Abstract: Methods and systems for drilling a well into a subsurface formation are configured for performing a downhole measurement to generate measured logging-while-drilling (LWD) data; retrieving a machine learning model that is trained using labeled LWD data, the labeled LWD data representing one or more environmental effects each causing a respective data signature in the LWD data, each respective data signature being associated with a corresponding label identifying the environmental effect; inputting the LWD data into the machine learning model; generating, by the machine learning model based on the inputting, a classification output representing at least one environmental effect represented in the LWD data; and generating, based on the classification output, corrected LWD data that removes a change to the LWD data caused by the environmental effect. The systems and methods are configured for drilling a well into the subsurface based on the corrected LWD data.

Abstract: In the procedure for the production of a formulation of parenterally administrable pharmaceutical preparations, a liposome dispersion is used as a carrier for a pharmaceutical active compound. For the preparation of the liposome dispersion, an aqueous predispersion of one or more amphiphilic substances is fed to a high-pressure homogenizer in which the predispersion is pumped under a pressure from 600 bar to 900 bar through a homogenizer nozzle (2) having a diameter of 0.1 to 0.5 mm. The homogenizer nozzle has an inlet channel (14, 16) and an outlet channel (15, 18) and consists of a hard ceramic plate (11), in which the bore (13) is present, pressed into a steel body (12, 19). The inlet channel (14, 16) and the outlet channel (15, 18) are likewise incorporated into the steel body (12, 19).

Abstract: A method of controlling concentrations in process technology operations--preferentially in thermal separation technology--using a non-linear, pressure-compensated temperature as control signal. The method can be used flexibly within a wide operating range.