Patents by Inventor Sai H. Chavala

Sai H. Chavala has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibition of angiogenesis
    Patent number: 9179654
    Abstract: The present invention relates to the microRNA miR-126 and to inhibitors of miR-126 that regulate angiogenesis. The present invention provides compositions and methods for the inhibition of miR-126 and for the inhibition of angiogenesis in vivo.
    Type: Grant
    Filed: April 7, 2009
    Date of Patent: November 10, 2015
    Assignee: CORNELL RESEARCH FOUNDATION, INC.
    Inventors: Mariana Lagos-Quintana, Shahin Rafii, Sai H. Chavala
  • INHIBITION OF ANGIOGENESIS
    Publication number: 20110184043
    Abstract: The present invention relates to the microRNA miR-126 and to inhibitors of miR-126 that regulate angiogenesis. The present invention provides compositions and methods for the inhibition of miR-126 and for the inhibition of angiogenesis in vivo.
    Type: Application
    Filed: April 7, 2009
    Publication date: July 28, 2011
    Applicant: CORNELL RESEARCH FOUNDATION, INC.
    Inventors: Mariana Lagos-quintana, Shahin Rafil, Sai H. Chavala
  • GPR125 AS A MARKER FOR STEM AND PROGENITOR CELLS AND METHODS USE THEREOF
    Publication number: 20100330043
    Abstract: The present invention relates to GPR1 25 as a marker of stem and progenitor cells, including multipotent adult spermatogonial-derived stem cells (MASCs), spermatogonial stem and progenitor cells, skin stem or progenitor cells, intestinal stem or progenitor cells, neural stem or progenitor cells, and cancer stem cells. The invention provides, inter alia, methods for enriching or isolating GPR125-positive stem or progenitor cells, methods for detecting GPR125-positive stem or progenitor cells, methods for culturing GPR125-positive stem or progenitor cells, purified GPR125-positive stem or progenitor cells, therapeutic compositions containing purified GPR125-positive stem or progenitor cells, methods for targeting therapeutic agents to GPR125-positive stem and progenitor cells, and methods of treatment comprising administering GPR125-positive stem and progenitor cells, or differentiated cells derived therefrom, to subjects in need thereof.
    Type: Application
    Filed: October 23, 2007
    Publication date: December 30, 2010
    Applicants: CORNELL RESEARCH FOUNDATION, INC., SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH
    Inventors: Shahin Rafii, Sergey V. Shmelkov, Marco Seandel, Sai H. Chavala