Abstract: A device for manipulating circulation in the circulatory system of the body of a subject is disclosed. The device includes a flexible support dimensioned for covering a section of the body of the subject, a vibration inducing element embedded in or attached to the support. The support includes a patch and an attachment layer on the patch. The attachment layer includes a biocompatible adhesive suitable for attaching the patch to skin on the section of the body of the subject. The vibration inducing element is positioned in or on the support such that the vibration inducing element can transmit vibrations to the skin when the patch is adhered to the skin on the section of the body of the subject.