Patents by Inventor Sadao Yukimoto
Sadao Yukimoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10758494Abstract: The present invention provides a patch containing an adhesive layer maintaining a drug, which is formed on a support, wherein the aforementioned adhesive layer comprises a thermoplastic elastomer, a non-volatile hydrocarbon oil in an amount exceeding 50 parts by weight and not more than 800 parts by weight per 100 parts by weight of the elastomer, and rivastigmine or a salt thereof, and the aforementioned adhesive layer optionally further contains a tackifier at a content in the adhesive layer of not more than 10 wt %.Type: GrantFiled: June 12, 2013Date of Patent: September 1, 2020Assignee: KM Transderm Ltd.Inventors: Hiroyuki Ogino, Masaoki Goto, Atsuyo Hamada, Mitsuji Akazawa, Sadao Yukimoto
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Publication number: 20200214991Abstract: Provided is an adhesive sheet for adhesion to the skin, which has sufficient adhesiveness and causes low skin irritation. The adhesive sheet comprises a support and an adhesive layer formed on the support, in which the adhesive layer contains at least a thermoplastic elastomer and a non-volatile hydrocarbon oil. Further provided is a transdermal absorption preparation having sufficient adhesiveness and drug releaseability and causes low skin irritation. The transdermal absorption preparation comprises an adhesive sheet as described herein and a drug or a pharmaceutically acceptable salt thereof that is contained in the adhesive layer of the sheet.Type: ApplicationFiled: March 16, 2020Publication date: July 9, 2020Applicant: KM Transderm Ltd.Inventors: Hiroyuki OGINO, Sadao YUKIMOTO, Atsuyo HAMADA, Mitsuji AKAZAWA, Masaoki GOTO
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Patent number: 10314791Abstract: The invention provides an adhesive sheet for skin, which shows sufficient adhesiveness to the skin and causes low skin irritation. The adhesive sheet contains an adhesive layer formed on a support, in which the adhesive layer contains at least a thermoplastic elastomer, a non-volatile hydrocarbon oil, and polyisobutylene, but no tackifier. The polyisobutylene is a medium molecular weight polyisobutylene with a viscosity average molecular weight of more than 100,000 and not more than 500,000. The invention also provides a percutaneous absorption preparation containing a drug or a pharmaceutically acceptable salt thereof in an adhesive layer of the inventive adhesive sheet for skin.Type: GrantFiled: December 4, 2015Date of Patent: June 11, 2019Assignee: KM Transderm Ltd.Inventors: Hiroyuki Ogino, Sadao Yukimoto, Atsuyo Hamada, Mitsuji Akazawa, Masaoki Goto
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Transdermal patch with different viscosity hydrocarbon oils in the drug layer and the adhesive layer
Patent number: 9895320Abstract: A patch containing a storage layer retaining a drug or a pharmaceutically acceptable salt thereof and an adhesive layer which are formed on a support, wherein the adhesive layer contains a thermoplastic elastomer, and a non-volatile hydrocarbon oil in more than 50 parts by weight and not more than 800 parts by weight per 100 parts by weight of the elastomer, and the adhesive layer optionally further contains a tackifier at a content of not more than 10 wt %.Type: GrantFiled: September 28, 2013Date of Patent: February 20, 2018Assignee: KM Transderm Ltd.Inventors: Hiroyuki Ogino, Masaoki Goto, Atsuyo Hamada, Mitsuji Akazawa, Sadao Yukimoto -
Publication number: 20170333367Abstract: The present invention provides an adhesive sheet for skin, which shows sufficient adhesiveness to the skin and causes low skin irritation. The first adhesive sheet for skin of the present invention has an adhesive layer formed on a support, wherein the aforementioned adhesive layer contains at least a thermoplastic elastomer, non-volatile hydrocarbon oil and polyisobutylene having a viscosity average molecular weight of more than 100,000 and not more than 500,000, and does not contain a tackifier.Type: ApplicationFiled: December 4, 2015Publication date: November 23, 2017Applicant: KM Transderm Ltd.Inventors: Hiroyuki OGINO, Sadao YUKIMOTO, Atsuyo HAMADA, Mitsuji AKAZAWA, Masaoki GOTO
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Publication number: 20160206568Abstract: Provided is an adhesive sheet for adhesion to the skin, which has sufficient adhesiveness and causes low skin irritation. The adhesive sheet comprises a support and an adhesive layer formed on the support, in which the adhesive layer contains at least a thermoplastic elastomer and a non-volatile hydrocarbon oil. Further provided is a transdermal absorption preparation having sufficient adhesiveness and drug releaseability and causes low skin irritation. The transdermal absorption preparation comprises an adhesive sheet as described herein and a drug or a pharmaceutically acceptable salt thereof that is contained in the adhesive layer of the sheet.Type: ApplicationFiled: June 12, 2014Publication date: July 21, 2016Inventors: Hiroyuki OGINO, Sadao YUKIMOTO, Atsuyo HAMADA, Mitsuji AKAZAWA, Masaoki GOTO
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Publication number: 20150374642Abstract: A patch containing a storage layer retaining a drug or a pharmaceutically acceptable salt thereof and an adhesive layer which are formed on a support, wherein the adhesive layer contains a thermoplastic elastomer, and a non-volatile hydrocarbon oil in more than 50 parts by weight and not more than 800 parts by weight per 100 parts by weight of the elastomer, and the adhesive layer optionally further contains a tackifier at a content of not more than 10 wt %.Type: ApplicationFiled: September 28, 2013Publication date: December 31, 2015Inventors: Hiroyuki OGINO, Masaoki GOTO, Atsuyo HAMADA, Mitsuji AKAZAWA, Sadao YUKIMOTO
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Publication number: 20150224063Abstract: The present invention provides a patch containing an adhesive layer maintaining a drug, which is formed on a support, wherein the aforementioned adhesive layer comprises a thermoplastic elastomer, a non-volatile hydrocarbon oil in an amount exceeding 50 parts by weight and not more than 800 parts by weight per 100 parts by weight of the elastomer, and rivastigmine or a salt thereof, and the aforementioned adhesive layer optionally further contains a tackifier at a content in the adhesive layer of not more than 10 wt %.Type: ApplicationFiled: June 12, 2013Publication date: August 13, 2015Inventors: Hiroyuki Ogino, Masaoki Goto, Atsuyo Hamada, Mitsuji Akazawa, Sadao Yukimoto
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Publication number: 20100222449Abstract: Disclosed is a curable composition having good storage stability which enables to obtain a cured product wherein surface tackiness after curing is almost eliminated within a short time. A cured product of such a curable composition hardly suffer from surface dirt over a long time. No crack or discoloration occurs in the surface of such a cured product even when it is used outdoors for a long time. Specifically disclosed is a curable composition containing a vinyl polymer (A) having at least one crosslinkable silyl group and a photopolymerization initiator (B).Type: ApplicationFiled: January 18, 2007Publication date: September 2, 2010Applicant: KANEKA CORPORATIONInventors: Kenji Noda, Sadao Yukimoto
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Patent number: 7115695Abstract: A curable composition is characterized by comprising an organic polymer having at least one silicon-containing group which has a hydroxy or hydrolyzable group bonded to the silicon atom and which is crosslinkable by forming siloxane bonds, and a specific metal salt of a carboxylic acid. The composition ensures practical curability and recovery properties and has mechanical properties including high strength and high elongation.Type: GrantFiled: July 5, 2002Date of Patent: October 3, 2006Assignee: Kaneka CorporationInventors: Toshihiko Okamoto, Masashi Sakaguchi, Sadao Yukimoto, Katsuyu Wakabayashi, Junji Takase, Hiroshi Ando
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Publication number: 20040198885Abstract: A curable composition is characterized by comprising an organic polymer having at least one silicon-containing group which has a hydroxy or hydrolyzable group bonded to the silicon atom and which is crosslinkable by forming siloxane bonds, and a specific metal salt of a carboxylic acid. The composition ensures practical curability and recovery properties and has mechanical properties including high strength and high elongation.Type: ApplicationFiled: January 6, 2004Publication date: October 7, 2004Inventors: Toshihiko Okamoto, Masashi Sakaguchi, Sadao Yukimoto, Katsuyu Wakabayashi, Junji Takase, Hiroshi Ando
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Patent number: 5290847Abstract: A curable composition including (A) 100 parts by weight of an organic polymer having at least one cross-linkable group containing a silicon atom to which a hydrolyzable group is bonded, and (B) 10 to 500 parts by weight of a vinyl chloride polymer. In the curable composition of the present invention, the viscosity is not lowered even after the storage for a long time and therefore the workability as sealants is not lowered.Type: GrantFiled: October 15, 1991Date of Patent: March 1, 1994Assignee: Kanegafuchi Kagaku Kogyo Kabushiki KaishaInventors: Sadao Yukimoto, Fumio Kawakubo
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Patent number: 5063270Abstract: A curable composition. The composition contains(A) 100 parts of an oxyalkylene polymer having at least one silicon-containing group containing a hydroxyl group and/or hydrolyzable group bound to a silicon atom and capable of crosslinking through the formation of a siloxane bond;(B) 1 to 150 parts of a high molecular weight and/or high viscosity plasticizer; and(c) 0.1 to 20 parts of a compound having one silanol group per molecular and/or a compound capable of reacting with moisture to thereby form one silanol group per molecule. When an alkyd paint is applied onto the surface of a cured material formed from this curable composition excellent coating properties can be obtained, the other physical characteristics of the cured material being maintained.Type: GrantFiled: June 7, 1989Date of Patent: November 5, 1991Assignee: Kanegafuchi Kagaku Kogyo Kabushiki KaishaInventors: Sadao Yukimoto, Toshifumi Hirose, Hiroshi Wakabayashi, Katsuhiko Isayama
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Patent number: 5051463Abstract: A curable resin composition comprising:(A) 100 parts by weight of a rubbery organic polymer having at least one silicon-containing group to the silicon atom of which a hydrolyzable group is bonded and which is cross linkable through formation of a siloxane bond in a molecule.(B) 10 to 500 parts by weight of a vinyl chloride base resin, and(C) 1 to 150 parts by weight of a polymeric plasticizer, which has improved storage stability and is easily cured in the presence of water.Type: GrantFiled: October 4, 1989Date of Patent: September 24, 1991Assignee: Kanegafuchi Chemical Industry Co., Ltd.Inventors: Sadao Yukimoto, Hiroshi Wakabayashi, Katsuhiko Isayama
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Patent number: 5011900Abstract: A curable composition. The composition comprises (A) 100 parts by weight of an oxyalkylene polymer having at least one silicon-containing group in which a hydroxy group and/or hydrolyzable group is or are bonded to the silicon atom, said polymer being crosslinkable by formation of a siloxane bond, (B) from 0.1 to 20 parts by weight of a compound having one silanol group per molecule and/or a compound capable of forming a compound having one silanol group per molecule on reacting with moisture, and (C) from 0.1 to 20 parts by weight of a compound having an air oxidative curing unsaturated group. The composition provides a cured product which has low modulus and resistance to dust adhesion and on which an alkyd coating shows excellent coating properties.Type: GrantFiled: June 7, 1989Date of Patent: April 30, 1991Assignee: Kanegafuchi Kagaku Kogyo Kabushiki KaishaInventors: Sadao Yukimoto, Toshifumi Hirose, Hiroshi Wakabayashi, Katsuhiko Isayama
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Patent number: 4983700Abstract: A curable polymer composition comprising:(A) 100 parts by weight of an oxyalkylene base polymer having at least one silicon-containing group to the silicon atom of which a hydroxy group and/or a hydrolyzable group is bonded and which is cross linkable through formation of a siloxane bond,(B) 0.1 to 20 parts by weight of at least one compound selected from the group consisting of a compound having one silanol group in the molecule and a compound which, when reacted with moisture, generates a compound having one silanol group in the molecule,(C) 0.1 to 20 parts by weight of a compound having a silicon-containing group to the silicon atom of which two hydrolyzable groups are bonded and an amino group, and(D) 0.01 to 5 parts by weight of a compound having a silicon-containing group to the silicon atom of which three hydrolyzable groups are bonded and an amino group, which composition provides a cured material having low modulus, group bond strength and improved weather resistance of bond strength.Type: GrantFiled: June 9, 1989Date of Patent: January 8, 1991Assignee: Kanegafuchi Chemical Industry, Co. Ltd.Inventors: Sadao Yukimoto, Toshifumi Hirose, Hiroshi Wakabayashi, Katsuhiko Isayama
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Patent number: 4965311Abstract: A curing composition showing improved drying characteristics of an alkyd coating which comprises:(A) an oxyalkylene polymer having at least one silicon atom-containing group which has a hydroxyl group or a hydrolyzable group bound to a silicon atom and is capable of crosslinking by forming a siloxane bond;(B) a polymeric plasticizer and/or a viscous plasticizer; and(C) an air curing compound.Type: GrantFiled: February 2, 1989Date of Patent: October 23, 1990Assignee: Kanegafuchi Kagaku Kogyo Kabushiki KaishaInventors: Toshifumi Hirose, Sadao Yukimoto, Katsuhiko Isayama
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Patent number: 4906707Abstract: A curable composition comprising an oxyalkylene polymer having reactive silicon groups and at least one other oxyalkylene polymer which contains no reactive silicon group and is either one containing hydroxyl groups and having a number average molecular weight of not less than 4,000 or one having essentially no hydroxyl group. The curable composition gives a cured product which imparts improved drying properties to alkyd paints applied to the cured product.Type: GrantFiled: December 27, 1988Date of Patent: March 6, 1990Assignee: Kanegafuchi Kagaku Kogyo Kabushiki KaishaInventors: Sadao Yukimoto, Toshifumi Hirose, Katsuhiko Isayama
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Patent number: 4902575Abstract: A method of coating the cured product of an oxyalkylene polymer having reactive silicon groups with an alkyd paint. The oxyalkylene polymer is combined with a high-molecular weight plasticizer and the composition is cured and the cured product coated with an alkyd paint.Type: GrantFiled: December 22, 1988Date of Patent: February 20, 1990Assignee: Kanegafuchi Kagaku Kogyo Kabushiki KaishaInventors: Sadao Yukimoto, Toshifumi Hirose, Katsuhiko Isayama
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Patent number: 4837401Abstract: A curable polymer composition comprising(A) 100 parts by weight of an organic polymer having at least one silicon-containing reactive group of the formula: ##STR1## wherein R.sup.1 is, the same or different, a C.sub.1 -C.sub.20 monovalent hydrocarbon group or a triorganosiloxy group of the formula:(R').sub.3 SiO-- (II)in which R' is, the same or different, a C.sub.1 -C.sub.20 monovalent hydrocarbon group; X is a hydroxyl group or a hydrolyzable group provided that when the number of Xs in the group (I) is at least 2, Xs are the same or different; a is 0, 1, 2 or 3; b is 0, 1 or 2; and m is an integer of 1 to 18, and(B) 0.01 to 10 parts by weight of a curing catalyst selected from the compounds of the formulas: ##STR2## wherein Q is a C.sub.1 -C.sub.20 monovalent hydrocarbon group; and Z is, the same or different, a C.sub.1 -C.sub.Type: GrantFiled: December 11, 1985Date of Patent: June 6, 1989Assignee: Kanegafuchi Chemical Industry, Co., Ltd.Inventors: Toshifumi Hirose, Sadao Yukimoto, Katsuhiko Isayama