Abstract: A container-closure system includes a container configured to hold a therapeutic liquid and having a dispensing tip configured to dispense a dose of the therapeutic liquid. A vented cap is configured to fit over at least a portion of the container including the dispensing tip and having one or more vents that allow air to pass into and out of a cavity defined between the vented cap and the dispensing tip. A second cap is configured to fit over at least a portion of the vented cap. A tamper evident seal is coupled to the second cap and one or both of the container and the vented cap.

Abstract: The present disclosure provides a model for semantic navigation for service robots to find out-of-view objects in an indoor environment. Initially, the system receives a target object to be reached by the mobile robot in the indoor environment. Further, a current location of the mobile robot is identified by a localization technique. An embedding corresponding to each of a plurality of visible regions is computed using a pretrained Graph Neural Network GNN. The GNN is pretrained using a trajectory data and a spatial relationship graph associated with the indoor environment. Further, a similarity score is computed for each of the plurality of visible regions based on the corresponding embedding using a scoring technique. An optimal visible region is identified by comparing the similarity score. Finally, a next action to be taken by the mobile robot selected from a plurality of actions based on the optimal visible region.

Abstract: Multilayer metallo-dielectric energy control coatings are disclosed in which one or more layers are formed from a hydrogenated metal nitride dielectric, which may be hydrogenated during or after dielectric deposition. Properties of the multilayer coating may be configured by appropriately tuning the hydrogen concentration (and/or the spatial profile thereof) in one or more hydrogenated metal nitride dielectric layers. One or more metal layers of the multilayer coating may be formed on a hydrogenated nitride dielectric layer, thereby facilitating adhesion of the metal with a low percolation threshold and enabling the formation of thin metal layers that exhibit substantial transparency in the visible spectrum. Optical properties of the coating may be tuned through modulation of metal-dielectric interface roughness and dispersion of metal nanoparticles in the dielectric layer.

Abstract: In state of the art methods for object goal navigation, scene understanding is implicit in their goal oriented exploration policies. Implicit scene understanding coupled with navigation is shown to be specific to tasks for which training is done and not generalizable to new tasks. Thus, embodiments of present disclosure propose a method of goal-conditioned exploration wherein scene understanding is decoupled from the exploration policies. Here, the scene understanding required for navigation is provided by a region classification network that is trained using semantic graphs representing the scene and agent can be navigated towards the goal either by using any state of the art pure exploration policies or by traversing through potential sub-goals identified based on a Co-occurrence Likelihood score calculated by using predictions from the region classification network. Hence, the method of present disclosure can be easily generalized to new tasks and new environments.

Abstract: Multilayer metallo-dielectric energy control coatings are disclosed in which one or more layers are formed from a hydrogenated metal nitride dielectric, which may be hydrogenated during or after dielectric deposition. Properties of the multilayer coating may be configured by appropriately tuning the hydrogen concentration (and/or the spatial profile thereof) in one or more hydrogenated metal nitride dielectric layers. One or more metal layers of the multilayer coating may be formed on a hydrogenated nitride dielectric layer, thereby facilitating adhesion of the metal with a low percolation threshold and enabling the formation of thin metal layers that exhibit substantial transparency in the visible spectrum. Optical properties of the coating may be tuned through modulation of metal-dielectric interface roughness and dispersion of metal nanoparticles in the dielectric layer.

Abstract: A container-closure system includes a container configured to hold a therapeutic liquid and having a dispensing tip configured to dispense a dose of the therapeutic liquid. A vented cap is configured to fit over at least a portion of the container including the dispensing tip and having one or more vents that allow air to pass into and out of a cavity defined between the vented cap and the dispensing tip. A second cap is configured to fit over at least a portion of the vented cap. A tamper evident seal is coupled to the second cap and one or both of the container and the vented cap.

Abstract: A container-closure system includes a container configured to hold a therapeutic liquid and having a dispensing tip configured to dispense a dose of the therapeutic liquid. A vented cap is configured to fit over at least a portion of the container including the dispensing tip and having one or more vents that allow air to pass into and out of a cavity defined between the vented cap and the dispensing tip. A second cap is configured to fit over at least a portion of the vented cap. A tamper evident seal is coupled to the second cap and one or both of the container and the vented cap.

Abstract: Multilayer metallo-dielectric energy control coatings are disclosed in which one or more layers are formed from a hydrogenated metal nitride dielectric, which may be hydrogenated during or after dielectric deposition. Properties of the multilayer coating may be configured by appropriately tuning the hydrogen concentration (and/or the spatial profile thereof) in one or more hydrogenated metal nitride dielectric layers. One or more metal layers of the multilayer coating may be formed on a hydrogenated nitride dielectric layer, thereby facilitating adhesion of the metal with a low percolation threshold and enabling the formation of thin metal layers that exhibit substantial transparency in the visible spectrum. Optical properties of the coating may be tuned through modulation of metal-dielectric interface roughness and dispersion of metal nanoparticles in the dielectric layer.

Abstract: A system and method are provided for non-transmission specification fair air-time, NT-AirFair, allocation control by tracking the transmission time consumed by each link to detect any increase and enforcing air-time allocation based on the pattern of usage derived therefrom.

Abstract: A protective cap for a dispenser for discharging liquids, wherein the dispenser has a liquid reservoir and an outlet opening through which the liquid is discharged into a surrounding atmosphere. The protective cap has an inner cap and an outer cap, the inner cap having a ventilation opening for communication between an interior of the protective cap and an external environment. Before use, the outer cap is mounted on the inner cap in a first position with the inner cap and the outer cap in sealing contact with each other and the ventilation opening is separated in an airtight and germproof manner from the environment, and the outer cap is movable relative to the inner cap from the first position to a second position in which the inner and outer caps are out of sealing contact with each other and the ventilation opening communicates with the environment.

Abstract: The invention relates to a protective cap for a dispenser, and to a dispenser for discharging pharmaceutical and/or cosmetical liquids, wherein the dispenser has a liquid reservoir and an outlet opening through which the liquid can be discharged into a surrounding atmosphere. The protective cap comprises an outer cap and an inner element inserted therein, wherein either at least one ventilation channel, which can be closed by means of a shut-off element and provides communication between an interior of the protective cap and an external environment, is formed between the outer cap and the inner element, or the inner element closes a ventilation opening of the outer cap.

Abstract: Ophthalmic products and related methods are described herein. These methods include a stabilizing composition comprising a therapeutically active agent which is separated from a liquid vehicle composition by a barrier. The barrier may be removed to allow the two compositions to mix to provide an ophthalmically acceptable liquid comprising the therapeutically active agent.

Abstract: Methods of treating a disease selected from dermatomyositis, prurigo nodularis, pyoderma gangrenosum, alopecia areata, hidradenitis suppurtiva, rosacea, lichen planus, giant cell arteritis, Sjogren's syndrome, gout, chronic prostatitis, posterior uveitis, vulvodynia and interstitial cystitis in a human are disclosed. Specific methods encompass the administration of (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, cyclopropyl {2-[(15)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-3-oxoisoindolin-4-yl}carboxamide or a combination thereof, or a pharmaceutically acceptable prodrug, metabolite, polymorph, salt, solvate or clathrate thereof.

Abstract: A system and method are provided for non-transmission specification fair air-time, NT-AirFair, allocation control by tracking the transmission time consumed by each link to detect any increase and enforcing air-time allocation based on the pattern of usage derived therefrom.

Abstract: A container-closure system includes a sterile vessel configured to store a preservative-free therapeutic agent. A polymeric applicator is fluidly coupled to the vessel through which the therapeutic agent is dispensed. Surfaces of the applicator that are susceptible to contamination during dispensing of the therapeutic agent comprise one or more antimicrobial additives which provide antimicrobial efficacy at the applicator surfaces.

Abstract: The invention relates to a protective cap for a dispenser, and to a dispenser for discharging pharmaceutical and/or cosmetical liquids, wherein the dispenser has a liquid reservoir and an outlet opening through which the liquid can be discharged into a surrounding atmosphere. The protective cap comprises an outer cap and an inner element inserted therein, wherein either at least one ventilation channel, which can be closed by means of a shut-off element and provides communication between an interior of the protective cap and an external environment, is formed between the outer cap and the inner element, or the inner element closes a ventilation opening of the outer cap.

Abstract: A protective cap for a dispenser for discharging liquids, wherein the dispenser has a liquid reservoir and an outlet opening through which the liquid is discharged into a surrounding atmosphere. The protective cap has an inner cap and an outer cap, the inner cap having a ventilation opening for communication between an interior of the protective cap and an external environment. Before use, the outer cap is mounted on the inner cap in a first position with the inner cap and the outer cap in sealing contact with each other and the ventilation opening is separated in an airtight and germproof manner from the environment, and the outer cap is movable relative to the inner cap from the first position to a second position in which the inner and outer caps are out of sealing contact with each other and the ventilation opening communicates with the environment.

Abstract: A system (300), apparatus (301), and method are provided for decentralized medium access control comprising an enhanced protocol for UWB MAC that includes a distributed reservation protocol (DRP) for distributed reservation of the medium (310). The invention also relates to any wireless system (300) that uses a MAC protocol comprising a distributed reservation protocol. The method comprises devices (301) announcing medium reservations in beacons (400) and devices (301) that receive such announcements respecting the reservations.