Patents by Inventor Sadhana Sharma

Sadhana Sharma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Alkylidene phosphonate esters as p-glycoprotein inducers
    Patent number: 10377781
    Abstract: The present invention relates to the alkylidene phosphonate esters of formula I wherein, R1 is selected from a group consisting of hydrogen or alkyl group; R2 is selected from a group consisting of hydrogen, hydroxy, alkyl, alkoxy, nitro, halogen, amino, N-substituted alkylamino; alkyl group is selected from a group consisting of methyl, ethyl and isopropyl; Ar is selected from a group consisting of aryl, substituted aryl, fused aryl, heteroaryl, and substituted heteroaryl. The present invention particularly relates to synthesis and p-glycoprotein induction activity of the alkylidene phosphonate esters. In addition, the invention relates to methods of using compounds for treating or preventing Alzheimer's disease.
    Type: Grant
    Filed: September 16, 2015
    Date of Patent: August 13, 2019
    Assignee: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Sandip Bharate, Ajay Kumar, Sudhakar Manda, Prashant Joshi, Sonali Bharate, Abubakar Wani, Sadhana Sharma, Ram Vishwakarma
  • Nanofibrous photoclickable hydrogel microarrays
    Patent number: 10352924
    Abstract: Nanofibrous hydrogel microarray systems that act as facile, high throughput platforms for in vitro drug discovery and investigation and screening of combinatorial effects of physical and biochemical cues on maturation and differentiation of mammalian cells.
    Type: Grant
    Filed: January 8, 2016
    Date of Patent: July 16, 2019
    Assignee: The Regents of the University of Colorado, a body corporate
    Inventors: Michael Floren, Wei Tan, Sadhana Sharma, Stephanie Bryant
  • ALKYLIDENE PHOSPHONATE ESTERS AS P-GLYCOPROTEIN INDUCERS
    Publication number: 20170275314
    Abstract: The present invention relates to the alkylidene phosphonate esters of formula I wherein, R1 is selected from a group consisting of hydrogen or alkyl group; R2 is selected from a group consisting of hydrogen, hydroxy, alkyl, alkoxy, nitro, halogen, amino, N-substituted alkylamino; alkyl group is selected from a group consisting of methyl, ethyl and isopropyl; Ar is selected from a group consisting of aryl, substituted aryl, fused aryl, heteroaryl, and substituted heteroaryl. The present invention particularly relates to synthesis and p-glycoprotein induction activity of the alkylidene phosphonate esters. In addition, the invention relates to methods of using compounds for treating or preventing Alzheimer's disease.
    Type: Application
    Filed: September 16, 2015
    Publication date: September 28, 2017
    Inventors: SANDIP BHARATE, AJAY KUMAR, SUDHAKAR MANDA, PRASHANT JOSHI, SONALI BHARATE, ABUBAKAR WANI, SADHANA SHARMA, RAM VISHWAKARMA
  • NANOFIBROUS PHOTOCLICKABLE HYDROGEL MICROARRAYS
    Publication number: 20160202241
    Abstract: Nanofibrous hydrogel microarray systems that act as facile, high throughput platforms for in vitro drug discovery and investigation and screening of combinatorial effects of physical and biochemical cues on maturation and differentiation of mammalian cells.
    Type: Application
    Filed: January 8, 2016
    Publication date: July 14, 2016
    Inventors: Michael Floren, Wei Tan, Sadhana Sharma, Stephanie Bryant
  • DIFFUSION DELIVERY SYSTEMS AND METHODS OF FABRICATION
    Publication number: 20120116307
    Abstract: The invention generally relates to diffusion delivery systems and more particularly to high precision nanoengineered devices for therapeutic applications. The device contains diffusion areas that may be fabricated between bonded substrates, and the device can possess high mechanical strength. The invention further relates to capsules containing a diffusion delivery system. The present invention also relates to methods of fabricating the diffusion delivery systems.
    Type: Application
    Filed: November 4, 2011
    Publication date: May 10, 2012
    Applicant: THE OHIO STATE UNIVERSITY
    Inventors: Mauro Ferrari, Xuewu Liu, Piyush Mohan Sinha, Bryan Smith, Sadhana Sharma
  • Diffusion Delivery Systems and Methods of Fabrication
    Publication number: 20070066138
    Abstract: The invention generally relates to diffusion delivery systems and more particularly to high precision nanoengineered devices for therapeutic applications. The device contains diffusion areas that may be fabricated between bonded substrates, and the device can possess high mechanical strength. The invention further relates to capsules containing a diffusion delivery system. The present invention also relates to methods of fabricating the diffusion delivery systems.
    Type: Application
    Filed: April 5, 2006
    Publication date: March 22, 2007
    Applicant: The Ohio State University Research Foundation
    Inventors: Mauro Ferrari, Xuewu Liu, Piyush Sinha, Bryan Smith, Sadhana Sharma