Patents by Inventor Sagar D. KHARE

Sagar D. KHARE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolated phosphotriesterase polypeptides, polynucleotides encoding same and uses thereof in treating or preventing organophosphate exposure associated damage
    Patent number: 10688330
    Abstract: A genetically modified polypeptide is disclosed which comprises an amino acid sequence of phosphotriesterase (PTE) having at least twice the catalytic efficiency for a V-type nerve agent as a polypeptide which consists of the sequence as set forth in SEQ ID NO: 1, when assayed under identical conditions.
    Type: Grant
    Filed: December 10, 2015
    Date of Patent: June 23, 2020
    Assignees: Yeda Research and Development Co. Ltd., University of Washington
    Inventors: Dan S. Tawfik, Haim Leader, Yaacov Ashani, Izhack Cherny, Moshe Goldsmith, Per Jr. Greisen, Sagar D. Khare, Gustav Oberdorfer, David Baker, Sarel Fleishman, Adi Goldenzweig, Nidhi Aggarwal
  • ISOLATED PHOSPHOTRIESTERASE POLYPEPTIDES, POLYNUCLEOTIDES ENCODING SAME AND USES THEREOF IN TREATING OR PREVENTING ORGANOPHOSPHATE EXPOSURE ASSOCIATED DAMAGE
    Publication number: 20190083836
    Abstract: A genetically modified polypeptide is disclosed which comprises an amino acid sequence of phosphotriesterase (PTE) having at least twice the catalytic efficiency for a V-type nerve agent as a polypeptide which consists of the sequence as set forth in SEQ ID NO: 1, when assayed under identical conditions.
    Type: Application
    Filed: December 10, 2015
    Publication date: March 21, 2019
    Inventors: Dan S. TAWFIK, Haim LEADER, Yaacov ASHANI, Izhack CHERNY, Moshe GOLDSMITH, Per Jr. GRIESEN, Sagar D KHARE, Gustav Oberdorfer, David Baker, Sarel Fleishman, Adi Goldenzweig, Nidhi Aggarwal
  • High affinity digoxigenin binding proteins
    Patent number: 9840539
    Abstract: Isolated polypeptides with steroid binding activity and methods for their use as therapeutics and detection agents are disclosed herein.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: December 12, 2017
    Assignee: University of Washington Through its Center for Commercialization
    Inventors: David Baker, Christine E. Tinberg, Sagar D. Khare, Jiayi Dou
  • HIGH AFFINITY DIGOXIGENIN BINDING PROTEINS
    Publication number: 20150376246
    Abstract: Isolated polypeptides with steroid binding activity and methods for their use as therapeutics and detection agents are disclosed herein.
    Type: Application
    Filed: March 13, 2014
    Publication date: December 31, 2015
    Inventors: David BAKER, Christine E. TINBERG, Sagar D. KHARE, Jiayi DOU