Patents by Inventor Saeko Saruwatari

Saeko Saruwatari has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11952351
    Abstract: The present embodiment provides a compound represented by the formula (1): Q-CHR2??(1) (Q is a nitrogen-containing aliphatic group containing two or more tertiary nitrogens but no oxygen, and R is an aliphatic group containing a biodegradable group). From the compound in combination with other lipids such as a lipid capable of reducing aggregation, lipid particles can be formed. Further, the compound can be used for a pharmaceutical composition to deliver an activator into cells.
    Type: Grant
    Filed: November 29, 2022
    Date of Patent: April 9, 2024
    Assignee: KABUSHIKI KAISHA TOSHIBA
    Inventors: Mitsuko Ishihara, Eiichi Akahoshi, Katsuyuki Naito, Emi Nozaki, Saeko Saruwatari
  • Publication number: 20230096664
    Abstract: According to one embodiment, a method for manufacturing a lipid particle including a drug, the method includes cooling a solution containing the lipid particle including the drug at a rate of less than or equal to 1° C. per minute.
    Type: Application
    Filed: September 9, 2022
    Publication date: March 30, 2023
    Applicant: KABUSHIKI KAISHA TOSHIBA
    Inventors: Mitsuko ISHIHARA, Saeko SARUWATARI, Arisa FUKUI
  • Publication number: 20230099139
    Abstract: The present embodiment provides a compound represented by the formula (1): Q-CHR2??(1) (Q is a nitrogen-containing aliphatic group containing two or more tertiary nitrogens but no oxygen, and R is an aliphatic group containing a biodegradable group). From the compound in combination with other lipids such as a lipid capable of reducing aggregation, lipid particles can be formed. Further, the compound can be used for a pharmaceutical composition to deliver an activator into cells.
    Type: Application
    Filed: November 29, 2022
    Publication date: March 30, 2023
    Applicant: KABUSHIKI KAISHA TOSHIBA
    Inventors: Mitsuko ISHIHARA, Eiichi AKAHOSHI, Katsuyuki NAITO, Emi NOZAKI, Saeko SARUWATARI
  • Patent number: 11548857
    Abstract: The present embodiment provides a compound represented by the formula (1): Q-CHR2??(1) (Q is a nitrogen-containing aliphatic group containing two or more tertiary nitrogens but no oxygen, and R is an aliphatic group containing a biodegradable group). From the compound in combination with other lipids such as a lipid capable of reducing aggregation, lipid particles can be formed. Further, the compound can be used for a pharmaceutical composition to deliver an activator into cells.
    Type: Grant
    Filed: March 9, 2020
    Date of Patent: January 10, 2023
    Assignee: KABUSHIKI KAISHA TOSHIBA
    Inventors: Mitsuko Ishihara, Eiichi Akahoshi, Katsuyuki Naito, Emi Nozaki, Saeko Saruwatari
  • Publication number: 20210404021
    Abstract: According to one embodiment, a method for determining a characteristic of a tumor cell group, the method includes bringing a lipid particle including a lipid membrane and a first nucleic acid included in the lipid membrane into contact with the tumor cell group (the first nucleic acid including a promoter sequence of a marker gene for determining the characteristic and a reporter gene linked to a downstream of the promoter sequence to be functionable), culturing the tumor cell group, detecting the presence or absence or an amount of a signal from a reporter protein that is expressed from the reporter gene, in each tumor cell included in the tumor cell group, and counting the number of tumor cells having the characteristic that is measured from a result of the detecting.
    Type: Application
    Filed: September 9, 2021
    Publication date: December 30, 2021
    Applicant: KABUSHIKI KAISHA TOSHIBA
    Inventors: Shigehisa KAWATA, Mitsuko ISHIHARA, Saeko SARUWATARI
  • Publication number: 20210102159
    Abstract: According to one embodiment, an examination device includes a reagent, a sheet and a detection unit. The reagent reacts with a measurement target and thereby causes light emission. The sheet is capable of adsorbing the reagent and gradually releasing the adsorbed reagent. The detection unit detects optical characteristics of the light emission caused by the reaction between the measurement target and the reagent.
    Type: Application
    Filed: December 17, 2020
    Publication date: April 8, 2021
    Applicant: KABUSHIKI KAISHA TOSHIBA
    Inventors: Saeko SARUWATARI, Yoko TOKUNO, Ikuo UEMATSU, Mitsuko ISHIHARA, Shigehisa KAWATA, Eiichi AKAHOSHI, Takaaki WADA
  • Publication number: 20200270217
    Abstract: The present embodiment provides a compound represented by the formula (1): Q-CHR2??(1) (Q is a nitrogen-containing aliphatic group containing two or more tertiary nitrogens but no oxygen, and R is an aliphatic group containing a biodegradable group). From the compound in combination with other lipids such as a lipid capable of reducing aggregation, lipid particles can be formed. Further, the compound can be used for a pharmaceutical composition to deliver an activator into cells.
    Type: Application
    Filed: March 9, 2020
    Publication date: August 27, 2020
    Applicant: KABUSHIKI KAISHA TOSHIBA
    Inventors: Mitsuko ISHIHARA, Eiichi Akahoshi, Katsuyuki Naito, Emi Nozaki, Saeko Saruwatari