Patents by Inventor Sadiqua SHADBAR

Sadiqua SHADBAR has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Particles comprising a therapeutic or diagnostic agent and suspensions and methods of use thereof
    Patent number: 12263253
    Abstract: The invention provides particles, compositions including the particles, and methods of making the particles using electrospray. In certain embodiments, the particles allow for high concentrations of a therapeutic or diagnostic agent to be delivered at low viscosity. Particles may also exhibit beneficial properties with respect to stability.
    Type: Grant
    Filed: August 27, 2024
    Date of Patent: April 1, 2025
    Assignee: Elektrofi, Inc.
    Inventors: Chase Spenser Coffman, Lyndon Fitzgerald Charles, Jr., Paul Brown, Daniel Benjamin Dadon, Lisa Liu, Sadiqua Shadbar, Chaitanya Sudrik
  • PARTICLES AND SUSPENSIONS COMPRISING HYALURONAN DEGRADING AGENTS AND METHODS OF USE THEREOF
    Publication number: 20250082736
    Abstract: The present disclosure provides, in various embodiments, stable injectable particle suspensions of therapeutic biologics and hyaluronan degrading agents that permit administration without the need for resuspension. In particular, the compositions disclosed herein are highly concentrated, low-volume injectable particle suspensions that increase bioavailability of therapeutic biologics.
    Type: Application
    Filed: September 6, 2024
    Publication date: March 13, 2025
    Inventors: Paul Brown, Li-Chiun Cheng, Daniel Benjamin Dadon, Ashita Nair, Sakshi Singal, Chaitanya Sudrik, Winnie L. Zhang, Sadiqua Shadbar
  • Compositions and Methods for the Delivery of Therapeutic Biologics for Treatment of Disease
    Publication number: 20250026811
    Abstract: The present disclosure provides compositions and methods for treating a disease or condition in a subject in need thereof, comprising administering to the subject a pharmaceutically effective amount of a composition comprising a plurality of particles comprising at least one therapeutic biologic suspended in a pharmaceutically acceptable liquid carrier.
    Type: Application
    Filed: October 4, 2024
    Publication date: January 23, 2025
    Inventors: Paul Brown, Tyler L. Carter, Lyndon Fitzgerald Charles, JR., Chase Spenser Coffman, Daniel Benjamin Dadon, Lisa Liu, Sadiqua Shadbar, Chaitanya Sudrik, Yi Tang, Shankul Vartak
  • PARTICLES COMPRISING A THERAPEUTIC OR DIAGNOSTIC AGENT AND SUSPENSIONS AND METHODS OF USE THEREOF
    Publication number: 20240415782
    Abstract: The invention provides particles, compositions including the particles, and methods of making the particles using electrospray. In certain embodiments, the particles allow for high concentrations of a therapeutic or diagnostic agent to be delivered at low viscosity. Particles may also exhibit beneficial properties with respect to stability.
    Type: Application
    Filed: August 27, 2024
    Publication date: December 19, 2024
    Inventors: Chase Spenser Coffman, Lyndon Fitzgerald Charles, Jr., Paul Brown, Daniel Benjamin Dadon, Lisa Liu, Sadiqua Shadbar, Chaitanya Sudrik
  • Particles comprising a therapeutic or diagnostic agent and suspensions and methods of use thereof
    Patent number: 12115262
    Abstract: The invention provides particles, compositions including the particles, and methods of making the particles using electrospray. In certain embodiments, the particles allow for high concentrations of a therapeutic or diagnostic agent to be delivered at low viscosity. Particles may also exhibit beneficial properties with respect to stability.
    Type: Grant
    Filed: May 24, 2019
    Date of Patent: October 15, 2024
    Assignee: Elektrofi, Inc.
    Inventors: Chase Coffman, Lyndon Charles, Jr., Paul Brown, Daniel Benjamin Dadon, Lisa Liu, Sadiqua Shadbar, Chaitanya Sudrik
  • COMPOSITIONS AND METHODS FOR INJECTING PARTICLE SUSPENSIONS
    Publication number: 20240270864
    Abstract: The present disclosure provides high concentration injectable particle suspensions of therapeutic biologics that permit administration without the need for resuspension. In particular, the compositions disclosed herein are highly concentrated low volume injectable particle suspensions that do not require manual premixing or resuspension prior to administration.
    Type: Application
    Filed: April 12, 2024
    Publication date: August 15, 2024
    Inventors: Paul Brown, Daniel Benjamin Dadon, James W. Ivey, Moin Khwaja, Lisa Liu, Jeremy Schieferstein, Sadiqua Shadbar
  • Methods For Screening Particle Formulations Comprising Proteins
    Publication number: 20240255517
    Abstract: The present disclosure provides screening methods to predict stability of proteins in particle formulations during early stage drug development. In particular, the screening methods disclosed herein uses high throughput protocols that allow rapid identification of stable proteins in the particle formulations in a cost effective manner.
    Type: Application
    Filed: June 3, 2022
    Publication date: August 1, 2024
    Inventors: Tyler L. Carter, Lyndon Fitzgerald Charles, Jr., Chase Spenser Coffman, Daniel Benjamin Dadon, Zishu Gui, Sadiqua Shadbar, Chaitanya Sudrik, Yi Tang
  • METHODS OF FORMING PARTICLES BY CONTINUOUS DROPLET FORMATION AND DEHYDRATION
    Publication number: 20230181473
    Abstract: The present disclosure relates to methods that enable the continuous formation of droplets and dehydration of droplets to provide pharmaceutically relevant particles that can be used for therapy. In particular, the methods disclosed herein allow the controlled continuous droplet formation and dehydration that produce circular particles having low internal void spaces comprising bioactive therapeutic biologies.
    Type: Application
    Filed: April 16, 2021
    Publication date: June 15, 2023
    Inventors: Jason G. Auer, Paul Brown, Tyler L. Carter, Chase Spenser Coffman, Paul F. Herbert, James W. Ivey, Moin Khwaja, Lisa Liu, Sadiqua Shadbar, Shankul Vartak
  • COMPOSITIONS AND METHODS FOR THE DELIVERY OF THERAPEUTIC BIOLOGICS FOR TREATMENT OF DISEASE
    Publication number: 20220389084
    Abstract: The present disclosure provides compositions and methods for treating a disease or condition in a subject in need thereof, comprising administering to the subject a pharmaceutically effective amount of a composition comprising a plurality of particles comprising at least one therapeutic biologic suspended in a pharmaceutically acceptable liquid carrier.
    Type: Application
    Filed: August 8, 2022
    Publication date: December 8, 2022
    Inventors: Paul Brown, Tyler L. Carter, Lyndon Fitzgerald Charles, JR., Chase Spenser Coffman, Daniel Benjamin Dadon, Lisa Liu, Sadiqua Shadbar, Chaitanya Sudrik, Yi Tang, Shankul Vartak
  • Compositions and methods for the delivery of therapeutic biologics for treatment of disease
    Patent number: 11459376
    Abstract: The present disclosure provides compositions and methods for treating a disease or condition in a subject in need thereof, comprising administering to the subject a pharmaceutically effective amount of a composition comprising a plurality of particles comprising at least one therapeutic biologic suspended in a pharmaceutically acceptable liquid carrier.
    Type: Grant
    Filed: June 18, 2021
    Date of Patent: October 4, 2022
    Assignee: Elektrofi, Inc.
    Inventors: Paul Brown, Tyler L. Carter, Lyndon Fitzgerald Charles, Jr., Chase Spenser Coffman, Daniel Benjamin Dadon, Lisa Liu, Sadiqua Shadbar, Chaitanya Sudrik, Yi Tang, Shankul Vartak
  • COMPOSITIONS AND METHODS FOR THE DELIVERY OF THERAPEUTIC BIOLOGICS FOR TREATMENT OF DISEASE
    Publication number: 20210309724
    Abstract: The present disclosure provides compositions and methods for treating a disease or condition in a subject in need thereof, comprising administering to the subject a pharmaceutically effective amount of a composition comprising a plurality of particles comprising at least one therapeutic biologic suspended in a pharmaceutically acceptable liquid carrier.
    Type: Application
    Filed: June 18, 2021
    Publication date: October 7, 2021
    Inventors: Paul Brown, Tyler L. Carter, Lyndon Fitzgerald Charles, JR., Chase Spenser Coffman, Daniel Benjamin Dadon, Lisa Liu, Sadiqua Shadbar, Chaitanya Sudrik, Yi Tang, Shankul Vartak
  • PARTICLES COMPRISING A THERAPEUTIC OR DIAGNOSTIC AGENT AND SUSPENSIONS AND METHODS OF USE THEREOF
    Publication number: 20210220289
    Abstract: The invention provides particles, compositions including the particles, and methods of making the particles using electrospray. In certain embodiments, the particles allow for high concentrations of a therapeutic or diagnostic agent to be delivered at low viscosity. Particles may also exhibit beneficial properties with respect to stability.
    Type: Application
    Filed: May 24, 2019
    Publication date: July 22, 2021
    Inventors: Chase COFFMAN, Lyndon CHARLES, Jr., Paul BROWN, Daniel Benjamin DADON, Lisa LIU, Sadiqua SHADBAR, Chaitanya SUDRIK