Patents by Inventor Sadao Yukimoto

Sadao Yukimoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10758494
    Abstract: The present invention provides a patch containing an adhesive layer maintaining a drug, which is formed on a support, wherein the aforementioned adhesive layer comprises a thermoplastic elastomer, a non-volatile hydrocarbon oil in an amount exceeding 50 parts by weight and not more than 800 parts by weight per 100 parts by weight of the elastomer, and rivastigmine or a salt thereof, and the aforementioned adhesive layer optionally further contains a tackifier at a content in the adhesive layer of not more than 10 wt %.
    Type: Grant
    Filed: June 12, 2013
    Date of Patent: September 1, 2020
    Assignee: KM Transderm Ltd.
    Inventors: Hiroyuki Ogino, Masaoki Goto, Atsuyo Hamada, Mitsuji Akazawa, Sadao Yukimoto
  • Publication number: 20200214991
    Abstract: Provided is an adhesive sheet for adhesion to the skin, which has sufficient adhesiveness and causes low skin irritation. The adhesive sheet comprises a support and an adhesive layer formed on the support, in which the adhesive layer contains at least a thermoplastic elastomer and a non-volatile hydrocarbon oil. Further provided is a transdermal absorption preparation having sufficient adhesiveness and drug releaseability and causes low skin irritation. The transdermal absorption preparation comprises an adhesive sheet as described herein and a drug or a pharmaceutically acceptable salt thereof that is contained in the adhesive layer of the sheet.
    Type: Application
    Filed: March 16, 2020
    Publication date: July 9, 2020
    Applicant: KM Transderm Ltd.
    Inventors: Hiroyuki OGINO, Sadao YUKIMOTO, Atsuyo HAMADA, Mitsuji AKAZAWA, Masaoki GOTO
  • Patent number: 10314791
    Abstract: The invention provides an adhesive sheet for skin, which shows sufficient adhesiveness to the skin and causes low skin irritation. The adhesive sheet contains an adhesive layer formed on a support, in which the adhesive layer contains at least a thermoplastic elastomer, a non-volatile hydrocarbon oil, and polyisobutylene, but no tackifier. The polyisobutylene is a medium molecular weight polyisobutylene with a viscosity average molecular weight of more than 100,000 and not more than 500,000. The invention also provides a percutaneous absorption preparation containing a drug or a pharmaceutically acceptable salt thereof in an adhesive layer of the inventive adhesive sheet for skin.
    Type: Grant
    Filed: December 4, 2015
    Date of Patent: June 11, 2019
    Assignee: KM Transderm Ltd.
    Inventors: Hiroyuki Ogino, Sadao Yukimoto, Atsuyo Hamada, Mitsuji Akazawa, Masaoki Goto
  • Patent number: 9895320
    Abstract: A patch containing a storage layer retaining a drug or a pharmaceutically acceptable salt thereof and an adhesive layer which are formed on a support, wherein the adhesive layer contains a thermoplastic elastomer, and a non-volatile hydrocarbon oil in more than 50 parts by weight and not more than 800 parts by weight per 100 parts by weight of the elastomer, and the adhesive layer optionally further contains a tackifier at a content of not more than 10 wt %.
    Type: Grant
    Filed: September 28, 2013
    Date of Patent: February 20, 2018
    Assignee: KM Transderm Ltd.
    Inventors: Hiroyuki Ogino, Masaoki Goto, Atsuyo Hamada, Mitsuji Akazawa, Sadao Yukimoto
  • Publication number: 20170333367
    Abstract: The present invention provides an adhesive sheet for skin, which shows sufficient adhesiveness to the skin and causes low skin irritation. The first adhesive sheet for skin of the present invention has an adhesive layer formed on a support, wherein the aforementioned adhesive layer contains at least a thermoplastic elastomer, non-volatile hydrocarbon oil and polyisobutylene having a viscosity average molecular weight of more than 100,000 and not more than 500,000, and does not contain a tackifier.
    Type: Application
    Filed: December 4, 2015
    Publication date: November 23, 2017
    Applicant: KM Transderm Ltd.
    Inventors: Hiroyuki OGINO, Sadao YUKIMOTO, Atsuyo HAMADA, Mitsuji AKAZAWA, Masaoki GOTO
  • Publication number: 20160206568
    Abstract: Provided is an adhesive sheet for adhesion to the skin, which has sufficient adhesiveness and causes low skin irritation. The adhesive sheet comprises a support and an adhesive layer formed on the support, in which the adhesive layer contains at least a thermoplastic elastomer and a non-volatile hydrocarbon oil. Further provided is a transdermal absorption preparation having sufficient adhesiveness and drug releaseability and causes low skin irritation. The transdermal absorption preparation comprises an adhesive sheet as described herein and a drug or a pharmaceutically acceptable salt thereof that is contained in the adhesive layer of the sheet.
    Type: Application
    Filed: June 12, 2014
    Publication date: July 21, 2016
    Inventors: Hiroyuki OGINO, Sadao YUKIMOTO, Atsuyo HAMADA, Mitsuji AKAZAWA, Masaoki GOTO
  • Publication number: 20150374642
    Abstract: A patch containing a storage layer retaining a drug or a pharmaceutically acceptable salt thereof and an adhesive layer which are formed on a support, wherein the adhesive layer contains a thermoplastic elastomer, and a non-volatile hydrocarbon oil in more than 50 parts by weight and not more than 800 parts by weight per 100 parts by weight of the elastomer, and the adhesive layer optionally further contains a tackifier at a content of not more than 10 wt %.
    Type: Application
    Filed: September 28, 2013
    Publication date: December 31, 2015
    Inventors: Hiroyuki OGINO, Masaoki GOTO, Atsuyo HAMADA, Mitsuji AKAZAWA, Sadao YUKIMOTO
  • Publication number: 20150224063
    Abstract: The present invention provides a patch containing an adhesive layer maintaining a drug, which is formed on a support, wherein the aforementioned adhesive layer comprises a thermoplastic elastomer, a non-volatile hydrocarbon oil in an amount exceeding 50 parts by weight and not more than 800 parts by weight per 100 parts by weight of the elastomer, and rivastigmine or a salt thereof, and the aforementioned adhesive layer optionally further contains a tackifier at a content in the adhesive layer of not more than 10 wt %.
    Type: Application
    Filed: June 12, 2013
    Publication date: August 13, 2015
    Inventors: Hiroyuki Ogino, Masaoki Goto, Atsuyo Hamada, Mitsuji Akazawa, Sadao Yukimoto
  • Publication number: 20100222449
    Abstract: Disclosed is a curable composition having good storage stability which enables to obtain a cured product wherein surface tackiness after curing is almost eliminated within a short time. A cured product of such a curable composition hardly suffer from surface dirt over a long time. No crack or discoloration occurs in the surface of such a cured product even when it is used outdoors for a long time. Specifically disclosed is a curable composition containing a vinyl polymer (A) having at least one crosslinkable silyl group and a photopolymerization initiator (B).
    Type: Application
    Filed: January 18, 2007
    Publication date: September 2, 2010
    Applicant: KANEKA CORPORATION
    Inventors: Kenji Noda, Sadao Yukimoto
  • Patent number: 7115695
    Abstract: A curable composition is characterized by comprising an organic polymer having at least one silicon-containing group which has a hydroxy or hydrolyzable group bonded to the silicon atom and which is crosslinkable by forming siloxane bonds, and a specific metal salt of a carboxylic acid. The composition ensures practical curability and recovery properties and has mechanical properties including high strength and high elongation.
    Type: Grant
    Filed: July 5, 2002
    Date of Patent: October 3, 2006
    Assignee: Kaneka Corporation
    Inventors: Toshihiko Okamoto, Masashi Sakaguchi, Sadao Yukimoto, Katsuyu Wakabayashi, Junji Takase, Hiroshi Ando
  • Publication number: 20040198885
    Abstract: A curable composition is characterized by comprising an organic polymer having at least one silicon-containing group which has a hydroxy or hydrolyzable group bonded to the silicon atom and which is crosslinkable by forming siloxane bonds, and a specific metal salt of a carboxylic acid. The composition ensures practical curability and recovery properties and has mechanical properties including high strength and high elongation.
    Type: Application
    Filed: January 6, 2004
    Publication date: October 7, 2004
    Inventors: Toshihiko Okamoto, Masashi Sakaguchi, Sadao Yukimoto, Katsuyu Wakabayashi, Junji Takase, Hiroshi Ando
  • Patent number: 5290847
    Abstract: A curable composition including (A) 100 parts by weight of an organic polymer having at least one cross-linkable group containing a silicon atom to which a hydrolyzable group is bonded, and (B) 10 to 500 parts by weight of a vinyl chloride polymer. In the curable composition of the present invention, the viscosity is not lowered even after the storage for a long time and therefore the workability as sealants is not lowered.
    Type: Grant
    Filed: October 15, 1991
    Date of Patent: March 1, 1994
    Assignee: Kanegafuchi Kagaku Kogyo Kabushiki Kaisha
    Inventors: Sadao Yukimoto, Fumio Kawakubo
  • Patent number: 5063270
    Abstract: A curable composition. The composition contains(A) 100 parts of an oxyalkylene polymer having at least one silicon-containing group containing a hydroxyl group and/or hydrolyzable group bound to a silicon atom and capable of crosslinking through the formation of a siloxane bond;(B) 1 to 150 parts of a high molecular weight and/or high viscosity plasticizer; and(c) 0.1 to 20 parts of a compound having one silanol group per molecular and/or a compound capable of reacting with moisture to thereby form one silanol group per molecule. When an alkyd paint is applied onto the surface of a cured material formed from this curable composition excellent coating properties can be obtained, the other physical characteristics of the cured material being maintained.
    Type: Grant
    Filed: June 7, 1989
    Date of Patent: November 5, 1991
    Assignee: Kanegafuchi Kagaku Kogyo Kabushiki Kaisha
    Inventors: Sadao Yukimoto, Toshifumi Hirose, Hiroshi Wakabayashi, Katsuhiko Isayama
  • Patent number: 5051463
    Abstract: A curable resin composition comprising:(A) 100 parts by weight of a rubbery organic polymer having at least one silicon-containing group to the silicon atom of which a hydrolyzable group is bonded and which is cross linkable through formation of a siloxane bond in a molecule.(B) 10 to 500 parts by weight of a vinyl chloride base resin, and(C) 1 to 150 parts by weight of a polymeric plasticizer, which has improved storage stability and is easily cured in the presence of water.
    Type: Grant
    Filed: October 4, 1989
    Date of Patent: September 24, 1991
    Assignee: Kanegafuchi Chemical Industry Co., Ltd.
    Inventors: Sadao Yukimoto, Hiroshi Wakabayashi, Katsuhiko Isayama
  • Patent number: 5011900
    Abstract: A curable composition. The composition comprises (A) 100 parts by weight of an oxyalkylene polymer having at least one silicon-containing group in which a hydroxy group and/or hydrolyzable group is or are bonded to the silicon atom, said polymer being crosslinkable by formation of a siloxane bond, (B) from 0.1 to 20 parts by weight of a compound having one silanol group per molecule and/or a compound capable of forming a compound having one silanol group per molecule on reacting with moisture, and (C) from 0.1 to 20 parts by weight of a compound having an air oxidative curing unsaturated group. The composition provides a cured product which has low modulus and resistance to dust adhesion and on which an alkyd coating shows excellent coating properties.
    Type: Grant
    Filed: June 7, 1989
    Date of Patent: April 30, 1991
    Assignee: Kanegafuchi Kagaku Kogyo Kabushiki Kaisha
    Inventors: Sadao Yukimoto, Toshifumi Hirose, Hiroshi Wakabayashi, Katsuhiko Isayama
  • Patent number: 4983700
    Abstract: A curable polymer composition comprising:(A) 100 parts by weight of an oxyalkylene base polymer having at least one silicon-containing group to the silicon atom of which a hydroxy group and/or a hydrolyzable group is bonded and which is cross linkable through formation of a siloxane bond,(B) 0.1 to 20 parts by weight of at least one compound selected from the group consisting of a compound having one silanol group in the molecule and a compound which, when reacted with moisture, generates a compound having one silanol group in the molecule,(C) 0.1 to 20 parts by weight of a compound having a silicon-containing group to the silicon atom of which two hydrolyzable groups are bonded and an amino group, and(D) 0.01 to 5 parts by weight of a compound having a silicon-containing group to the silicon atom of which three hydrolyzable groups are bonded and an amino group, which composition provides a cured material having low modulus, group bond strength and improved weather resistance of bond strength.
    Type: Grant
    Filed: June 9, 1989
    Date of Patent: January 8, 1991
    Assignee: Kanegafuchi Chemical Industry, Co. Ltd.
    Inventors: Sadao Yukimoto, Toshifumi Hirose, Hiroshi Wakabayashi, Katsuhiko Isayama
  • Patent number: 4965311
    Abstract: A curing composition showing improved drying characteristics of an alkyd coating which comprises:(A) an oxyalkylene polymer having at least one silicon atom-containing group which has a hydroxyl group or a hydrolyzable group bound to a silicon atom and is capable of crosslinking by forming a siloxane bond;(B) a polymeric plasticizer and/or a viscous plasticizer; and(C) an air curing compound.
    Type: Grant
    Filed: February 2, 1989
    Date of Patent: October 23, 1990
    Assignee: Kanegafuchi Kagaku Kogyo Kabushiki Kaisha
    Inventors: Toshifumi Hirose, Sadao Yukimoto, Katsuhiko Isayama
  • Patent number: 4906707
    Abstract: A curable composition comprising an oxyalkylene polymer having reactive silicon groups and at least one other oxyalkylene polymer which contains no reactive silicon group and is either one containing hydroxyl groups and having a number average molecular weight of not less than 4,000 or one having essentially no hydroxyl group. The curable composition gives a cured product which imparts improved drying properties to alkyd paints applied to the cured product.
    Type: Grant
    Filed: December 27, 1988
    Date of Patent: March 6, 1990
    Assignee: Kanegafuchi Kagaku Kogyo Kabushiki Kaisha
    Inventors: Sadao Yukimoto, Toshifumi Hirose, Katsuhiko Isayama
  • Patent number: 4902575
    Abstract: A method of coating the cured product of an oxyalkylene polymer having reactive silicon groups with an alkyd paint. The oxyalkylene polymer is combined with a high-molecular weight plasticizer and the composition is cured and the cured product coated with an alkyd paint.
    Type: Grant
    Filed: December 22, 1988
    Date of Patent: February 20, 1990
    Assignee: Kanegafuchi Kagaku Kogyo Kabushiki Kaisha
    Inventors: Sadao Yukimoto, Toshifumi Hirose, Katsuhiko Isayama
  • Patent number: 4837401
    Abstract: A curable polymer composition comprising(A) 100 parts by weight of an organic polymer having at least one silicon-containing reactive group of the formula: ##STR1## wherein R.sup.1 is, the same or different, a C.sub.1 -C.sub.20 monovalent hydrocarbon group or a triorganosiloxy group of the formula:(R').sub.3 SiO-- (II)in which R' is, the same or different, a C.sub.1 -C.sub.20 monovalent hydrocarbon group; X is a hydroxyl group or a hydrolyzable group provided that when the number of Xs in the group (I) is at least 2, Xs are the same or different; a is 0, 1, 2 or 3; b is 0, 1 or 2; and m is an integer of 1 to 18, and(B) 0.01 to 10 parts by weight of a curing catalyst selected from the compounds of the formulas: ##STR2## wherein Q is a C.sub.1 -C.sub.20 monovalent hydrocarbon group; and Z is, the same or different, a C.sub.1 -C.sub.
    Type: Grant
    Filed: December 11, 1985
    Date of Patent: June 6, 1989
    Assignee: Kanegafuchi Chemical Industry, Co., Ltd.
    Inventors: Toshifumi Hirose, Sadao Yukimoto, Katsuhiko Isayama