Abstract: Crude immunoglobulin G isolated from human blood plasma is treated according to a conventional technique (such as the tricalcium phosphate adsorption method) to remove aggregates therefrom to such an extent that they are not detectable by gel filtration analysis. In order to produce an aqueous solution of immunoglobulin G having a reduced anticomplementary activity, the resulting solution is then filtered through a porous polyolefin membrane having a pore size larger than the molecular size of immunoglobulin G, in the presence of a stabilizer having surface activity. The aqueous solution of immunoglobulin G so produced is suitable for use in intravenous injection because its anticomplementary activity is low.

Abstract: There is disclosed a blood components collector unit comprising a cannula, a blood collection bag and a membrane type blood components separator which are connected in this order through tubes, and also comprising a plasma collection reservoir and a blood cell collection reservoir, both of which are connected to the blood components separator through tubes, wherein each connection through each tube is in a fixed fashion, thereby providing a unified connection, and wherein the blood collector unit is packed in a container in a sterile state. By the use of the unit of the present invention, whole blood can be collected and separated into blood components easily at a shortened period of time without any cumbersome preparatory operations. In addition, since the unit of the present invention is compact and light in weight and can be used without any other auxiliary apparatus, the unit can be conveyed to and used in any places, such as in automobiles and outdoors.