-Technologies CorporationInventors: Akihiro Shimase, Kazumichi Imai, Eiichiro Takada, Sadamitsu Aso
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Patent number: 10138456Abstract: A device which automatically performs a step in which expanded and cultured cells are diluted to a desired cell concentration and re-inoculated using a cell-concentration adjustment device having an inlet for taking in a cell suspension; an outlet for discharging a diluted cell suspension; and a flow path which is provided between the inlet and the outlet and is capable of holding a cell suspension, the flow path being provided with: a liquid delivery pump for causing a cell suspension inside to flow; a cell-concentration measurement instrument for collecting data related to a cell concentration per unit amount of the cell suspension; and a dilution-liquid container for holding a dilution liquid which is supplied to the flow path to dilute the cell suspension.Type: GrantFiled: July 8, 2015Date of Patent: November 27, 2018Assignee: HITACHI HIGH-TECHNOLOGIES CORPORATIONInventors: Akihiro Shimase, Kazumichi Imai, Sadamitsu Aso, Eiichiro Takada, Masako Kawarai, Toshinari Sakurai
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Publication number: 20180080002Abstract: The purpose of the present invention is to provide a means for dispersing cell aggregates without damaging the cells, such that a sufficient multiplication rate can be obtained in a subculture. According to the present invention, provided is a cell-suspension processing device which disperses cell aggregates included in a cell suspension. The device is provided with: an inlet for taking in the cell suspension; an outlet for discharging the processed cell suspension; and a flow path which is provided between the inlet and the outlet, and which is capable of holding the cell suspension. The flow path has, provided thereto, a liquid delivery pump for causing the cell suspension inside to flow, a cell-dispersion-degree measurement instrument for measuring the dispersion degree of cells in the cell suspension, and a narrow part for imparting shearing force to the cell suspension flowing inside.Type: ApplicationFiled: July 8, 2015Publication date: March 22, 2018Inventors: Akihiro SHIMASE, Kazumichi IMAI, Sadamitsu ASO, Eiichiro TAKADA, Masako KAWARAI, Toshinari SAKURAI
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Publication number: 20180053296Abstract: The present invention realizes determination of tissues and cells from an image by calculating feature values of a deformed degree of the cells even in a case where the tissues or the cells have various shapes. An image diagnosis support apparatus according to the present invention executes processing of inputting an image of cells, processing of extracting the feature values of a plurality of direction components from a target image of the processing, processing of determining whether or not the image corresponds to one-classification by using the plurality of feature values, and processing of determining whether or not the determination processing is finished with respect to all of the classifications set in advance (FIG. 1).Type: ApplicationFiled: January 28, 2016Publication date: February 22, 2018Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATIONInventors: Hideharu HATTORI, Yasuki KAKISHITA, Kenko UCHIDA, Sadamitsu ASO, Fumiaki HAMAZATO
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Publication number: 20170191019Abstract: The present invention addresses the problem of providing: a cell dispersion measurement mechanism whereby it becomes possible to fully disperse cells regardless of the experiences of operators skilled in cell culture and it also becomes possible to determine the number or concentration of cells accurately; a cell culture apparatus equipped with the cell dispersion measurement mechanism; and a cell dispersion measurement method. The problem can be solved by circulating a cell suspension in a flow path to disperse cell masses contained in the cell suspension, and then determining over time the number or concentration of cells and/or the degree of dispersion of cells in the cell suspension that is flowing in the circulation flow path.Type: ApplicationFiled: July 8, 2015Publication date: July 6, 2017Applicant: Hitachi High-Technologies CorporationInventors: Masako KAWARAI, Akihiro SHIMASE, Sadamitsu ASO, Toshinari SAKURAI, Eiichiro TAKADA, Kazumichi IMAI
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Publication number: 20170159003Abstract: A device which automatically performs a step in which expanded and cultured cells are diluted to a desired cell concentration and re-inoculated using a cell-concentration adjustment device having an inlet for taking in a cell suspension; an outlet for discharging a diluted cell suspension; and a flow path which is provided between the inlet and the outlet and is capable of holding a cell suspension, the flow path being provided with: a liquid delivery pump for causing a cell suspension inside to flow; a cell-concentration measurement instrument for collecting data related to a cell concentration per unit amount of the cell suspension; and a dilution-liquid container for holding a dilution liquid which is supplied to the flow path to dilute the cell suspension.Type: ApplicationFiled: July 8, 2015Publication date: June 8, 2017Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATIONInventors: Akihiro SHIMASE, Kazumichi IMAI, Sadamitsu ASO, Eiichiro TAKADA, Masako KAWARAI, Toshinari SAKURAI