Patents by Inventor Sadis Matalon

Sadis Matalon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220362334
    Abstract: Hemopexin, salubrinal, aurothioglucose, and nitrite find uses in treating pulmonary injury from several causes, alone and in combination. Methods of treatment, methods of prevention, and pharmaceutical compositions are provided with those components.
    Type: Application
    Filed: September 4, 2020
    Publication date: November 17, 2022
    Inventors: Sadis MATALON, Saurabh AGGARWALL, Tamas JILLING, Rakesh PATEL
  • Publication number: 20220305051
    Abstract: Methods for the treatment of lung injury caused by chemical inhalation, smoke inhalation or microbial infection are described. The methods include administering a therapeutically effective amount of nitrite or a nitrite formulation. Nitrite formulations that include a nitrite salt and an anti-caking agent, such as sodium bicarbonate, and the use of such formulations, is also described.
    Type: Application
    Filed: September 4, 2020
    Publication date: September 29, 2022
    Applicants: University of Pittsburgh - Of the Commonwealth System of Higher Education, The UAB Research Foundation
    Inventors: Jason Joseph Rose, Mark Thomas Gladwin, Rakesh P. Patel, Sadis Matalon
  • Publication number: 20070219224
    Abstract: Provided herein are compositions comprising a pyrimidine synthesis inhibitor and a pharmaceutically acceptable carrier Such compositions can be used in methods of increasing Na+ dependent fluid clearance by a pulmonary epithelial cell; of treating a pulmonary disease in a subject; of reducing one or more symptoms or physical signs of a respiratory syncytial virus infection in a subject; of identifying a subject at risk for respiratory syncytial virus infection and administering to the subject a composition comprising an effective amount of a pyrimidine synthesis inhibitor; of identifying a subject with a respiratory syncytial virus infection and administering to the subject a composition comprising a pyrimidine synthesis inhibitor in an amount effective to reduce Na+ dependent alveolar fluid in the subject; and of screening for a test compound that increases Na+ dependent fluid uptake by a pulmonary epithelial cell.
    Type: Application
    Filed: May 20, 2005
    Publication date: September 20, 2007
    Applicant: UAB RESEARCH FOUNDATION, THE
    Inventors: Sadis Matalon, Ian Davis